From: Remnant cholesterol and severity of nonalcoholic fatty liver disease
Variables | Quartile 1 (n = 1,536) | Quartile 2 (n = 1,540) | Quartile 3 (n = 1,479) | Quartile 4 (n = 1,498) | P value |
---|---|---|---|---|---|
Female, % | 56.38 | 46.04 * | 36.58 †§ | 28.50 ‡ || ¶ | < 0.001 |
Age, year | 49.69 (12.51) | 50.96 (11.31) * | 51.53 (10.42) †§ | 52.07 (10.02) ‡ || ¶ | < 0.001 |
Body mass index, kg/m2 | 22.64 (2.94) | 23.73 (3.01) * | 24.56 (2.97) †§ | 25.55 (3.01) ‡ || ¶ | < 0.001 |
Current smoker, % | 13.48 | 16.88 * | 24.75 †§ | 30.77 ‡ || ¶ | < 0.001 |
Systolic blood pressure, mmHg | 117.93 (16.83) | 122.62 (17.29) * | 123.92 (16.79) †§ | 126.11 (16.08) ‡ || ¶ | < 0.001 |
Diastolic blood pressure, mmHg | 69.55 (11.13) | 72.95 (11.11) * | 73.95 (11.03) †§ | 75.98 (10.72) ‡ || ¶ | < 0.001 |
Serum uric acid, µmol/L | 289.03 (71.58) | 318.65 (80.43) * | 339.63 (82.40) †§ | 367.94 (83.28) ‡ || ¶ | < 0.001 |
Total cholesterol, mmol/L | 4.29 (0.77) | 4.66 (0.76) * | 5.00 (0.84) †§ | 5.41 (0.97) ‡ || ¶ | < 0.001 |
Triglyceride, mmol/L | 0.83 (0.25) | 1.16 (0.33) * | 1.56 (0.43) †§ | 2.88 (1.86) ‡ || ¶ | < 0.001 |
HDL-C, mmol/L | 1.51 (0.36) | 1.33 (0.32) * | 1.20 (0.28) †§ | 1.03 (0.24) ‡ || ¶ | < 0.001 |
LDL-C, mmol/L | 2.36 (0.62) | 2.68 (0.62) * | 2.95 (0.71) †§ | 3.00 (0.87) ‡ || ¶ | < 0.001 |
Fasting plasma glucose, mmol/L | 4.75 (0.83) | 4.92 (1.03) * | 5.00 (1.18) †§ | 5.23 (1.56) ‡ || ¶ | < 0.001 |
Glycated hemoglobin A1c, % | 5.64 (0.59) | 5.74 (0.74) * | 5.82 (0.76) †§ | 5.97 (1.03) ‡ || ¶ | < 0.001 |
Remnant cholesterol, mmol/L | 0.43 (0.10) | 0.65 (0.05) * | 0.85 (0.07) †§ | 1.37 (0.56) ‡ || ¶ | < 0.001 |
γ-glutamyl transpeptidase, U/L | 15.00 [12.00, 22.00] | 19.00 [14.00, 28.00] * | 24.00 [16.00, 36.00] †§ | 32.00 [21.00, 51.00] ‡ || ¶ | < 0.001 |
Severity of hepatic steatosis, % |  |  |  |  | < 0.001 |
 Mild steatosis | 21.29 | 32.14 * | 40.50 †§ | 54.14 ‡ || ¶ |  |
 Moderate-to-severe steatosis | 1.89 | 3.64 * | 6.42 †§ | 11.68 ‡ || ¶ |  |
 Overall steatosis | 23.18 | 35.78 * | 46.92 †§ | 65.82 ‡ || ¶ |  |