Genetic variation at the CYP2C19 gene associated with metabolic syndrome susceptibility in a South Portuguese population: results from the pilot study of the European Health Examination Survey in Portugal

Table 1 General characteristics of the participants

	Participants (n = 206)
Men	42.23% (35.49-48.98%)
Women	57.77% (51.03-64.50%)
Age (years ± SD)	56.43 ± 16.23
MetS prevalence ¹	46.12% (39.31-52.92%)
MetSscore	0.00 ± 1.41
MetS risk factors (Mean ± SD):
Waist circumference (cm)	95.50 ± 12.56
DBP (mmHg)	80.67 ± 9.96
SBP (mmHg)	131.72 ± 20.02
HDL (mg/dL)	53.51 ± 13.33
TG (mg/dL)	107.71 ± 60.29
Glucose (mg/dL)	103.29 ± 33.91
MetS related diseases
Hypertension	26.21% (20.21-32.22%)
Type 2 Diabetes	7.3% (3.73-10.83%)
Hypercholesterolemia	12.6% (8.09-17.16%)
Total	46.12% (39.31-52.92%)
Medication ²	43.20% (36.44-49.97%)
Lyfestyle risk factors
Smokers	17.96% (12.72-23.20%)
Excessive alcohol consumption	8.74% (4.88-12.59%)
Inadequate physical activity	59.71% (53.01-66.41%)
Unhealthy diet	2.92% (29.37-42.47%)

Data is presented as mean ± standard deviation for continuous variables and % (95%CI) for proportions.
¹For the metabolic syndrome definition, the newly harmonized diagnostic criteria was used [4].
²Medication for hypertension, type 2 diabetes and hypercholesterolemia was considered.
Abbreviations: CI Confidence interval, MetS metabolic syndrome, DBP diastolic blood pressure, SBP systolic blood pressure, HDL high density lipoprotein cholesterol, TG triglycerides.

ISSN: 1758-5996