Non-obese | Obese | |||||
---|---|---|---|---|---|---|
Variables | Non-GDM | GDM | P value | Non-GDM | GDM | P value |
N | 960 | 182 | Â | 125 | 43 | Â |
Age, years | 31.27 ± 3.46 | 32.93 ± 4.07 | < 0.001 | 31.97 ± 3.59 | 32.72 ± 4.12 | 0.255 |
Gestational week | 39.33 ± 1.28 | 38.91 ± 1.26 | < 0.001 | 38.99 ± 1.45 | 39.13 ± 0.85 | 0.553 |
pBMI (kg/m2) | 20.69 ± 2.05 | 21.31 ± 1.93 | < 0.001 | 27.37 ± 2.09 | 27.34 ± 2.10 | 0.936 |
Parity, n (%) | Â | Â | 0.048 | Â | Â | 0.363 |
≥ 1 | 186 (19.4%) | 47 (25.8%) |  | 35 (28.0%) | 9 (20.9%) |  |
0 | 774 (81.6%) | 135 (74.2%) | Â | 90 (72.0%) | 34 (79.1%) | Â |
Thyroid parameter | Â | Â | Â | Â | Â | Â |
FT3 (pmol/L) | 4.92 ± 0.48 | 4.94 ± 0.48 | 0.594 | 4.99 ± 0.51 | 5.01 ± 0.51 | 0.811 |
FT4 (pmol/L) | 16.15 ± 1.87 | 16.25 ± 1.96 | 0.515 | 15.95 ± 2.04 | 15.49 ± 1.88 | 0.197 |
TSH (mIU/mL ) | 1.17 (0.72,1.74) | 1.31 (0.81, 1.99) | 0.028 | 1.57 (1.00, 2.02) | 1.18 (0.87, 1.56) | 0.007 |
FT3/FT4 ratio | 0.307 ± 0.036 | 0.307 ± 0.036 | 0.903 | 0.315 ± 0.036 | 0.326 ± 0.042 | 0.102 |
TFQI | -0.01 ± 0.36 | 0.05 ± 0.36 | 0.024 | 0.06 ± 0.35 | -0.12 ± 0.26 | 0.001 |
PTFQI | -0.01 ± 0.35 | 0.06 ± 0.35 | 0.029 | 0.06 ± 0.33 | -0.09 ± 0.25 | 0.001 |
TSHI | 2.30 (1.82, 2.69) | 2.46 (1.99, 2.85) | 0.008 | 2.52 (2.20, 2.87) | 2.20 (1.96, 2.38) | < 0.001 |
TT4RI | 18.88 (11.53,27.27) | 21.11 (13.86,31.35) | 0.016 | 23.33 (16.28, 33.05) | 17.83 (14.89,23.65) | 0.001 |
TPO-Ab (U/L) | 30.00 (14.00, 41.70) | 30.90 (14.00, 41.10) | 0.726 | 30.10 (14.00, 41.00) | 32.20 (14.00,41.73) | 0.711 |
TG-Ab (U/L) | 16.70 (7.50, 27.00) | 15.60 (7.50, 26.00) | 0.215 | 17.90 (7.50, 30.73) | 7.50 (7.50, 30.83) | 0.305 |
Biochemistry parameter | Â | Â | Â | Â | Â | Â |
TG ( mg/dL ) | 79.74 (63.79, 101.00) | 95.69 (75.31, 121.38) | < 0.001 | 102.78 (80.18, 129.58) | 109.86 (90.82, 131.35) | 0.336 |
TC ( mg/dL ) | 157.56 ± 24.50 | 165.39 ± 28.82 | 0.001 | 162.96 ± 25.48 | 171.34 ± 27.58 | 0.074 |
HDL-C ( mg/dL ) | 59.17 (52.20, 67.67) | 59.75 (49.21, 66.51) | 0.407 | 51.43 (43.31, 59.94) | 52.59 (44.47, 59.26) | 0.926 |
LDL-C ( mg/dL ) | 86.23 (73.47, 100.16) | 94.16 (78.98 108.86) | < 0.001 | 99.00 (82.27, 119.20) | 106.92 (92.13, 125.48) | 0.052 |
AST (U/L) | 17.0 (15.0, 19.0) | 17.0 (15.0, 20.0) | 0.957 | 17.0 (15.0, 21.0) | 16.5 (15.0, 19.3) | 0.292 |
ALT (U/L) | 14.0 (11.0, 19.0) | 15.0 (12.0, 19.0) | 0.542 | 16.0 (13.8, 25.5) | 20.0 (15.0, 23.3) | 0.36 |
eGFR (mL/min per 1.73 | 139.34 (125.94, 153.30) | 137.19 (123.83, 148.53) | 0.227 | 133.47 (119.93, 148.22) | 128.76 (117.54, 137.86) | 0.069 |
m2 ) | ||||||
UA ( mg/dL ) | 3.56 (3.16, 4.10) | 3.87 (3.24, 4.42) | < 0.001 | 4.40 (3.59, 4.96) | 4.42 (3.71, 5.20) | 0.403 |
OGTT-FPG ( mg/dL ) | 75.62 ± 6.39 | 82.01 ± 11.01 | < 0.001 | 78.46 ± 7.79 | 88.95 ± 9.50 | < 0.001 |
OGTT-1hPPG ( mg/dL ) | 128.79 ± 24.53 | 172.58 ± 25.31 | < 0.001 | 136.73 ± 24.30 | 179.56 ± 28.28 | < 0.001 |
OGTT-2hPPG ( mg/dL ) | 114.07 ± 18.16 | 157.17 ± 23.98 | < 0.001 | 117.87 ± 18.08 | 160.51 ± 23.59 | < 0.001 |