Table 1 Baseline clinical characteristics of subjects with NGT and T2DM

n

62

60

Age (years)

52.03±5.59

51.81±5.77

0.837

Sex (M/F)

28/34

29/31

0.446

Waist (cm)

80.55±9.06

87.41±8.55

<0.001

Hip (cm)

91.40±5.58

93.26±6.87

0.106

WHR

0.88±0.08

0.94±0.08

<0.001

BMI (kg/m²)

24.07±3.21

25.80±2.99

0.003

Systolic BP (mmHg)

121.53±13.97

134.17±16.14

<0.001

Diastolic BP (mmHg)

78.68±9.00

84.66±10.12

0.001

TC (mM)

5.27±1.26

5.43±1.09

0.47

TG (mM)

1.25±0.66

2.27±1.77

<0.001

HDL-C (mM)

1.31±0.29

1.32±0.24

0.901

LDL -C(mM)

3.11±0.88

3.14±0.80

0.837

FFA (mM)

0.35±0.14

0.59±0.24

<0.001

FPG (mM)

5.13±0.47

7.80±2.50

<0.001

2h PG (mM)

5.84±1.10

15.61±4.34

<0.001

HbA1C (%)

5.50±0.34

7.00±1.78

<0.001

Insulin (mU)

6.42±3.62

9.68±4.17

<0.001

HOMA-β

82.63±47.49

61.25±43.16

0.011

HOMA-IR

1.48±0.90

3.20±1.33

<0.001

ALT (IU/L)

25.03±10.88

36.27±24.28

0.002

AST (IU/L)

22.73±5.34

27.23±14.41

0.026

Urea (mM)

4.67±1.21

4.76±0.98

0.674

Creatinine (μM)

62.26±14.04

58.17±13.87

0.108

Uric acid (μM)

258.81±76.83

301.57±76.99

0.003

eGFR (ml/min/1.73 m²)

104.73±21.13

117.40±31.12

0.011

Muscle mass (kg)

23.42±5.08

24.38±4.59

0.286

Fat mass (kg)

19.29±6.01

22.43±5.41

0.004

Percentage of body fat (%)

30.92±6.88

33.25±5.88

0.052

Irisin (ng/ml)

277.62±131.07

289.88 ±141.00

0.619