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Table 2 Characteristics of high risk participants by SBEM and ST1RE

From: A comparative study of cardiovascular risk stratification methods in type 1 diabetes mellitus patients

 

SBEM

(n = 67)

ST1RE

(n = 14)

p-value

Age (years)

38.1 (± 10.7)

50.3 (± 9.9)

0.0002*

Sex

  

1.000

Male

34.9 (23)

30.8 (4)

 

Female

65.1 (43)

69.2 (9)

 

Diabetes duration (years)

27.0 (19.0; 32.0)

34.0 (31.0; 42.0)

0.029*

Age of T1DM onset (years)

11.0 (4.0; 17.0)

16.0 (10.0; 28.0)

0.065**

Early onset T1DM (1–10 years of age)

44.8 (30)

28.6 (4)

0.375

Late onset T1DM (> 10 years of age)

55.2 (37)

71.4 (10)

 

BMI (kg/m2)

23.4 (21.4; 28.0)

21.5 (20.4; 23.2)

0.055**

HbA1c (%)

8.6 (7.6; 10.0)

9.4 (7.8; 10.8)

0.209**

SBP (mmHg)

122.0 (110.0; 130.0)

133.0 (128.0; 144.0)

0.004**

DBP (mmHg)

80.0 (70.0; 80.0)

80.0 (78.0; 82.0)

0.226**

LDL-cholesterol (mg/dl)

90.0 (70.4; 113.4)

91.1 (71.2; 112.0)

0.925**

eGFR (CKD-EPI) (ml/min/1.73 m2

99.0 (72.0; 114.0)

69.5 (33.0; 79.0)

0.0005**

Serum creatinin (mg/dL)

0.85 (0.74; 1.03)

1.04 (0.92; 1.84)

0.0035**

Albumin-Creatinin Ratio (mg/g)

  

0.004

Normal

52.2 (35)

7.1 (1)

 

Microalbuminúria

23.9 (16)

42.9 (6)

 

Macroalbuminúria

23.9 (16)

50.0 (7)

 

Microvascular complications (%)

83.6 (56)

100.0 (14)

0.197

Nephropathy (%)

55.2 (37)

92.9 (13)

0.013

Retinopathy (%)

74.6 (50)

92.9 (13)

0.175

Neuropathy (%)

13.4 (9)

28.6 (4)

0.224

Treatments

   

Statins

52.2 (35)

71.4 (10)

0.244

ACE inhibitor or ARB

67.2 (45)

78.6 (11)

0.532

AAS

7.5 (5)

28.6 (4)

0.044

Physical activity

11.9 (8)

14.3 (2)

0.681

Smoking

4.8 (3)

7.7 (1)

0.541

  1. Data are expressed as mean ± standard deviation or median (P25;P75) or as a percentage (%); SBP systolic blood pressure; DBP diastolic blood pressure; eGFR estimated glomerular filtration rate; BMI body mass index; T1DM type 1 diabetes mellitus; HBA1c glycated hemoglobin. *T-Student test, **Mann-Whitney test, Fisher´s Exact test were used.