Table 5 Comparative efficacy of therapeutic interventions for reducing A1C levels
From: Algorithm for the treatment of type 2 diabetes: a position statement of Brazilian Diabetes Society
Strategy/Drug | Expected Reduction in A1C (%) |
|---|---|
Weight reduction and increase in physical activity | 1.0 - 2.0 |
Metformin | 1.0 - 2.0 |
Insulin as additional therapy | 1.5 - 3.5 |
Sulfonylurea | 1.0 - 2.0 |
Glitazones | 0.5 - 1.4 |
GLP1 Agonists | 0.5 - 1.0 |
DPP-4 Inhibitors | 0.5 - 0.8 |
Alpha-glycosidase Inhibitors | 0.5 - 0.8 |
Glinides | 0.5 - 1.5 |