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Table 1 List of entities identified by GO and the pathways identified by KEGG of significantly up-regulated and down-regulated genes in adipose tissues of 6- and 25-week-old CP rats

From: Expression of proteins associated with adipocyte lipolysis was significantly changed in the adipose tissues of the obese spontaneously hypertensive/NDmcr-cp rat

GO accession

GO term

P value

  

6-week-old

25-week-old

  

WKY-CP

Lean-CP

WKY-CP

Lean-CP

Up-regulation

     

 GO:0016740

Transferase

1.4E-14

2.0E-08

6.8E-06

4.4E-06

 GO:0006118

Electron transport

8.0E-08

4.1E-03

3.6E-03

1.7E-04

 GO:0005489

Electron transporter activity

2.6E-07

1.0E-02

3.7E-03

1.6E-04

Down-regulation

     

 GO:0016740

Transferase

5.43E-02

3.49E-03

2.68E-04

1.41E-11

 GO:0005489

Electron transporter activity

1.09E-01

1.26E-03

1.71E-02

1.80E-05

 GO:0006118

Electron transport

1.11E-01

1.30E-03

1.73E-02

1.87E-05

Predicted pathway

     

 Up-regulation

     

  PPAR signaling pathway

4.25E-11

2.71E-03

9.73E-03

5.54E-02

  Carbon fixation

4.50E-07

1.10E-05

2.33E-03

3.11E-02

  Pentose phosphate pathway

2.84E-05

1.45E-03

3.92E-05

1.90E-01

  Glutathione metabolism

2.14E-04

4.55E-03

1.95E-04

2.21E-04

  Alkaloid biosynthesis I

9.47E-03

1.00E + 00

2.62E-03

2.79E-03

 Down-regulation

     

  ECM-receptor interaction

7.40E-04

1.64E-02

1.09E-02

3.85E-03

  Glycolysis _ Gluconeogenesis

1.59E-03

4.60E-04

5.56E-02

1.42E-01

  Fructose and mannose metabolism

3.09E-03

1.12E-03

3.01E-02

3.80E-01

  Cell Communication

9.95E-03

2.64E-03

4.71E-02

5.18E-02

  Carbon fixation

8.65E-02

4.63E-04

1.27E-03

4.82E-04

  1. WKY; Wistar Kyoto rats, Lean; spontaneously hypertensive rats (SHR/lean), CP; SHR/NDmcr-cp (cp/cp) rats.