Parameters | MODY2 (n = 33) | T1DM (n = 34) | Control (n = 30) | P |
---|---|---|---|---|
Gender (M/F) | 12/21 | 14/20 | 14/16 | 0.7088 |
Age (Year) | 24.5 ± 15.83 | 19.1 ± 9.94 | 19.6 ± 11.18 | 0.2099 |
Birth weight (kg) | 3.1 ± 0.45 | 3.5 ± 0.60 | 3.4 ± 0.49 | 0.074 |
Height (cm) | 151.5 ± 21.13 | 160.1 ± 15.03 | 153.6 ± 11.98 | 0.094 |
Weight (kg) | 46.4 ± 19.82 | 49.9 ± 17.38 | 46.9 ± 12.35 | 0.669 |
BMI (kg/m2) | 19.1 ± 4.44 | 19.0 ± 4.97 | 19.6 ± 3.11 | 0.8635 |
Systolic blood pressure (mmHg) | 105.3 ± 12.93 | 113 ± 15.95 | 108 ± 6.36 | 0.142 |
Diastolic blood pressure (mmHg) | 66.2 ± 10.29 | 72.5 ± 11.05 | 71 ± 7.21 | 0.086 |
Fasting glucose (mmol/L) | 6.8 ± 0.57 | 8.8 ± 3.48 * | 4.8 ± 0.37 # | < 0.0001 |
Fasting insulin (mIU/L) | 6.5 ± 3.48 | 26.5 ± 42.00 * | 8.0 ± 3.82 # | 0.0034 |
Fasting C-peptide(ng/ml) | 1.03 ± 0.45 | 0.40 ± 0.32 * | 1.12 ± 0.42 | < 0.0001 |
HbA1c (%) | 6.3 ± 0.37 | 8.7 ± 2.29 * | 4.7 ± 0.4 # | < 0.0001 |
GA (%) | 18.0 ± 1.46 | 23.5 ± 6.39 * | 13.6 ± 1.19 # | < 0.0001 |
Triglyceride (mmol/L) | 0.6 ± 0.30 | 0.7 ± 0.43 | 0.8 ± 0.50 | 0.080 |
Total cholesterol (mmol/L) | 4.4 ± 0.77 | 4.5 ± 0.86 | 4.0 ± 0.67 | 0.087 |
LDL-C (mmol/L) | 2.1 ± 0.57 | 2.6 ± 0.76 * | 2.2 ± 0.68 | 0.016 |
HDL-C (mmol/L) | 1.6 ± 0.26 | 1.3 ± 0.23 * | 1.5 ± 0.21 | 0.0002 |
Creatinine (umol/L) | 55.9 ± 18.10 | 52.6 ± 16.64 | 53.6 ± 11.32 | 0.704 |
Uric acid (umol/L) | 258.7 ± 73.32 | 255.6 ± 64.20 | 307.5 ± 93.07 | 0.032 |
High-sensitivity C-reactive protein (mg/L) | 0.3 ± 0.27 | 1.46 ± 2.38 * | 0.7 ± 1.30 | 0.0179 |