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Table 1 Clinical and laboratory data of thalassemic patients with normal glucose tolerance, impaired glucose tolerance and diabetes.

From: Gradient-echo magnetic resonance imaging study of pancreatic iron overload in young Egyptian beta-thalassemia major patients and effect of splenectomy

Parameters

Normal Glucose Tolerance(20)

Impaired Glucose Tolerance (10)

Diabetics (10)

Male/Female

14/6

5/5

6/4

 

Mean ± SD

Mean ± SD

Mean ± SD

Age (yrs)

13.15 ± 3.56

14.80 ± 3.12

14.90 ± 2.69

Age of diagnosis (ms)

8.5 ± 6.53

7.80 ± 3.22

6.70 ± 2.50

Duration of disease(yrs)

12.42 ± 3.52

13.21 ± 3.3

14.34 ± 2.66

Duration of chelation (yrs)

5.80 ± 3.07

5.55 ± 4.31

5.90 ± 2.96

Hb (g/dL)

7.46 ± 1.24

7.53 ± 1.23

7.39 ± 0.86

AST (IU/L)

64.80 ± 44.06

86.89 ± 40.07

74.80 ± 41.52

ALT (IU/L)

66.40 ± 53.74

107.50 ± 84.53

67.70 ± 27.77

Serum ferritin (ng/ml)

1999.90 ± 932.95

3223.60 ± 2188.23

3438 ± 1327.60

FBG (mg/dL)

82.40 ± 7.16

107.8 ± 16.4

145.30 ± 29.50

PP (mg/dL)

120.80 ± 9.55

175.2 ± 17.9

236.80 ± 29.81

Frequency of blood transfusion (wk interval)

3.05 ± 0.6

3.2 ± 0.63

3.4 ± 0.84

  1. SD, standard deviation; Hb, Hemoglobin; AST, aspartate aminotransferase; ALT, alanine aminotransferase; FBG, fasting blood glucose; PP, postprandial blood glucose