Figure 4From: Diet high in fat and sucrose induces rapid onset of obesity-related metabolic syndrome partly through rapid response of genes involved in lipogenesis, insulin signalling and inflammation in miceEffect of the HF–HS diet on hepatic lipid accumulation. (A) Hepatic triglyceride and total cholesterol levels. (B) Photomicrographs of liver sections stained with hematoxylin-eosin and Oil Red O at week 2 (upper panel) and week 4 (lower panel). HF–HS diet: high fat–high sucrose diet. C57BL/6 J mice were fed standard chow diet or the HF–HS diet (milk fat 21% and sucrose 34%) for 2 or 4 weeks. Values are the mean ± SE, n = 6. ** P < 0.01, *** P < 0.001.Back to article page