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Figure 1 | Diabetology & Metabolic Syndrome

Figure 1

From: Three-dimensional structure of β-cell-specific zinc transporter, ZnT-8, predicted from the type 2 diabetes-associated gene variant SLC30A8 R325W

Figure 1

Biological molecule image for the zinc transporter YiiP (17). The biological molecule consists of a pair of identical protein chains, each composed of (a) six transmembrane domains (blue and green) at the extracellular side, (b) a hydrophilic C-terminal domain with a αββαβ fold (red and orange) at the intracellular side, and (c) four zinc-populated sites (top-down designated as Z1 to Z4). Zinc ions are represented by gray spheres.

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