Skip to main content

Table 1 Demographic and clinical characteristics of the study subjects

From: Quantitative profiling and diagnostic potential of one-carbon and central metabolism pools in MODY2 and T1DM

Parameters

MODY2 (n = 33)

T1DM (n = 34)

Control (n = 30)

P

Gender (M/F)

12/21

14/20

14/16

0.7088

Age (Year)

24.5 ± 15.83

19.1 ± 9.94

19.6 ± 11.18

0.2099

Birth weight (kg)

3.1 ± 0.45

3.5 ± 0.60

3.4 ± 0.49

0.074

Height (cm)

151.5 ± 21.13

160.1 ± 15.03

153.6 ± 11.98

0.094

Weight (kg)

46.4 ± 19.82

49.9 ± 17.38

46.9 ± 12.35

0.669

BMI (kg/m2)

19.1 ± 4.44

19.0 ± 4.97

19.6 ± 3.11

0.8635

Systolic blood pressure (mmHg)

105.3 ± 12.93

113 ± 15.95

108 ± 6.36

0.142

Diastolic blood pressure (mmHg)

66.2 ± 10.29

72.5 ± 11.05

71 ± 7.21

0.086

Fasting glucose (mmol/L)

6.8 ± 0.57

8.8 ± 3.48 *

4.8 ± 0.37 #

< 0.0001

Fasting insulin (mIU/L)

6.5 ± 3.48

26.5 ± 42.00 *

8.0 ± 3.82 #

0.0034

Fasting C-peptide(ng/ml)

1.03 ± 0.45

0.40 ± 0.32 *

1.12 ± 0.42

< 0.0001

HbA1c (%)

6.3 ± 0.37

8.7 ± 2.29 *

4.7 ± 0.4 #

< 0.0001

GA (%)

18.0 ± 1.46

23.5 ± 6.39 *

13.6 ± 1.19 #

< 0.0001

Triglyceride (mmol/L)

0.6 ± 0.30

0.7 ± 0.43

0.8 ± 0.50

0.080

Total cholesterol (mmol/L)

4.4 ± 0.77

4.5 ± 0.86

4.0 ± 0.67

0.087

LDL-C (mmol/L)

2.1 ± 0.57

2.6 ± 0.76 *

2.2 ± 0.68

0.016

HDL-C (mmol/L)

1.6 ± 0.26

1.3 ± 0.23 *

1.5 ± 0.21

0.0002

Creatinine (umol/L)

55.9 ± 18.10

52.6 ± 16.64

53.6 ± 11.32

0.704

Uric acid (umol/L)

258.7 ± 73.32

255.6 ± 64.20

307.5 ± 93.07

0.032

High-sensitivity C-reactive protein (mg/L)

0.3 ± 0.27

1.46 ± 2.38 *

0.7 ± 1.30

0.0179

  1. The data were expressed as mean ± standard deviation after one-way ANOVA;
  2. Non-normally distributed data were expressed as the median (25th-75th)
  3. P < 0.05 indicates a significant difference, which is indicated in bold. Differences between MODY2 and T1DM are indicated by *, and differences between MODY2 and control are indicated by #