Improvement of renal oxidative stress markers after ozone administration in diabetic nephropathy in rats

Table 1 Effect of six weeks ozone treatment on different parameters in STZ induced diabetes in rats.

Group	SBP (mmHg)	DBP (mmHg)	(Hb A_1c%)	BUN (mmol/L)	Creatinine (μmol/L)
C	106.1 ± 5.9	88.3 ± 5.6	7.4 ± 1.36	5.72 ± 0.25	45.9 ± 2.6
O	101 ± 4.8	79.5 ± 2.1	7.1 ± 1.25	4.26 ± 0.82	36.2 ± 4.4
D	165.4 ± 6.7 * °	127.3 ± 4.2 * °	16.1 ± 1.47 * °	35.15 ± 4.35 * °	184.7 ± 1.8 * °
DI	109.5 ± 3.6 ° #	100.2 ± 4.1 ° #	8.3 ± 0.38 ° #	27.50 ± 5.79 * °	165.3 ± 11.4 * °
DO	102.5 ± 5.2 ° #	97.3 ± 5.3 ° #	8.9 ± 1.02 ° #	11.35 ± 5.37 * ° # ˆ	92.8 ± 15.1 * ° #
DOI	87.8 ± 6.5 # ˆ ¥	78.9 ± 3.2 # ˆ ¥	7.3 ± 0.24 # ˆ ¥	5.81 ± 0.73 # ˆ ¥	47.7 ± 0.88 # ˆ ¥

Effect of treatment with ozone on systolic (SBP), diastolic blood pressures (CBP), glycosylated Hb (Hb A_1c), serum creatinine and blood urea nitrogen (BUN) (Means ± SE) in control and experimental groups of rats (n = 10).
* Significant change from the corresponding values in Non-diabetes control group.
° Significant change from the corresponding values in Non-diabetes ozone-control group.
# Significant change from the corresponding values in diabetes control group.
ˆ Significant change from the corresponding values in diabetes insulin treated group.
¥ Significant change from the corresponding values in diabetes ozone treated group.

ISSN: 1758-5996