Table 4 Mean (SD) or median (interquartile interval) values of variables and variation after 9 months of lifestyle intervention according to SNP AdipoQ 45 T/G genotypes
TT (n = 94) | TG + GG (n = 37) | |||||
|---|---|---|---|---|---|---|
Baseline | 9 months | p | Baseline | 9 months | p | |
Energy intake (Kcal/day) | 1805(720) | 1558(617) | .001 | 1811(569) | 1459(407) | .001 |
Total physical activity (min/wk) | 150(60, 260) | 210(60, 300) | .002 | 190(62, 280) | 210(90, 360) | .008 |
Weight (kg) | 79.4(17.1) | 77.7(16.9) | .004 | 76.9(11.9) | 74.9(12.1) | .003 |
Waist circumference (cm) | 99.7(13.5) | 98.9(13.1) | .077 | 97.9(8.8) | 96.5(9.1) | .061 |
Fasting glucose (mg/dL) | 99.2(11.8) | 95.7(12.8) | .015 | 98.5(10.2) | 98.8(11.3) | .891 |
Triglycerides (mg/dL) | 155.5(65.9) | 146.1(61.4) | .087 | 156.9(68.1) | 166.7(95.3) | .432 |
Total cholesterol (mg/dL) | 201.3(44.5) | 195.3(43.6) | .167 | 197.7(42.6) | 202.8(46.3) | .555 |
HDL-c (mg/dL) | 42.2(12.4) | 47.1(128.9) | .009 | 42.5(11.8) | 44.6(10.8) | .242 |
LDL-c (mg/dL) | 126.8(40.0) | 118.9(38.1) | .068 | 125.1(41.8) | 126.3(41.7) | .897 |
Apolipoprotein B (mg/dL) | 96.6(22.5) | 84.3(23.8) | .030 | 91.3(23.7) | 82.9(26.0) | .068 |
Apolipoprotein A1 (mg/dL) | 136.7(19.5) | 140.6(20.9) | .013 | 135.9(17.0) | 142.3(17.9) | .005 |
Insulin* (uUl/L) | 10.1(6.0, 12.5) | 7.0(4.3, 10.5) | .001 | 6.8(3.9, 10.5) | 5.4(3.6, 9.2) † | .005 |
Adiponectin* (ng/dL) | 11.2(7.5, 16.2) | 15.0(11.1, 18.2) | .005 | 15.7(7.9, 22.4) | 18.2(12.8, 22.4) | .060 |
Interleukin 6* (pg/dL) | 2.4(1.3, 3.7) | 3.4(2.2, 5.8) | .009 | 2.7(1.2, 4.6) | 3.2(2.0, 5.1) | .398 |
C-reactive protein* (mg/dL) | 0.33(0.13, 0.58) | 0.29(0.07, 0.64) | .040 | 0.42(0.21, 0.80) | 0.20(0.07, 0.48) | .001 |
TNF-α** (pg/dL) | 10.8(8.9, 13.4) | 9.1(7.4, 10.8) | .005 | 10.9(10.1, 13.2) | 8.3(6.9, 10.0) | .004 |