Table 2 Comparison of Anthropometric and DXA Measurements and Laborattory Evaluation in Patients with Familial Partial Lipodystrophy (FPLD), Familial Partial Lipodystrophy Dunnigan-type (FPLD2) and Control Group

Age (years)

40.6 ± 12.4

39.2 ± 14.5

0.73

33.3 ± 11.2

0.14

Waist (cm)

81.9 ± 9.2

82.3 ± 5.2

0.91

81.0 ± 7.2

0.89

Hip (cm)

103.1 ± 7.2

88.3 ± 5.4

<0.001

89.5 ± 5.0

<0.001

BMI (kg/m2)

25.6 ± 3.87

26.7 ± 6.6

0.76

23.5 ± 3.1

0.19

WHR

0.79 ± 0.06

0.94 ± 0.09

<0.001

0.90 ± 0.07

<0.001

Android/gynoid Fat Ratio

0.925 ± 0.1

1.177

<0.001

1.154

0.003

Total Fat (%)

43.6 ± 5.6

25.1 ± 11.0

<0.001

19.4 ± 4.9

<0.001

Troncular Fat (%)

44.2 ± 6.9

29.7 ± 11.0

<0.001

24.5 ± 6.2

<0.001

Upper Limbs Fat (%)

40.4 ± 5.2

22.9 ± 14.4

0.004

14.6 ± 5.1

<0.001

Lower Limbs Fat (%)

47.3 ± 5.6

19.4 ± 11.6

<0.001

13.7 ± 4.4

<0.001

Fat Mass (g)

28.5 ± 6.2

18.0 ± 12.0

0.002

11.7 ± 3.0

<0.001

Fat Mass Ratio (FMR)

0.93 ± 0.10

1.72 ± 0.46

<0.001

1.86 ± 0.43

<0.001

Leptin

18.1 ± 6.7

8.4 ± 9.0

<0.001

4.4 ± 2.1

<0.001

HDL Cholesterol

61.5 ± 13.4

39.4 ± 10.6

<0.001

36.5 ± 10.6

<0.001

LDL Cholesterol

126.3 ± 35.7

106.8 ± 38.9

0.20

110.7 ± 35.1

0.27

Triglycerides

109.3 ± 40.5

226.2 ± 115.3

<0.001

237.8 ± 130.6

<0.001