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Table 8 Stratified associations between non-HDL-c/HDL-c ratio and reversion to normoglycemia in people with IFG in prespecified and exploratory subgroups

From: Association between non-high-density lipoprotein to high-density lipoprotein ratio and reversion to normoglycemia in people with impaired fasting glucose: a 5-year retrospective cohort study

Characteristic

No of participants

HR (95%CI)

P value

P for interaction

Age(years)

 

0.70 (0.67, 0.74)

 

0.5084

  < 45

5258

0.70 (0.67, 0.74)

 < 0.0001

 

  ≥ 45

9966

0.72 (0.69, 0.75

 < 0.0001

 

Gender

   

0.5175

 Male

9843

0.71 (0.68, 0.74)

 < 0.0001

 

 Female

5381

0.72 (0.68, 0.76)

 < 0.0001

 

BMI (kg/m2)

   

0.5877

  < 18.5

257

0.76 (0.57, 1.01)

0.0590

 

  ≥ 18.5, < 24

5972

0.69 (0.65, 0.73)

 < 0.0001

 

  ≥ 24, < 28

6575

0.71 (0.67, 0.75)

 < 0.0001

 

  ≥ 28

2420

0.74 (0.67, 0.80)

 < 0.0001

 

SBP (mmHg)

    

  < 140

11809

0.71 (0.68, 0.73)

 < 0.0001

 

DBP (mmHg)

    

  < 90

12969

0.71 (0.68, 0.73)

 < 0.0001

 

  ≥ 90

2255

0.73 (0.67, 0.79)

 < 0.0001

 

TG (mmol/L)

    

  < 1.7

9292

0.68 (0.65, 0.72)

 < 0.0001

 

  ≥ 1.7

5932

0.76 (0.73, 0.80)

 < 0.0001

 

FPG (mmol/L)

   

0.2422

  < 6.1

11060

0.71 (0.69, 0.74)

 

 < 0.0001

  ≥ 6.1

4164

0.68 (0.63, 0.73)

 

 < 0.0001

  1. Note 1: Above model adjusted for gender, age, BMI, SBP, DBP, FPG, BUN, Scr, TG, LDL-c, ALT, AST, family history of diabetes, smoking and drinking status
  2. Note 2: In each case, the model is not adjusted for the stratification variable
  3. HR Hazard ratios, CI confidence, Ref reference