Table 2 Cox proportional hazard model of baseline risk factors for development of microalbuminuria in 122 patients with type 1 diabetes who were followed for seven years
From: Progression to microalbuminuria in patients with type 1 diabetes: a seven-year prospective study
Baseline Data | Univariate Analysis Hazard Ratio (95% CI) p value | Multivariate Model Hazard ratio (95% CI) p value | ||
|---|---|---|---|---|
Age | 1.03 (1.00-1.06) | 0.026 | ||
Age at diagnosis | 1.03 (0.99-1.06) | 0.123 | ||
Gender | 0.92 (0.52-1.63) | 0.779 | ||
Duration of diabetes | 1.03 (0.98-1.07) | 0.247 | ||
Insulin dose | 1.34 (0.77-2.32) | 0.302 | ||
AER | 1.01 (0.96-1.07) | 0.660 | ||
Systolic blood pressure | 1.02 (0.99-1.04) | 0.170 | ||
Diastolic blood pressure | 1.02 (0.99-1.06) | 0.210 | ||
A1c | 1.02 (0.87-1.20) | 0.810 | ||
Two-hour post-prandial glycemia | 0.99 (0.99-1.00) | 0.294 | ||
Fasting glycemia | 1.00(0.99-1.01) | 0.234 | ||
BMI | 1.12 (1.03-1.22) | 0.006 | 1.12 (1.03-1.21) | 0.01 |
Total cholesterol level | 1.01 (1.0-1.01) | 0.042 | ||
HDL cholesterol level | 0.99 (0.98-1.02) | 0.930 | ||
Triglyceride level | 1.00 (0.99-1.01) | 0.08 | ||
LDL cholesterol level | 1.01 (1.00-1.01) | 0.045 | ||
Cholesterol/HDL ratio | 1.32 (1.07-1.63) | 0.010 | 1.32 (1.05-1.67) | 0.019 |
LDL/HDL ratio | 1.26 (0.97-1.62) | 0.079 | ||
Presence of retinopathy | 1.37 (0.33-5.68) | 0.667 | ||
Family history of type 2 diabetes | 2.03 (1.06-3.92) | 0.044 | ||