Table 2 Characteristics of included studies in Type 2 diabetic adults

Ehrhardt [34]

USA

3 months

100

RT-CGM (DexCom SEVEN) vs. SMBG

RT-CGM occurred in four cycles (2 weeks on/1 week off) for 3 months + SMBG before meals, at bedtime and at the time of hypo- or hyperglycemia

SMBG before meals and at bedtime, at the time of hypo- or hyperglycemia

• A1C

I:50

• Change in mean and distribution of blood glucose

C:50

• Weight

• Blood Pressure

• Diabetes – related stress

Cosson [32]

France

3 months

25

RT-CGM (The GlucoDay system) vs. SMBG

48 hour of CGM at baseline and after 3 months + usual SMBG

Usual SMBG

• A1C

• Compare the 48 h CGM data at baseline with those obtained after 3 months:

I:11

C:14

- Glucose control

- Glucose variability

- Hypoglycemia

Allen [33]

USA

8 weeks

46

RT-CGM vs. SMBG

72 hour of CGM + SMBG

SMBG

• Physical activity self efficacy

I:21

C:25

• Physical activity levels

• Blood pressure

• Body mass index

• A1C

Yoo [31]

Korea

3 months

57

RT-CGM(Guardian RT) vs. SMBG

Once a month for 3 day for 12 weeks + at least three SMBG per day

SMBG at least four times a week, including fasting blood glucose and postprandial 2 h blood glucose levels for 3 months continuously

• A1C

I: 29

• Fasting blood glucose

C:28

• Post prandial 2 h blood glucose

• Lipid profiles

• Weight

• Waist circumference

• Body mass index