Inpatient screening for albuminuria and retinopathy to predict long-term mortality in type 2 diabetic patients: a retrospective cohort study

Table 2 Results of Cox regression analysis for the effects of albuminuria and retinopathy on (A) all-cause and (B) cardiovascular mortality

	Crude			Crude			Crude			Crude
	HR	95% CI	P	HR	95% CI	P	HR	95% CI	P	HR	95% CI	P
(A) All-cause-mortality
Albuminuria(−)/Retinopathy(−)	1			1						1
Albuminuria(−)/Retinopathy(+)	1.575	(1.230, 2.018)	<0.001	1.402	(1.092, 1.801)	0.008	1.529	(1.142, 2.047)	0.004	1.524	(1.138, 2.041)	0.005
Albuminuria(+)/Retinopathy(−)	2.714	(1.969, 3.741)	<0.001	2.465	(1.784, 3.405)	<0.001	2.550	(1.772, 3.671)	<0.001	2.551	(1.771, 3.676)	<0.001
Albuminuria(+)/Retinopathy(+)	2.241	(1.739, 2.887)	<0.001	2.215	(1.718, 2.856)	<0.001	2.213	(1.626, 3.014)	<0.001	2.200	(1.613, 3.001)	<0.001
(B) Cardiovascular mortality
Albuminuria(−)/Retinopathy(−)	1			1			1			1
Albuminuria(−)/Retinopathy(+)	2.519	(1.731, 3.664)	<0.001	2.155	(1.478, 3.144)	<0.001	2.412	(1.550, 3.752)	<0.001	2.434	(1.562, 3.794)	<0.001
Albuminuria(+)/Retinopathy(−)	3.264	(1.955, 5.448)	<0.001	2.858	(1.707, 4.785)	<0.001	2.866	(1.610, 5.105)	<0.001	2.762	(1.551, 4.917)	<0.001
Albuminuria(+)/Retinopathy(+)	3.489	(2.376, 5.123)	<0.001	3.440	(2.340, 5.057)	<0.001	3.339	(2.094, 5.326)	<0.001	3.327	(2.080, 5.321)	<0.001

Statistical significance (P < 0.05) is indicated in italics
HR hazard ratio, CI confidence interval
Model 1: adjusted for age and gender
Model 2: adjusted for age, gender, body mass index, systolic blood pressure, current smoker, diabetes duration, glycated hemoglobin, chronic kidney disease [estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m²], total cholesterol and triglycerides
Model 3: adjusted for age, gender, body mass index, systolic blood pressure, current smoker, diabetes duration, glycated hemoglobin, chronic kidney disease (eGFR <60 mL/min/1.73 m²), total cholesterol, triglycerides, insulin treatment and angiotensin-converting enzyme inhibitor/angiotensin II receptor blocker treatment

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