Gradient-echo magnetic resonance imaging study of pancreatic iron overload in young Egyptian beta-thalassemia major patients and effect of splenectomy

Table 5 Comparison between non splenectomized and splenectomized thalassemic patients.

Parameters	non splenectomized (8)		Splenectomized (32)		t*	P	Sig.
	Mean ± SD		Mean ± SD
Age (yrs)	12.63 ± 3.07		14.34 ± 3.30		1.34	0.19	NS
Duration of disease (yrs)	11.47 ± 3.65		13.50 ± 3.12		1.60	0.12	NS
Serum ferritin (mg/dl)	2374.63 ± 1183.90		2823.22 ± 1346.84		0.86	0.39	NS
Frequency of Blood Transfusion (wk)	3.13 ± 0.64		3.19 ± 0.69		0.23	0.82	NS
	Median	IQR	Median	IQR	Z**	P	Sig.
SIR of liver	0.679	0.451-0.967	0.707	0.273-0.857	-.135	0.89	NS
SIR of pancreas	2.95	2.047-15.562	1.743	1.014-3.211	-2.03	.042	S

*Student t test **Mann-Whitney test; SD, standard deviation; IQR, interquartile range; SIR, signal intensity ratio

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