Table 2 Tissue and conventional Doppler Echocardiographic parameters and grade of left ventricular diastolic dysfunction by tissue Doppler echocardiograms at baseline and after 24 weeks of treatment with sitagliptin in 15 patients (SITA group) or bedtime NPH insulin in 14 patients (NPH group)
Groups/Patients | Baseline | After | 24-wk | |||||
|---|---|---|---|---|---|---|---|---|
e’ | E/e’ | E/A | LVDD | e’ | E/e’ | E/A | LVDD | |
SITA 1 | 7.0 | 10.1 | 0.9 | II | 7.0 | 2.9 | 0,5 | I |
2 | 7.0 | 5.1 | 0.6 | I | 11.0 | 4.7 | 0,6 | 0 |
3 | 8.0 | 9.5 | 0.7 | 0 | 10.0 | 5.7 | 0,6 | 0 |
4 | 7.0 | 7.6 | 0.9 | I | 9.9 | 9.8 | 1.1 | 0 |
5 | 6.0 | 9.7 | 1.8 | II | 9.1 | 8.2 | 2.0 | 0 |
6 | 7.4 | 7.2 | 1.1 | I | 7.0 | 6.3 | 0.8 | I |
7 | 8.0 | 8.1 | 1.0 | 0 | 9.0 | 10.0 | 1.0 | 0 |
8 | 8.0 | 4.3 | 0.6 | 0 | 6.8 | 5.9 | 0.6 | I |
9 | 10.0 | 6.3 | 0.8 | 0 | 8.0 | 8.4 | 1.5 | 0 |
10 | 15.0 | 6.0 | 0.8 | 0 | 7.0 | 10.4 | 0.7 | I |
11 | 7.0 | 11.1 | 0.9 | II | 8.0 | 8.8 | 1.0 | 0 |
12 | 10.0 | 5.6 | 0.7 | 0 | 8.0 | 8.1 | 0.8 | 0 |
13 | 4.7 | 12.1 | 0.8 | II | 6.1 | 6.6 | 0.5 | I |
14 | 10.0 | 6.1 | 0.9 | 0 | 6.4 | 7.5 | 0.7 | I |
15 | 7.0 | 10.0 | 1.1 | I | 5.8 | 12.8 | 0.9 | I |
NPH 1 | 7.0 | 12.0 | 0.9 | II | 7.0 | 13.3 | 1.2 | II |
2 | 6.0 | 9.8 | 0.7 | II | 5.2 | 12.0 | 0.6 | II |
3 | 7.0 | 5.7 | 0.6 | I | 7.0 | 4.7 | 0.5 | I |
4 | 6.0 | 9.8 | 0.9 | II | 10.0 | 9.2 | 1.7 | 0 |
5 | 4.0 | 16.5 | 0.9 | II | 5.0 | 12.4 | 0.7 | II |
6 | 8.0 | 5.3 | 0.7 | 0 | 9.0 | 5.3 | 0.7 | 0 |
7 | 10.0 | 7.3 | 1.0 | 0 | 10.0 | 6.0 | 0.9 | 0 |
8 | 18.0 | 2.8 | 0.7 | 0 | 8.8 | 6.6 | 0.7 | 0 |
9 | 6.1 | 12.1 | 0.9 | I | 7.5 | 10.0 | 0.8 | II |
10 | 10.0 | 6.8 | 0.9 | 0 | 6.3 | 11.4 | 0.8 | II |
11 | 4.6 | 12.0 | 0.6 | II | 6.0 | 10.8 | 0.8 | II |
12 | 7.1 | 7.7 | 0.9 | I | 7.9 | 10.0 | 1.3 | I |
13 | 5.0 | 13.6 | 0.7 | I | 4,2 | 16.2 | 0.6 | I |
14 | 8.0 | 14.2 | 1.2 | 0 | 9.0 | 10.0 | 1.0 | 0 |