Comparative efficacy of glimepiride and metformin in monotherapy of type 2 diabetes mellitus: meta-analysis of randomized controlled trials

Table 9 Adverse events

Adverse events	No. of studies	Pooled sample size	Heterogeneity			Overall effect
	No. of studies	Pooled sample size	T²	I²	P-value	OR [95% CI]	P-value
All side effects	8	1003	4.70	81%	<0.00001	0.35 [0.06, 2.01]	0.24
Hypoglycemia	5	542	0.00	0%	0.77	4.94 [2.03, 11.99]	0.0004
Gastrointestinal upset	5	763	2.27	61%	0.04	0.07 [0.01, 0.37]	0.002

ISSN: 1758-5996