Table 1 Clinical, anthropometric, and biochemical parameters in the NAFLD and control groups (mean ± SD)
NAFLD (n = 100) | Control (n = 45) | P | |
|---|---|---|---|
Age (years) | 47.8 ± 8.7 | 45.2 ± 7.4 | >0.05 |
Female/Male | 46/54 | 22/23 | >0.05 |
Family history of cardiovascular disease (%) | 17.2 (n = 17) | 11.1 (n = 5) | >0.05 |
Family history of diabetes (%) | 26.8 (n = 26) | 13.3 (n = 6) | >0.05 |
Cigarette smoking (%) | 29 (n = 29) | 44.4 (n = 20) | >0.05 |
BMI (kg m -2 ) | 30 ± 3.9 | 25.5 ± 2.5 | 0.000 |
Waist circumference (cm) | 95.9 ± 9.2 | 82.6 ± 5.9 | 0.000 |
Systolic pressure (mmHg) | 117.1 ± 15.0 | 110.3 ± 9.5 | 0.001 |
Diastolic pressure (mmHg) | 73.9 ± 9.5 | 69.4 ± 8.3 | 0.006 |
Fasting glucose (74–106 mg dL -1 ) | 90.9 ± 13.6 | 84.7 ± 8.1 | 0.006 |
Fasting insulin level (4–16 mIU /mL) | 15 ± 10.3 | 4.2 ± 2 | 0.002 |
HOMA-IR | 3.6 ± 3.1 | 0.95 ± 0.36 | 0.000 |
Total cholesterol (<200 mg dL -1 ) | 200.8 ± 46.6 | 171.8 ± 28.1 | 0.000 |
HDL cholesterol (40–60 mg dL -1 ) | 45.4 ± 10.8 | 51.9 ± 11.3 | 0.001 |
Triglycerides (<150 mg dL -1 ) | 167.6 ± 103.7 | 95.3 ± 34.2 | 0.000 |
Aspartate aminotransferase (<31 IU mL -1 ) | 38.7 ± 25.2 | 19.3 ± 4.8 | 0.000 |
Alanine aminotransferase (<31 IU mL -1 ) | 57.5 ± 42.6 | 18 ± 7.8 | 0.000 |
ADMA ( μmol L -1 ) | 0.8 ± 0.07 | 0.74 ± 0.2 | >0.05 |