Comparative efficacy of glimepiride and metformin in monotherapy of type 2 diabetes mellitus: meta-analysis of randomized controlled trials

Table 2 Results of overall efficacy

Outcome	No. of studies	Pooled sample size	Heterogeneity			Overall effect
	No. of studies		T²	I²	P-value	SMD [95% CI]	P-value
BMI	10	988	0.50	92%	<0.00001	-0.06 [-0.53, 0.40]	0.79
SBP	5	615	0.22	86%	<0.0001	0.39 [-0.06, 0.83]	0.09
DBP	5	615	0.23	87%	<0.00001	0.34 [-0.12, 0.79]	0.15
FPG	14	1611	0.03	47%	0.03	-0.02 [-0.16, 0.12]	0.80
HbA1c	13	1543	0.02	41%	0.06	0.01 [-0.13, 0.14]	0.91
PPBS	11	1099	0.18	81%	<0.00001	-0.27 [-0.56, 0.01]	0.06
TC	9	887	0.16	79%	<0.0001	0.33 [0.03, 0.63]	0.03
HDL	9	887	0.24	85%	<0.00001	0.11 [-0.25, 0.46]	0.56
LDL	6	702	0.02	29%	0.21	0.35 [0.16, 0.53]	0.0002
TG	9	887	0.05	54%	0.03	0.26 [0.05, 0.46]	0.01
FINS	10	1019	0.41	91%	<0.00001	0.07 [-0.35, 0.50]	0.73

ISSN: 1758-5996