|
Characteristics
|
Quartiles of serum sd-LDL-C concentrations (mg/dl)
|
|---|
|
≤ 21.1 (n = 119)
|
21.2 - 42.7 (n = 119)
|
42.8 - 55.7 (n = 118)
|
55.8 (n = 120)
|
P value
|
|---|
|
Lipid profiles
| | | | | |
|
TG (mg/dl)
|
83.8 [72.6−95.1]
|
111.8 [100.5−123.1]
|
145.3 [134.0−156.7]
|
188.7 [177.5−200.0]
|
< 0.001
|
|
HDL-C (mg/dl)
|
63.5 [61.2−65.8]
|
57.6 [55.3−59.8]
|
52.7 [50.4−55.0]
|
49.0 [46.7−51.3]
|
< 0.001
|
|
LDL-C$ (mg/dl)
|
110.3 [105.7−115.0]
|
125.9 [121.2−130.6]
|
135.9 [131.2−140.5]
|
148.6 [144.0−153.3]
|
< 0.001
|
|
TC (mg/dl)
|
190.6 [185.6−195.7]
|
205.8 [200.8−210.9]
|
217.7 [212.6−222.8]
|
235.4 [230.4−240.4]
|
< 0.001
|
|
Apolipoprotein B (mg/dl)
|
78.0 [75.5−80.4]
|
91.9 [89.4−94.4]
|
103.5 [101.0−105.9]
|
117.6 [115.1−120]
|
< 0.001
|
|
Demographics, clinical characteristics, and laboratory data
|
|
Age (years)
|
57.9 [56.1−59.6]
|
56.8 [50.1−58.6]
|
55.3 [53.6−57.1]
|
53.8 [52.0−55.5]
|
0.007
|
|
BMI (kg/m2)
|
23.4 [22.8−23.9]
|
24.0 [23.4−24.5]
|
24.5 [24.0−25.1]
|
25.0 [24.4−25.5]
|
< 0.001
|
|
Obesity (% of subjects)
|
30.3
|
30.3
|
39.8
|
47.5
|
0.017
|
|
Glucose (mg/dl)
|
105.0 [101.8−108.2]
|
105.6 [103.0−106.2]
|
10.6.2 [103.8−108.6]
|
110.4 [105.9−115.0]
|
0.080
|
|
Hyperglycemia
| | | | | |
|
(% of subjects)
|
20.2
|
28.6
|
30.5
|
36.7
|
0.045
|
|
ALT (IU/L)
|
22.4 [19.3−25.5]
|
26.5 [23.3−29.6]
|
29.1 [26.0−32.3]
|
34.3 [31.2−37.4]
|
< 0.001
|
|
γ-GTP (IU/L)
|
31.9 [23.8−39.9]
|
40.5 [32.4−48.6]
|
47.0 [38.9−55.1]
|
62.0 [53.9−70.0]
|
< 0.001
|
|
Fatty liver (% of subjects)
|
23.5
|
34.5
|
44.0
|
57.5
|
< 0.001
|
|
Hypertension
| | | | | |
|
(% of subjects)
|
52.2
|
52.1
|
53.4
|
61.7
|
0.380
|
|
Current drinking
| | | | | |
|
(% of subjects)
|
39.5
|
39.5
|
39.8
|
32.5
|
0.587
|
|
Current smoking
| | | | | |
|
(% of subjects)
|
23.5
|
32.8
|
25.4
|
32.5
|
0.262
|
- Data are expressed as means [95% corresponding intervals] or percentages. $, LDL-C levels were calculated using the Friedwald formula.
- Continuous variables were compared by ANOVA and categorical variables were compared by Chi-square tests.
