Fig. 6From: Aerobic exercise and metformin on intermuscular adipose tissue (IMAT): insights from multimodal MRI and histological changes in prediabetic ratsCharacterization of lipid and glucose metabolism in intermuscular adipose tissues (IMATs). Representative western blots (A, C, E, G, I) and quantification of the gene-expression levels of peroxisome proliferators-activated receptor-γ (PPAR-γ) (B), phosphorylated PPAR-γ (p-PPAR-γ; Ser112) (F), nuclear respiratory factor-1 (NRF-1) (J), glucose transporter-4 (GLUT-4) (D), glucose transporter-1 (GLUT-1) (H), and perilipin-5 (Plin-5) (K). The data represent the mean ± the standard error of the mean (n = 5–6/group). CON control, EMA combined therapies + compound-c, EMC combined therapies, EXE moderate exercise, GAPDH glyceraldehyde-3-phosphate dehydrogenase, MET metformin, PRE prediabetes. ap < 0.05 vs. CON group; bp < 0.05 vs. PRE group. cp < 0.05 vs. MET group; dp < 0.05 vs. EXE group; ep < 0.05 vs. EMA group; fp < 0.05 vs. EMC groupBack to article page