17-year follow-up of association between telomere length and all-cause mortality, cardiovascular mortality in individuals with metabolic syndrome: results from the NHANES database prospective cohort study

Table 2 The HRs of all-cause mortality or CVD mortality in the participants with metabolic syndrome

Variable	Total	Event(%)	Model 1	P value	Model 2	P value	Model 3	P value	Model 4	P value
All-cause mortality
LTL Tertile3	660	195 (29.5)	1(Ref)		1(Ref)		1(Ref)		1(Ref)
LTL Tertile2	660	245 (37.1)	1.35 (1.12 ~ 1.63)	0.002	1.03 (0.85 ~ 1.24)	0.788	1.03 (0.85 ~ 1.25)	0.769	1 (0.83 ~ 1.21)	0.999
LTL Tertile1	660	379 (57.4)	2.43 (2.05 ~ 2.89)	< 0.001	1.43 (1.19 ~ 1.7)	< 0.001	1.4 (1.17 ~ 1.68)	< 0.001	1.35 (1.12 ~ 1.61)	0.001
Trend test	1980	819 (41.4)	1.58 (1.45 ~ 1.73)	< 0.001	1.21 (1.11 ~ 1.33)	< 0.001	1.2 (1.1 ~ 1.32)	< 0.001	1.18 (1.08 ~ 1.29)	< 0.001
Cardiovascular mortality
LTL Tertile3	660	52 (7.9)	1(Ref)		1(Ref)		1(Ref)		1(Ref)
LTL Tertile2	660	71 (10.8)	1.47 (1.03 ~ 2.1)	0.036	1.09 (0.76 ~ 1.57)	0.626	1.11 (0.77 ~ 1.59)	0.589	1.1 (0.77 ~ 1.59)	0.594
LTL Tertile1	660	108 (16.4)	2.58 (1.85 ~ 3.59)	< 0.001	1.46 (1.04 ~ 2.04)	0.03	1.44 (1.02 ~ 2.03)	0.038	1.41 (1 ~ 2)	0.049
Trend test	1980	231 (11.7)	1.62 (1.38 ~ 1.92)	< 0.001	1.22 (1.03 ~ 1.45)	0.02	1.21 (1.02 ~ 1.44)	0.028	1.2 (1.01 ~ 1.42)	0.037

Model 1: Crude Model
Model 2: Adjusted for age and gender
Model 3: Adjusted for age, gender, race, marital status, body mass index, alcohol user, smoking status, and annual family income
Model 4: Adjusted for age, gender, race, marital status, body mass index, alcohol user, smoking status, annual family income, congestive heart failure, coronary heart disease, chronic kidney disease, chronic obstructive pulmonary disease (COPD), diabetes mellitus, hypertension, hyperlipidemia, and stroke

ISSN: 1758-5996