Gradient-echo magnetic resonance imaging study of pancreatic iron overload in young Egyptian beta-thalassemia major patients and effect of splenectomy

Table 2 Comparison between thalassemic patients with normal and abnormal glucose tolerance as regards clinical and laboratory data

Parameters	Normal glucose tolerance(20)		Abnormal glucose tolerance (20)		t *	P	Sig.
	Mean ± SD		Mean ± SD
Age (yrs)	13.15 ± 3.56		14.85 ± 2.83		1.67	0.10	NS
Age at diagnosis (ms)	12.30 ± 18.63		7.20 ± 2.78		1.21	0.23	NS
Duration of chelation (yrs)	5.80 ± 3.07		5.73 ± 3.60		0.07	0.94	NS
Hb (gm/dl)	7.46 ± 1.24		7.61 ± 1.4		0.4	0.33	NS
FBG (mg/dl)	82.40 ± 7.16		138.75 ± 30.39		8.07	<0.0001	HS
PP (mg/dl)	120.80 ± 9.55		212.50 ± 47.58		8.45	<0.0001	HS
	Median	IQR	Median	IQR	Z**	P
Serum ferritin (ng/ml)	1704.5	1330-2000	3251	3050-4300	-3.03	0.002	HS

Abnormal glucose tolerance includes impaired glucose tolerance and diabetes;*Student t test **Mann-Whitney test; SD, standard deviation; IQR, interquartile range (25-75th percentile range); Hb, Hemoglobin; FBG, fasting blood glucose; PP, postprandial blood glucose

ISSN: 1758-5996