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Table 2 Significant changed pathways of combined analysis of proteins and metabolites by KEGG

From: Effect of dapagliflozin on proteomics and metabolomics of serum from patients with type 2 diabetes

NO

Pathway name

Class

Names

q value

1

Glycolysis/gluconeogenesis

Protein

Fructose-1,6-bisphosphatase 1(FBP1)

4.71E−02

Protein

Fructose-bisphosphate aldolase B(ALDOB)

2.36E−06

Protein

4-trimethylaminobutyraldehyde dehydrogenase (ALDH9A1)

2.24E−02

Metabolite

Hexose

2.29E−06

2

Pentose phosphate pathway

Protein

Fructose-1,6-bisphosphatase 1(FBP1)

4.71E−02

Protein

Fructose-bisphosphate aldolase B(ALDOB)

2.36E−06

Metabolite

Gluconolactone

6.90E−07

Metabolite

Ribose

1.58E−06

Metabolite

Hexose

2.29E−06

  1. q value is the FDR adjusted p value and calculated from the enrichment analysis