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Table 2 Comparison of Anthropometric and DXA Measurements and Laborattory Evaluation in Patients with Familial Partial Lipodystrophy (FPLD), Familial Partial Lipodystrophy Dunnigan-type (FPLD2) and Control Group

From: Body composition study by dual-energy x-ray absorptiometry in familial partial lipodystrophy: finding new tools for an objective evaluation

  Control (n = 16) FLPD (n = 18) p FLPD2 (n = 13) p
Age (years) 40.6 ± 12.4 39.2 ± 14.5 0.73 33.3 ± 11.2 0.14
Waist (cm) 81.9 ± 9.2 82.3 ± 5.2 0.91 81.0 ± 7.2 0.89
Hip (cm) 103.1 ± 7.2 88.3 ± 5.4 <0.001 89.5 ± 5.0 <0.001
BMI (kg/m2) 25.6 ± 3.87 26.7 ± 6.6 0.76 23.5 ± 3.1 0.19
WHR 0.79 ± 0.06 0.94 ± 0.09 <0.001 0.90 ± 0.07 <0.001
Android/gynoid Fat Ratio 0.925 ± 0.1 1.177 <0.001 1.154 0.003
Total Fat (%) 43.6 ± 5.6 25.1 ± 11.0 <0.001 19.4 ± 4.9 <0.001
Troncular Fat (%) 44.2 ± 6.9 29.7 ± 11.0 <0.001 24.5 ± 6.2 <0.001
Upper Limbs Fat (%) 40.4 ± 5.2 22.9 ± 14.4 0.004 14.6 ± 5.1 <0.001
Lower Limbs Fat (%) 47.3 ± 5.6 19.4 ± 11.6 <0.001 13.7 ± 4.4 <0.001
Fat Mass (g) 28.5 ± 6.2 18.0 ± 12.0 0.002 11.7 ± 3.0 <0.001
Fat Mass Ratio (FMR) 0.93 ± 0.10 1.72 ± 0.46 <0.001 1.86 ± 0.43 <0.001
Leptin 18.1 ± 6.7 8.4 ± 9.0 <0.001 4.4 ± 2.1 <0.001
HDL Cholesterol 61.5 ± 13.4 39.4 ± 10.6 <0.001 36.5 ± 10.6 <0.001
LDL Cholesterol 126.3 ± 35.7 106.8 ± 38.9 0.20 110.7 ± 35.1 0.27
Triglycerides 109.3 ± 40.5 226.2 ± 115.3 <0.001 237.8 ± 130.6 <0.001
  1. BMI = Body Mass Index; WHR = Waist-to-Hip Ratio.