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Table 6 Correlation of leptin and βHB levels change (pre vs post fasting) with the change in clinico-laboratory parameters

From: Effect of intermittent fasting on lipid biokinetics in obese and overweight patients with type 2 diabetes mellitus: prospective observational study

Characteristic

Change

Leptin

 

BHB

 

rs

p-value

rs

p-value

Serum Leptin (ng/ml)

–

–

0.050

0.792

B hydroxybutyrate (mmol/L)

0.050

0.792

–

–

Age

0.079

0.677

− 0.201

0.287

Diabetes duration (years)

− 0.210

0.266

− 0.227

0.227

Fasting duration (days)

0.347

0.060

0.315

0.090

Body weight (kg)

0.120

0.526

0.170

0.369

BMI (kg/m2)

0.153

0.419

0.143

0.451

Waist circumference (cm)

0.128

0.501

0.183

0.334

Hip circumference (cm)

0.185

0.329

− 0.008

0.967

Waist/hip ratio

− 0.013

0.944

0.270

0.149

FPG (mg/dl)

− 0.352

0.056

0.100

0.598

S. creatinine (mg/dl)

− 0.028

0.883

0.106

0.578

Hemoglobin A1c

− 0.168

0.374

− 0.126

0.508

AST (IU/L)

0.205

0.277

0.243

0.196

ALT (IU/L)

0.334

0.071

− 0.155

0.415

AST/ALT ratio

− 0.120

0.526

0.251

0.181

S. cholesterol (mg/dl)

0.167

0.376

− 0.044

0.816

Triglycerides (mg/dl)

0.012

0.952

0.106

0.976

LDL-C (mg/dl)

0.385

0.035

− 0.216

0.252

HDL-C (mg/dl)

− 0.215

0.938

0.117

0.537

High sensitive CRP (mg/L)

− 0.244

0.194

0.103

0.589

  1. Bold values mentioned in these tables means that p value were ≤ 0.050 (statistically significant results of the corresponding used tests)
  2. rs Spearman’s correlation coefficient. BMI Body mass index. FPG fasting plasma glucose. AST aspartate aminotransferase. ALT alanine transaminase. LDL-C low density lipoprotein-cholesterol. HDL-C high density lipoprotein-cholesterol. CRP C-reactive protein
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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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