From: The metabolic cost of lowering blood pressure with hydrochlorothiazide
HCTZ | Valsartan | |||
---|---|---|---|---|
Variable | Baseline | End | Baseline | End |
N | 6 | 9 | ||
Male, % | 71 | 22 | ||
Age, years | 35 ± 11 | 37 ± 5 | ||
Hip circumference, cm | 110 ± 6 | 115 ± 9 | 116 ± 10 | 116 ± 10 |
Waist circumference, cm | 101 ± 12 | 104 ± 16 | 107 ± 9 | 107 ± 11 |
BMI, kg/m2 | 30.7 ± 2.4 | 31.6 ± 2.7 | 34.7 ± 3.4 | 34.9 ± 3.9 |
SBP, mmHg | 120 ± 11 | 119 ± 9 | 114 ± 8 | 108 ± 9 |
DBP, mmHg | 72 ± 8 | 71 ± 5 | 71 ± 7 | 67 ± 5 |
HR, beat/min | 74 ± 9 | 77 ± 8 | 80 ± 7 | 81 ± 7 |
Glucose, mg/dL | 95 ± 11 | 98 ± 11 | 100 ± 10 | 94 ± 11 |
Insulin, /mL | 7 ± 6 | 8 ± 4 | 7 ± 5 | 9 ± 7 |
Cholesterol, mg/dL | 209 ± 17 | 217 ± 34 | 194 ± 40 | 192 ± 30 |
Triglycerides, mg/dL | 182 ± 118 | 186 ± 52 | 153 ± 106 | 151 ± 83 |
HDL, mg/dL | 40 ± 8 | 41 ± 6 | 47 ± 14 | 49 ± 20 |
LDL, mg/dL | 142 ± 17 | 139 ± 32 | 119 ± 31 | 113 ± 27 |
HbA1c, % | 5.4 ± 0.1 | 55 ± 0.3 | 5.4 ± 0.5 | 55 ± 0.3 |
ALT, u/L | 31 ± 8 | 31 ± 12 | 27 ± 25 | 22 ± 15 |
AST, u/L | 29 ± 8 | 26 ± 6 | 21 ± 11 | 19 ± 6 |