Table 3 The HRs of all-cause mortality or CVD mortality in the participants with metabolic syndrome in subgroup analyses

Subgroup

Total

Event(%)

HR(95%CI)

P for interaction

Event(%)

HR(95%CI)

P for interaction

Gender = Female

0.726

0.115

 LTL Tertile3

373

101 (27.1)

1(Ref)

19 (5.1)

1(Ref)

 LTL Tertile2

329

120 (36.5)

1.01 (0.77 ~ 1.33)

32 (9.7)

1.46 (0.81 ~ 2.62)

 LTL Tertile1

307

162 (52.8)

1.19 (0.92 ~ 1.55)

47 (15.3)

1.61 (0.92 ~ 2.81)

Trend test

1009

383 (38)

1.1 (0.96 ~ 1.25)

98 (9.7)

1.24 (0.95 ~ 1.62)

Gender = Male

 LTL Tertile3

287

94 (32.8)

1(Ref)

33 (11.5)

1(Ref)

 LTL Tertile2

331

125 (37.8)

0.91 (0.69 ~ 1.19)

39 (11.8)

0.82 (0.51 ~ 1.31)

 LTL Tertile1

353

217 (61.5)

1.16 (0.9 ~ 1.5)

61 (17.3)

0.91 (0.58 ~ 1.41)

Trend test

971

436 (44.9)

1.1 (0.97 ~ 1.25)

133 (13.7)

0.97 (0.77 ~ 1.21)

Chronic kidney disease = no

0.659

 LTL Tertile3

537

128 (23.8)

1(Ref)

33 (6.1)

1(Ref)

 LTL Tertile2

491

145 (29.5)

0.92 (0.72 ~ 1.17)

37 (7.5)

0.86 (0.53 ~ 1.39)

 LTL Tertile1

435

197 (45.3)

1.15 (0.91 ~ 1.45)

54 (12.4)

1.09 (0.69 ~ 1.72)

Trend test

1463

470 (32.1)

1.08 (0.96 ~ 1.22)

124 (8.5)

1.06 (0.84 ~ 1.34)

Chronic kidney disease = yes

 LTL Tertile3

123

67 (54.5)

1(Ref)

19 (15.4)

1(Ref)

 LTL Tertile2

169

100 (59.2)

1.2 (0.87 ~ 1.65)

34 (20.1)

1.61 (0.89 ~ 2.91)

 LTL Tertile1

225

182 (80.9)

1.32 (0.98 ~ 1.79)

54 (24)

1.4 (0.8 ~ 2.44)

Trend test

517

349 (67.5)

1.14 (0.99 ~ 1.32)

107 (20.7)

1.12 (0.87 ~ 1.45)

Corory heart disease = no

0.351

 LTL Tertile3

631

174 (27.6)

1(Ref)

43 (6.8)

1(Ref)

 LTL Tertile2

623

222 (35.6)

1 (0.82 ~ 1.22)

59 (9.5)

1.07 (0.71 ~ 1.59)

 LTL Tertile1

619

346 (55.9)

1.24 (1.02 ~ 1.49)

91 (14.7)

1.21 (0.83 ~ 1.77)

Trend test

1873

742 (39.6)

1.12 (1.02 ~ 1.24)

193 (10.3)

1.11 (0.92 ~ 1.33)

Corory heart disease = yes

 LTL Tertile3

29

21 (72.4)

1(Ref)

9 (31)

1(Ref)

 LTL Tertile2

37

23 (62.2)

0.69 (0.36 ~ 1.32)

12 (32.4)

0.85 (0.34 ~ 2.14)

 LTL Tertile1

41

33 (80.5)

1.12 (0.62 ~ 2.03)

17 (41.5)

1.39 (0.58 ~ 3.33)

Trend test

107

77 (72)

1.07 (0.79 ~ 1.47)

38 (35.5)

1.21 (0.77 ~ 1.91)

DM = yes

0.207

0.241

 LTL Tertile3

126

66 (52.4)

1(Ref)

24 (19)

1(Ref)

 LTL Tertile2

150

74 (49.3)

0.87 (0.62 ~ 1.23)

21 (14)

0.71 (0.39 ~ 1.3)

 LTL Tertile1

160

113 (70.6)

1.02 (0.74 ~ 1.41)

37 (23.1)

0.98 (0.57 ~ 1.7)

Trend test

436

253 (58)

1.02 (0.87 ~ 1.2)

82 (18.8)

1.01 (0.76 ~ 1.34)

DM = no

 LTL Tertile3

477

126 (26.4)

1(Ref)

28 (5.9)

1(Ref)

 LTL Tertile2

483

169 (35)

0.98 (0.78 ~ 1.24)

50 (10.4)

1.23 (0.77 ~ 1.97)

 LTL Tertile1

489

266 (54.4)

1.25 (1 ~ 1.56)

71 (14.5)

1.33 (0.84 ~ 2.1)

Trend test

1449

561 (38.7)

1.13 (1.02 ~ 1.27)

149 (10.3)

1.14 (0.92 ~ 1.42)

Hypertension = no

0.846

0.689

 LTL Tertile3

235

43 (18.3)

1(Ref)

10 (4.3)

1(Ref)

 LTL Tertile2

201

42 (20.9)

0.88 (0.57 ~ 1.37)

10 (5)

0.99 (0.4 ~ 2.46)

 LTL Tertile1

165

63 (38.2)

1.12 (0.75 ~ 1.7)

12 (7.3)

0.96 (0.39 ~ 2.37)

Trend test

601

148 (24.6)

1.07 (0.87 ~ 1.32)

32 (5.3)

0.98 (0.63 ~ 1.54)

Hypertension = yes

 LTL Tertile3

425

152 (35.8)

1(Ref)

42 (9.9)

1(Ref)

 LTL Tertile2

459

203 (44.2)

0.97 (0.78 ~ 1.2)

61 (13.3)

1.02 (0.68 ~ 1.52)

 LTL Tertile1

495

316 (63.8)

1.22 (1 ~ 1.5)

96 (19.4)

1.22 (0.84 ~ 1.78)

Trend test

1379

671 (48.7)

1.12 (1.02 ~ 1.24)

199 (14.4)

1.12 (0.93 ~ 1.35)

Hyperlipidemia = no

0.857

0.987

 LTL Tertile3

105

37 (35.2)

1(Ref)

10 (9.5)

1(Ref)

 LTL Tertile2

86

34 (39.5)

0.83 (0.49 ~ 1.4)

10 (11.6)

1.06 (0.34 ~ 3.33)

 LTL Tertile1

100

59 (59)

1.24 (0.79 ~ 1.96)

15 (15)

1.18 (0.42 ~ 3.31)

Trend test

291

130 (44.7)

1.15 (0.91 ~ 1.45)

35 (12)

1.09 (0.66 ~ 1.8)

Hyperlipidemia = yes

 LTL Tertile3

555

158 (28.5)

1(Ref)

42 (7.6)

1(Ref)

 LTL Tertile2

574

211 (36.8)

0.97 (0.78 ~ 1.19)

61 (10.6)

1 (0.67 ~ 1.49)

 LTL Tertile1

560

320 (57.1)

1.17 (0.96 ~ 1.43)

93 (16.6)

1.16 (0.79 ~ 1.7)

Trend test

1689

689 (40.8)

1.1 (0.99 ~ 1.21)

196 (11.6)

1.09 (0.9 ~ 1.31)

Stroke = no

0.655

0.218

LTL Tertile3

644

183 (28.4)

1(Ref)

46 (7.1)

1(Ref)

LTL Tertile2

632

226 (35.8)

0.97 (0.8 ~ 1.18)

67 (10.6)

1.11 (0.76 ~ 1.62)

LTL Tertile1

629

351 (55.8)

1.18 (0.98 ~ 1.42)

100 (15.9)

1.21 (0.84 ~ 1.73)

Trend test

1905

760 (39.9)

1.1 (1 ~ 1.21)

213 (11.2)

1.1 (0.92 ~ 1.31)

Stroke = yes

 LTL Tertile3

16

12 (75)

1(Ref)

6 (37.5)

1(Ref)

 LTL Tertile2

28

19 (67.9)

0.91 (0.32 ~ 2.52)

4 (14.3)

0.41 (0.04 ~ 4.26)

 LTL Tertile1

31

28 (90.3)

1.74 (0.66 ~ 4.58)

8 (25.8)

1.33 (0.22 ~ 8.09)

Trend test

75

59 (78.7)

1.46 (0.93 ~ 2.31)

18 (24)

1.32 (0.53 ~ 3.26)

Cancer = no

0.425

0.138

 LTL Tertile3

598

164 (27.4)

1(Ref)

44 (7.4)

1(Ref)

 LTL Tertile2

582

199 (34.2)

0.91 (0.74 ~ 1.13)

55 (9.5)

0.86 (0.57 ~ 1.29)

 LTL Tertile1

561

300 (53.5)

1.14 (0.93 ~ 1.39)

89 (15.9)

1.12 (0.77 ~ 1.64)

Trend test

1741

663 (38.1)

1.08 (0.98 ~ 1.2)

188 (10.8)

1.09 (0.9 ~ 1.32)

Cancer = yes

 LTL Tertile3

62

31 (50)

1(Ref)

8 (12.9)

1(Ref)

 LTL Tertile2

78

46 (59)

1.21 (0.75 ~ 1.97)

16 (20.5)

1.75 (0.69 ~ 4.42)

 LTL Tertile1

99

79 (79.8)

1.49 (0.95 ~ 2.33)

19 (19.2)

1.53 (0.62 ~ 3.78)

Trend test

239

156 (65.3)

1.22 (0.98 ~ 1.52)

43 (18)

1.18 (0.77 ~ 1.81)