Table 1 Baseline characteristics in type 2 diabetic patients
From: Association between serum PCSK9 and coronary heart disease in patients with type 2 diabetes mellitus
| Â | Total | CHD group | Non-CHD group | p value |
|---|---|---|---|---|
Clinical characteristics | Â | Â | Â | Â |
N (%) | 2984 | 1776 (59.52%) | 1208 (40.48%) | – |
Age (years) | 57.48 ± 9.93 | 57.81 ± 9.74 | 56.99 ± 10.19 | 0.222 |
Male (%) | 1732 (58.04%) | 1046 (58.90%) | 686 (56.78%) | 0.252 |
BMI (kg/m2) | 25.23 ± 3.07 | 25.06 ± 2.90 | 25.48 ± 3.31 | 0.131 |
Hypertension (%) | 2084 (69.53%) | 1252 (70.50%) | 832 (68.87%) | 0.344 |
Smoking (%) | 838 (28.08%) | 481 (27.08%) | 357 (29.55%) | 0.141 |
Alcohol consumption (%) | 887 (29.73%) | 541 (30.46%) | 346 (28.64%) | 0.286 |
Family history of CHD (%) | 851 (28.52%) | 531 (29.90%) | 320 (26.49%) | 0.043 |
Family history of MD (%) | 1135 (38.04%) | 655 (36.88%) | 480 (39.73%) | 0.115 |
Laboratory variables | Â | Â | Â | Â |
FBG (mmol/L) | 7.69 ± 1.16 | 7.73 ± 1.21 | 7.64 ± 1.08 | 0.219 |
HbA1c (%) | 7.52 ± 1.10 | 7.55 ± 1.15 | 7.48 ± 1.02 | 0.367 |
ApoB (mg/dL) | 85.10 (26.85) | 87.00 (36.60) | 84.16 (20.16) | 0.004 |
ApoA1 (mg/dL) | 144.1 (37.55) | 142.50 (41.50) | 145.65 (31.58) | 0.014 |
Total cholesterol (mmol/L) | 4.44 (1.34) | 4.46 (1.72) | 4.41 (0.98) | 0.009 |
Triglycerides (mmol/L) | 1.32 (0.88) | 1.32 (0.82) | 1.32 (0.94) | 0.395 |
HDL-C (mmol/L) | 1.14 (0.35) | 1.13 (0.30) | 1.15 (0.39) | 0.005 |
LDL-C (mmol/L) | 2.73 (0.94) | 2.79 (1.37) | 2.71 (0.67) | 0.011 |
Lp(a) (nmol/L) | 39.24 (39.77) | 40.51 (48.21) | 36.99 (33.45) | 0.001 |
hs-CRP (mg/L) | 1.38 (1.69) | 1.57 (1.80) | 1.23 (1.56) | 0.386 |
HCY (umol/L) | 11.65 (7.69) | 11.77 (8.51) | 11.45 (6.60) | 0.091 |
sdLDL-C (mmol/L) | 0.74 (0.37) | 0.76 (0.47) | 0.71 (0.31) | 0.005 |
PCSK9 (ng/mL) | 521.98 (209.78) | 554.62 (265.11) | 496.86 (129.05) | < 0.001 |