From: Metabolic syndrome and transaminases: systematic review and meta-analysis
Certainty assessment | No. of subjects | Size of the effect | Quality of evidence | |||||||
---|---|---|---|---|---|---|---|---|---|---|
No. of studies | Study design | Risk of bias | Inconsistency | Indirect evidence | Imprecision | Other considerations | MetS+ | MetS- | Mean difference (95% CI) | |
ALT Meta-analysis | ||||||||||
n = 17 | Observational studies | serious | Very serious | It is not serious | It is not serious | dose-response gradient | 76.686 | 201.855 | 7.13 (5.73–8.54) | ⨁◯◯◯ Very low |
AST Meta-analysis | ||||||||||
n = 15 | Observational studies | serious | Very serious | It is not serious | It is not serious | dose-response gradient | 74.526 | 196.212 | 2.68 (1.82–3.54) | ⨁◯◯◯ Very low |
GGT Meta-analysis | ||||||||||
n = 5 | Observational studies | serious | Very serious | It is not serious | It is not serious | dose-response gradient | 13.302 | 42.431 | 11.2 (7.11–15.29) | ⨁◯◯◯ Very low |