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  1. Review

    Tissue-specific methylation profile in obese patients with type 2 diabetes before and after Roux-en-Y gastric bypass

    Eating habits, lifestyles, and exposure to specific environmental factors can greatly impact the risk of developing type 2 diabetes (T2D), influence the genome epigenetically, and affect the expression of gene...

    Priscila Sala, Raquel Susana Matos de Miranda Torrinhas, Danielle Cristina Fonseca, Graziela Rosa Ravacci, Dan Linetzky Waitzberg and Daniel Giannella-Neto

    Diabetology & Metabolic Syndrome 2017 9:15

    Published on: 22 February 2017

  2. Research

    C-peptide is independent associated with diabetic peripheral neuropathy: a community-based study

    Because the relationship between C-peptide and diabetic peripheral neuropathy (DPN) is controversial, the aim of our study was to evaluate the relationship between C-peptide and DPN in community-based Chinese ...

    Xiaona Qiao, Hangping Zheng, Shuo Zhang, Siying Liu, Qian Xiong, Fei Mao, Zhaoyun Zhang, Jie Wen, Hongying Ye, Yiming Li and Bin Lu

    Diabetology & Metabolic Syndrome 2017 9:12

    Published on: 13 February 2017

  3. Research

    Brazilian dietary patterns and the dietary approaches to stop hypertension (DASH) diet-relationship with metabolic syndrome and newly diagnosed diabetes in the ELSA-Brasil study

    Studies evaluating dietary patterns, including the DASH diet, and their relationship with the metabolic syndrome and diabetes may help to understand the role of dairy products (low fat or full fat) in these co...

    Michele Drehmer, Andrew O. Odegaard, Maria Inês Schmidt, Bruce B. Duncan, Letícia de Oliveira Cardoso, Sheila M. Alvim Matos, Maria del Carmen B. Molina, Sandhi M. Barreto and Mark A. Pereira

    Diabetology & Metabolic Syndrome 2017 9:13

    Published on: 13 February 2017

  4. Research

    Post-challenge insulin concentration is useful for differentiating between coronary artery disease and cardiac syndrome X in subjects without known diabetes mellitus

    Cardiac syndrome X (CSX) is characterized by angina pectoris but with patent coronary arteries. Our previous study demonstrated that subjects with CSX had a higher fasting insulin-resistance (IR) than the cont...

    Kae-Woei Liang, Wayne H.-H. Sheu, Wen-Jane Lee, Wen-Lieng Lee, Hung-Chih Pan, I.-Te Lee and Jun-Sing Wang

    Diabetology & Metabolic Syndrome 2017 9:10

    Published on: 8 February 2017

  5. Research

    Health-related quality of life and utility values associated to hypoglycemia in patients with type 1 diabetes mellitus treated in the Brazilian Public Health System: a multicenter study

    Hypoglycemia is a critical and limiting factor of a good metabolic control and can adversely affect the quality of life of diabetic patients. The aim of the study was to evaluate the health-related quality of ...

    Luciana Bahia, Rosane Kupfer, Denise Momesso, Debora A. P. Cabral, Balduino Tschiedel, Marcia Puñales, Suzana Lavigne, Cristina F. S. Façanha, Adriana C. Forti, Angela D. N. Mendes and Bernardo R. Tura

    Diabetology & Metabolic Syndrome 2017 9:9

    Published on: 28 January 2017

  6. Research

    Prevalence and risk factors of diabetes in a large community-based study in North India: results from a STEPS survey in Punjab, India

    India is the diabetes capital with home to 69.1 million people with DM, the second highest number of cases after China. Recent epidemiological evidence indicates a rising DM epidemic across all classes, both a...

    Jaya Prasad Tripathy, J. S. Thakur, Gursimer Jeet, Sohan Chawla, Sanjay Jain, Arnab Pal, Rajendra Prasad and Rajiv Saran

    Diabetology & Metabolic Syndrome 2017 9:8

    Published on: 23 January 2017

  7. Research

    Interaction between peroxisome proliferator-activated receptor gamma polymorphism and obesity on type 2 diabetes in a Chinese Han population

    The aim of this study was to investigate the association of four single nucleotide polymorphisms (SNPs) of peroxisome proliferator-activated receptor gamma (PPARG) with type 2 diabetes mellitus (T2DM) risk and...

    Xiaohui Lv, Li Zhang, Jiayu Sun, Zhigang Cai, Qing Gu, Ruipeng Zhang and Aiyun Shan

    Diabetology & Metabolic Syndrome 2017 9:7

    Published on: 19 January 2017

  8. Short report

    Clinical aspects of pancreatogenic diabetes secondary to hereditary pancreatitis

    Hereditary pancreatitis is a rare inherited form of pancreatitis, characterized by recurrent episodes of acute pancreatitis with early onset and/or chronic pancreatitis, and presenting brittle diabetes, compos...

    Marcio Garrison Dytz, Pedro Arthur Hamamoto Marcelino, Olga de Castro Santos, Lenita Zajdenverg, Flavia Lucia Conceição, Tânia Maria Ortiga-Carvalho and Melanie Rodacki

    Diabetology & Metabolic Syndrome 2017 9:4

    Published on: 13 January 2017

  9. Research

    Improvement of quality of life through glycemic control by liraglutide, a GLP-1 analog, in insulin-naive patients with type 2 diabetes mellitus: the PAGE1 study

    In addition to achieving good glycemic control, diabetes care management aims to improve the quality of life (QOL) in patients. Treatment-associated difficulties and side effects frequently cause deterioration...

    Hitoshi Ishii, Tetsuji Niiya, Yasuhiro Ono, Naoyuki Inaba, Hideaki Jinnouchi and Hirotaka Watada

    Diabetology & Metabolic Syndrome 2017 9:3

    Published on: 7 January 2017

  10. Research

    Diagnostic protocol for gestational diabetes mellitus (GDM) (IADPSG/ADA, 2011): influence on the occurrence of GDM and mild gestational hyperglycemia (MGH) and on the perinatal outcomes

    In August 2011, the Specialized Center for Diabetes and Pregnancy of the Botucatu Medical School/Unesp adopted a new diagnostic protocol for gestational diabetes mellitus, recommended by the American Diabetes ...

    Mariana Pinto Sirimarco, Helena Maciel Guerra, Eduardo Guimarães Lisboa, Joice Monalisa Vernini, Bianca Nicolosi Cassetari, Roberto Antonio de Araujo Costa, Marilza Vieira Cunha Rudge and Iracema de Mattos Paranhos Calderon

    Diabetology & Metabolic Syndrome 2017 9:2

    Published on: 3 January 2017

  11. Research

    Serotonin improves glucose metabolism by Serotonylation of the small GTPase Rab4 in L6 skeletal muscle cells

    Serotonin (5-HT) improves insulin sensitivity and glucose metabolism, however, the underlying molecular mechanism has remained elusive. Previous studies suggest that 5-HT can activate intracellular small GTPas...

    Ramona Al-Zoairy, Michael T. Pedrini, Mohammad Imran Khan, Julia Engl, Alexander Tschoner, Christoph Ebenbichler, Gerhard Gstraunthaler, Karin Salzmann, Rania Bakry and Andreas Niederwanger

    Diabetology & Metabolic Syndrome 2017 9:1

    Published on: 3 January 2017

  12. Research

    CML/RAGE signal induces calcification cascade in diabetes

    Vascular calcification is a significant predictor of coronary heart disease events, stroke, and lower-limb amputation. Advanced glycation end-products (AGEs) play a key role in the development of vascular calc...

    Zhongqun Wang, Lihua Li, Rui Du, Jinchuan Yan, Naifeng Liu, Wei Yuan, Yicheng Jiang, Suining Xu, Fei Ye, Guoyue Yuan, Baohai Zhang and Peijing Liu

    Diabetology & Metabolic Syndrome 2016 8:83

    Published on: 28 December 2016

  13. Research

    Diabetes self-management education after pre-selection of patients: design of a randomised controlled trial

    Many self-management programs have been developed so far. Their effectiveness varies. The program ‘Beyond Good Intentions’ (BGI) is based on proactive coping and has proven to be (cost-) effective in achieving...

    Rimke C. Vos, Nathalie W. D. Eikelenboom, Maarten Klomp, Rebecca K. Stellato and Guy E. H. M. Rutten

    Diabetology & Metabolic Syndrome 2016 8:82

    Published on: 20 December 2016

  14. Research

    Impact of a 6-month treatment with intragastric balloon on body composition and psychopathological profile in obese individuals with metabolic syndrome

    The aim of this study was to investigate the effects of a 6-month treatment with intragastric balloon (IGB) on body composition and depressive/anxiety symptoms in obese individuals with metabolic syndrome (MS).

    Erika P. Guedes, Eduardo Madeira, Thiago T. Mafort, Miguel Madeira, Rodrigo O. Moreira, Laura Maria C. Mendonça, Amélio F. Godoy-Matos, Agnaldo J. Lopes and Maria Lucia F. Farias

    Diabetology & Metabolic Syndrome 2016 8:81

    Published on: 19 December 2016

  15. Research

    Association of diabetic vascular complications with poor sleep complaints

    Literatures reported that poor sleep complaints were associated with a great deal of health outcomes. However, there are few studies on the association of poor sleep complaints with diabetic vascular complicat...

    Ling-Ling Meng, Ying Liu, Rui-Na Geng, Yun-Zhao Tang and Dai-Qing Li

    Diabetology & Metabolic Syndrome 2016 8:80

    Published on: 8 December 2016

  16. Review

    Obesity and hypertensive heart disease: focus on body composition and sex differences

    There is evidence that hypertension is frequently associated with overweight/obesity even in kids and adolescents. Either conditions influence development of left ventricular (LV) hypertrophy (LVH), through di...

    Giovanni de Simone, Costantino Mancusi, Raffaele Izzo, Maria Angela Losi and L. Aldo Ferrara

    Diabetology & Metabolic Syndrome 2016 8:79

    Published on: 30 November 2016

  17. Research

    Accumulation of intestinal tissue 3-deoxyglucosone attenuated GLP-1 secretion and its insulinotropic effect in rats

    Our recent findings support the idea that 3-deoxyglucosone (3DG), a dietary composition, has been suggested as an independent factor for the development of prediabetes. Secretion of glucagon-like peptide-1 (GL...

    Lurong Zhang, Xiudao Song, Liang Zhou, Guoqiang Liang, Heng Xu, Fei Wang, Fei Huang and Guorong Jiang

    Diabetology & Metabolic Syndrome 2016 8:78

    Published on: 29 November 2016

  18. Research

    Relationship between vitamin D status, glycemic control and cardiovascular risk factors in Brazilians with type 2 diabetes mellitus

    Determine the prevalence and identify predictors of hypovitaminosis D in patients with type 2 diabetes mellitus (T2DM); 2) correlate vitamin D levels with variables indicative of glycemic control and cardiovas...

    Maria Creusa Rolim, Bárbara Mendes Santos, Gildasio Conceição and Paulo Novis Rocha

    Diabetology & Metabolic Syndrome 2016 8:77

    Published on: 16 November 2016

  19. Research

    Spermatozoal cell death-inducing DNA fragmentation factor-α-like effector A (CIDEA) gene expression and DNA fragmentation in infertile men with metabolic syndrome and normal seminogram

    This is the first study to investigate spermatozoal cell death-inducing DNA fragmentation factor-α-like effector A (CIDEA) gene expression and DNA fragmentations in the spermatozoa of men diagnosed with metabo...

    Ayman Z. Elsamanoudy, Hussein Abdelaziz Abdalla, Mohammed Hassanien and Mohammad A. Gaballah

    Diabetology & Metabolic Syndrome 2016 8:76

    Published on: 16 November 2016

  20. Research

    Hypoadiponectinemia and the presence of metabolic syndrome in patients with chronic kidney disease: results from the KNOW-CKD study

    In patients with chronic kidney disease, metabolic syndrome has been demonstrated to be the culprit behind diverse complications. Adiponectin is known to have anti-atherogenic and cardio-protective effects. Me...

    Chang-Yun Yoon, Yung Ly Kim, Seung Hyeok Han, Tae-Hyun Yoo, Su-Ah Sung, Woo-kyung Chung, Dong-Wan Chae, Yong-Soo Kim, Curie Ahn and Kyu Hun Choi

    Diabetology & Metabolic Syndrome 2016 8:75

    Published on: 14 November 2016

  21. Research

    Adipose tissue dysfunction increases fatty liver association with pre diabetes and newly diagnosed type 2 diabetes mellitus

    To evaluate the role of adipose tissue function on the association of fatty liver (FL) with impaired fasting glucose (IFG) or newly diagnosed type 2 diabetes mellitus (nT2D).

    Esteban Jorge-Galarza, Aida Medina-Urrutia, Rosalinda Posadas-Sánchez, Carlos Posadas-Romero, Guillermo Cardoso-Saldaña, Gilberto Vargas-Alarcón, Nacú Caracas-Portilla, Carmen González-Salazar, Margarita Torres-Tamayo and Juan Gabriel Juárez-Rojas

    Diabetology & Metabolic Syndrome 2016 8:73

    Published on: 11 November 2016

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The official journal of the Brazilian Diabetes Society.

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