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Table 4 Logistic regression analysis for the association between the thyroid parameters quartiles and GDM in pre-pregnancy non-obese and obese subgroups

From: Maternal pre-pregnancy obesity modifies the association between first-trimester thyroid hormone sensitivity and gestational Diabetes Mellitus: a retrospective study from Northern China

 

Q1

Q2

Q3

Q4

 

Variable (1SD)

OR (95% CI)

OR (95% CI)

OR (95% CI)

OR (95% CI)

P for trend

TFQI

     

Non-obese

Ref.

0.955 (0.567, 1.608)

1.733 (1.067, 2.816)*

1.981 (1.224, 3.207)**

0.001

Obese

Ref.

0.926 (0.332, 2.581)

0.298 (0.098, 0.907)*

0.131 (0.036, 0.472)**

< 0.001

PTFQI

     

Non-obese

Ref.

0.774 (0.455,1.318)

1.776 (1.111, 2.840)*

1.738 (1.078, 2.803)*

0.002

Obese

Ref.

1.091 (0.386, 3.086)

0.463 (0.149, 1.441)

0.171 (0.046, 0.631)**

0.002

TSHI

     

Non-obese

Ref.

1.099 (0.667, 1.812)

1.335( 0.817, 2.182)

1.860 (1.156, 2.994)*

0.008

Obese

Ref.

1.701 (0.553, 5.231)

0.488 (0.139, 1.709)

0.252 (0.069, 0.927)*

0.007

TT4RI

     

Non-obese

Ref.

1.036 (0.636, 1.689)

1.215 (0.751, 1.966)

1.554 (0.967, 2.497)#

0.045

Obese

Ref.

1.534 (0.506,4.655)

0.668 (0.212, 2.103)

0.253 (0.071, 0.897)*

0.003

  1. *P < 0.05, **P < 0.01, #P = 0.068
  2. Model was adjusted for age, parity, first-trimester TG, LDL-C, UA and eGFR.