Skip to main content

Table 3 ORs and 95%CIs for the associations between IR-related features and cognitive performance

From: Insulin resistance-related features are associated with cognitive decline: a cross-sectional study in adult patients with type 1 diabetes

Components

Having low global cognitive performance

Having low memory performance

Having low executive function performance

Having low sustained attention performance

Having IR-related features†

4.07 (1.44, 9.62) **

6.03 (1.38, 26.39) *

2.74 (1.06, 7.08) *

3.78 (1.20, 11.92) *

Having 1 IR-related feature†

3.45 (1.04, 11.44) *

3.32 (0.64, 17.37)

2.34 (0.79, 6.91)

2.11 (0.54, 8.20)

Having ≥ 2 IR-related features†

4.86 (1.36, 17.39) *

13.35 (2.10, 84.94) **

3.30 (1.01, 10.86) *

6.86 (1.66, 28.40) **

Overweight/obesity/central obesity

1.72 (0.39, 7.54)

3.89 (0.53, 28.32)

4.97 (1.07, 23.19) *

1.74 (0.36, 8.33)

Hypertension

1.55 (0.42, 5.71)

1.73 (0.34, 8.84)

0.90 (0.26, 3.16)

0.56 (0.11, 2.75)

Atherogenic dyslipidemia

7.08 (1.96, 25.55) **

5.49 (1.03, 29.33) *

3.52 (1.15, 10.84) *

3.58 (0.97, 13.19)

eIS ≤ 4.66 mg/kg/min

3.57 (1.23, 10.34) *

13.89 (2.48, 77.84) **

1.64 (0.65, 4.14)

3.31 (1.04, 10.48) *

  1. Logistic regression analyses were performed to evaluate the associations between IR-related features and cognitive performance, adjusted for age, gender, age of onset, hyperglycemia exposure score, history of DK/DKA, hypoglycemia episodes of the previous month, diabetic complications, years of education, depression and anxiety scores. ORs: odds ratios; CIs: confidence intervals; IR: insulin resistance; eIS: estimated insulin sensitivity. †: compared to having no IR-related features; *: p < 0.05, **: p < 0.01, ***: p < 0.001
Back to article page

Diabetology & Metabolic Syndrome

ISSN: 1758-5996

Contact us