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Table 1 Characteristics of the subjects for DPP4 %Meth analysis in VAT and WBCs

From: Comparison of the dipeptidyl peptidase-4 gene methylation levels between severely obese subjects with and without the metabolic syndrome

 

VAT experiment

WBCs experiment

Phenotypes

MetS−

MetS+

MetS−

MetS+

Number of men/women (n)

12/60

14/19

0/9

0/8

Number of MetS criteria (n)

1-2

4-5

1-2

5

Smokers (n)

13 (18.1%)

5 (16.1%)

0

0

Age (years)

35.3±8.8

35.4±7.5

35.6±8.4

36.1±8.5

BMI (kg/m2)

49.7±8.4

53.6±13.2

47.6±5.6

47.4±5.4

Waist circumference (cm)

131.3±18.7

145.0±22.0

132.3±10.5

125.6±10.3

Fasting glucose (mmol/L)

4.87±0.36**

6.23±0.71**

4.90±0.38**

6.05±0.43**

Triglycerides (mmol/L)

1.12±0.32**

2.73±1.50**

1.19±0.34**

3.19±2.14**

HDL-cholesterol (mmol/L)

1.50±0.27**

1.02±0.16**

1.48±0.30**

0.99±0.19**

LDL-cholesterol (mmol/L)

2.80±0.77

3.03±0.90

2.70±0.64

2.74±1.06

Total-cholesterol (mmol/L)

4.81±0.84

5.17±0.89

4.72±0.72

4.93±1.03

SBP (mmHg)

127.3±13.2**

149.5±15.6**

138.8±17.0

145.4±9.0

DBP (mmHg)

76.9±6.0**

93.1±9.6**

78.9±5.8**

95.9±6.7**

  1. Mean±SD or n are presented in the table.
  2. All the study subjects were non-diabetic and were not using any medication to treat MetS components.
  3. Non-normally distributed phenotypes were transformed for the comparison of mean phenotype levels between MetS groups; for the VAT experiment: body mass index (BMI) (−1/(X)), fasting glucose (−1/(X)), triglycerides (−1/(1+X)) and DBP (−1/(X)); for the WBCs experiment: triglycerides (log10X) and HDL-cholesterol (log10X). **P < 0.01.
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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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