Fatty liver in men is associated with high serum levels of small, dense low-density lipoprotein cholesterol

Table 4 Association between fatty liver and sd-LDL-C levels

	Quartiles of serum sd-LDL-C concentrations (mg/dl)
Characteristics	≤ 21.1	21.2 - 42.7	42.8 - 55.7	≥ 55.8	P value for trend
All subjects	1 (referent)	1.59 [0.85−3.20]	1.96 [1.05−3.69]	2.48 [1.32−4.70]	0.001***
Subsets of subjects
HBs-Ag (−), HCV-Ab(−)^#	1 (referent)	1.83 [0.85−4.05]	2.50 [1.18−5.43]	3.60 [1.73−7.77]	0.001***
Elevated LDL-C levels (−) ^##	1 (referent)	1.60 [0.79−3.26]	1.95 [0.92−4.16]	2.89 [1.29−6.62]	0.009***
Hypertriglyceridemia (−) ^###	1 (referent)	1.14 [0.57−2.29]	1.55 [0.76−3.23]	2.25 [1.00−5.10]	0.018***

Risk of fatty liver was estimated by logistic regression analysis using sd-LDL-C levels, age, BMI, hypertension, hyperglycemia, current alcohol consumption, and current smoking as covariables. Data are expressed as odds ratios [95% corresponding intervals]. P values for trend were obtained using the likelihood ratio test. ^#, Subjects were 385 men who were negative for both HBs-Ag and HCV-Ab. ^##, Subjects were 311 men who did not have elevated levels of LDL-C. ^###, Subjects were 336 men who did not show hypertriglyceridemia.

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