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Table 4 Mean (SD) or median (interquartile interval) values of variables and variation after 9 months of lifestyle intervention according to SNP AdipoQ 45 T/G genotypes

From: Associations of the TNF-alpha -308 G/A, IL6 -174 G/C and AdipoQ 45 T/G polymorphisms with inflammatory and metabolic responses to lifestyle intervention in Brazilians at high cardiometabolic risk

  TT (n = 94) TG + GG (n = 37)
  Baseline 9 months p Baseline 9 months p
Energy intake (Kcal/day) 1805(720) 1558(617) .001 1811(569) 1459(407) .001
Total physical activity (min/wk) 150(60, 260) 210(60, 300) .002 190(62, 280) 210(90, 360) .008
Weight (kg) 79.4(17.1) 77.7(16.9) .004 76.9(11.9) 74.9(12.1) .003
Waist circumference (cm) 99.7(13.5) 98.9(13.1) .077 97.9(8.8) 96.5(9.1) .061
Fasting glucose (mg/dL) 99.2(11.8) 95.7(12.8) .015 98.5(10.2) 98.8(11.3) .891
Triglycerides (mg/dL) 155.5(65.9) 146.1(61.4) .087 156.9(68.1) 166.7(95.3) .432
Total cholesterol (mg/dL) 201.3(44.5) 195.3(43.6) .167 197.7(42.6) 202.8(46.3) .555
HDL-c (mg/dL) 42.2(12.4) 47.1(128.9) .009 42.5(11.8) 44.6(10.8) .242
LDL-c (mg/dL) 126.8(40.0) 118.9(38.1) .068 125.1(41.8) 126.3(41.7) .897
Apolipoprotein B (mg/dL) 96.6(22.5) 84.3(23.8) .030 91.3(23.7) 82.9(26.0) .068
Apolipoprotein A1 (mg/dL) 136.7(19.5) 140.6(20.9) .013 135.9(17.0) 142.3(17.9) .005
Insulin* (uUl/L) 10.1(6.0, 12.5) 7.0(4.3, 10.5) .001 6.8(3.9, 10.5) 5.4(3.6, 9.2) † .005
Adiponectin* (ng/dL) 11.2(7.5, 16.2) 15.0(11.1, 18.2) .005 15.7(7.9, 22.4) 18.2(12.8, 22.4) .060
Interleukin 6* (pg/dL) 2.4(1.3, 3.7) 3.4(2.2, 5.8) .009 2.7(1.2, 4.6) 3.2(2.0, 5.1) .398
C-reactive protein* (mg/dL) 0.33(0.13, 0.58) 0.29(0.07, 0.64) .040 0.42(0.21, 0.80) 0.20(0.07, 0.48) .001
TNF-α** (pg/dL) 10.8(8.9, 13.4) 9.1(7.4, 10.8) .005 10.9(10.1, 13.2) 8.3(6.9, 10.0) .004
  1. *Log-transformed for analysis.
  2. **Non-parametric test.
  3. † p = 0.054 versus TT.
  4. TNF-α: Tumor necrosis factor alpha.