Clinical parameters | Controls (n = 38) | Patients (n = 24) |
---|---|---|
Age (yr) |
16.97 ± 1.88 (14-20) |
17.17 ± 2.01 (14 - 20) |
Duration (yr) | ---------------------- |
7.5 ± 2.7 (4-14) |
Weight percentile |
30.43 ± 22.28 (3 - 60) |
41.42 ± 28.17 (3-77) |
Height percentile |
31.43 ± 26.59 (3-75) |
27.46 ± 26.51 (3-90) |
Biochemical markers | ||
Serum calcium (mg/dl) |
9 ± 0.22 (8.8 - 9.4) |
9.12 ± 0.19 (8.8 - 9.5) |
Serum phosphorus (mg/dl) |
3.7 ± 0.19 (3.5 - 4) |
3.75 ± 0.28 (3.1 - 4.5) |
Serum alkaline phosphatase (U/L) |
190.86 ± 44.72 (153 - 273) |
245.9 ± 137.23 (115 - 803) |
Urinary calcium (mg/g creatinine) |
181 ± 31.9 (132 - 222) |
187.75 ± 38.9 (112 - 266) |
Urinary phosphorus (mg/g creatinine) |
680.9 ± 216.1 (375 - 943) |
721.4 ± 179 (369 - 985) |
Serum P1NP (ug/dl) |
64.96 ± 34.89 (21.9 - 166.6) |
20.11 ± 6.72 (11.5 - 33.9)* |
Bone densitometry | ||
Bone mineral density (g/cm2) |
0.98 ± 0.12 (0.86-1.12) |
0.87 ± 0.10 (0.70-1.13)* |