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  1. FOXC2 has lately been implicated in diabetes and obesity as well as mitochondrial function and biogenesis and also as a regulator of mtTFA/Tfam. In this study, the expression of FOXC2 and selected genes involv...

    Authors: Joakim Håkansson, Björn Eliasson, Ulf Smith and Sven Enerbäck

    Citation: Diabetology & Metabolic Syndrome 2011 3:32

    Content type: Research

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  2. There are an increasing number of patients suffering from fatty liver caused by type 2 diabetes. We intended to study the preventive and therapeutic effect of L-carnitine (LC) on nonalcoholic fatty liver disea...

    Authors: Yunqiu Xia, Qing Li, Weizhen Zhong, Jing Dong, Zhulin Wang and Chunbo Wang

    Citation: Diabetology & Metabolic Syndrome 2011 3:31

    Content type: Research

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  3. Prevalence of men with cardiometabolic risk factors (CMRF) is increasing in Japan. Few studies have comprehensively examined the relation between lifestyles and CMRF.

    Authors: Sayuri Katano, Yasuyuki Nakamura, Nagako Okuda, Yoshitaka Murakami, Nagako Chiba, Katsushi Yoshita, Taichiro Tanaka, Junko Tamaki, Toru Takebayashi, Akira Okayama, Katsuyuki Miura, Tomonori Okamura and Hirotsugu Ueshima

    Citation: Diabetology & Metabolic Syndrome 2011 3:30

    Content type: Research

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  4. Higher serological prevalence rates of helicobacter pylori (H. pylori) infection have been reported in patients with type 1 diabetes (T1DM) and autoimmune thyroiditis (AT). Patients with T1DM are at increased ...

    Authors: Mervat M El-Eshmawy, Amany K El-Hawary, Soma S Abdel Gawad and Azza A El-Baiomy

    Citation: Diabetology & Metabolic Syndrome 2011 3:28

    Content type: Research

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  5. MicroRNAs (miRNAs) are a newly discovered type of small non-protein coding RNA that function in the inhibition of effective mRNA translation, and may serve as susceptibility genes for various disease developme...

    Authors: Xiaofan Mi, Hongzhi He, Yangxin Deng, Abert M Levin, Jin-Xiong She, Qing-Sheng Mi and Li Zhou

    Citation: Diabetology & Metabolic Syndrome 2011 3:27

    Content type: Letter to the Editor

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  6. Comorbid depression in diabetes has been suggested as one of the possible causes of an inadequate glycemic control. The purpose of this study was to investigate the association between major depression and the...

    Authors: Marcelo Papelbaum, Rodrigo O Moreira, Walmir Coutinho, Rosane Kupfer, Leão Zagury, Silvia Freitas and José C Appolinário

    Citation: Diabetology & Metabolic Syndrome 2011 3:26

    Content type: Research

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  7. C-reactive protein (CRP) is positively associated with risk for cardiovascular disease and all-cause mortality. Some but not all randomized and non-randomized clinical trials found significant associations bet...

    Authors: Jiatao Ye, James N Kiage, Donna K Arnett, Alfred A Bartolucci and Edmond K Kabagambe

    Citation: Diabetology & Metabolic Syndrome 2011 3:24

    Content type: Research

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  8. Although it is well known in the literature that high triglyceride serum (TG) levels can jeopardize the metabolic control, little is known about the influence of low TG on type 1 diabetes patients (T1D). The a...

    Authors: Leticia M Alcantara, Nathalia E Silveira, Joana R Dantas, Paula B Araujo, Marcus M de Oliveira, Adolpho Milech, Lenita Zajdenverg, Melanie Rodacki and José EP de Oliveira

    Citation: Diabetology & Metabolic Syndrome 2011 3:22

    Content type: Short report

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  9. The presence of microalbuminuria can be associated with overt nephropathy and cardiovascular disease in patients with type 1 diabetes (T1D). We aimed to determine the incidence and evaluate the baseline predic...

    Authors: Roberta A Cobas, Bráulio Santos, Pedro CB da Silva, Ricardo Neves and Marilia B Gomes

    Citation: Diabetology & Metabolic Syndrome 2011 3:21

    Content type: Research

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  10. The purpose of this study was to evaluate the effects of cigarette smoke exposure before pregnancy on diabetic rats and their offspring development.

    Authors: Débora C Damasceno, Yuri K Sinzato, Paula H Lima, Maricelma S de Souza, Kleber E Campos, Bruna Dallaqua, Iracema M Calderon, Marilza V Rudge and Gustavo T Volpato

    Citation: Diabetology & Metabolic Syndrome 2011 3:20

    Content type: Research

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  11. To investigate and compare the incidence of histopathological placental lesions in mild gestational hyperglycemia, gestational diabetes and overt diabetes at term and preterm gestation.

    Authors: Marilza VC Rudge, César P Lima, Débora C Damasceno, Yuri K Sinzato, Gustavo Napoli, Cibele VC Rudge, Franciane Q Gallego and Iracema MP Calderon

    Citation: Diabetology & Metabolic Syndrome 2011 3:19

    Content type: Research

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  12. Although the positive relationship between insulin resistance (IR) and central obesity is well known, the direct relationship between waist circumference and IR is not clear yet and there is no consensus regar...

    Authors: Azita Zadeh-Vakili, Fahimeh Ramezani Tehrani and Farhad Hosseinpanah

    Citation: Diabetology & Metabolic Syndrome 2011 3:18

    Content type: Research

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  13. Adipokines, e.g. TNFα, IL-6 and leptin increase insulin resistance, and consequent hyperinsulinaemia influences breast cancer progression. Beside its mitogenic effects, insulin may influence adipokine producti...

    Authors: Jean Grisouard, Kaethi Dembinski, Doris Mayer, Ulrich Keller, Beat Müller and Mirjam Christ-Crain

    Citation: Diabetology & Metabolic Syndrome 2011 3:16

    Content type: Short report

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  14. A large prospective study in patients with type 2 diabetes (T2D), the German D2C cohort, is presently being enumerated to investigate risk factors of incident cancer in diabetic patients.

    Authors: Hans-Werner Hense, Hiltraud Kajüter, Jürgen Wellmann and Wolf U Batzler

    Citation: Diabetology & Metabolic Syndrome 2011 3:15

    Content type: Research

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  15. Insulin analogues are increasingly considered as an alternative to human insulin in the therapy of diabetes mellitus. Insulin analogues (IAs) are chemically different from human insulin and may have different ...

    Authors: Harald G Enzmann and Martina Weise

    Citation: Diabetology & Metabolic Syndrome 2011 3:14

    Content type: Review

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  16. In order to provide comprehensive information on the differences in bioactivity between human insulin and insulin analogues, published in vitro comparisons of human insulin and the rapid acting analogues insulin ...

    Authors: Haim Werner and Ernst A Chantelau

    Citation: Diabetology & Metabolic Syndrome 2011 3:13

    Content type: Review

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  17. There is a well established link between obesity and cancer. Emerging research is characterising this relationship further and delineating the specific role of excess visceral adiposity, as opposed to simple o...

    Authors: Claire L Donohoe, Suzanne L Doyle and John V Reynolds

    Citation: Diabetology & Metabolic Syndrome 2011 3:12

    Content type: Review

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  18. Either endogenous or exogenous hyperinsulinemia in the setting of insulin resistance promotes phosphorylation and activation of farnesyltransferase, a ubiquitous enzyme that farnesylates Ras protein. Increased...

    Authors: Boris Draznin

    Citation: Diabetology & Metabolic Syndrome 2011 3:10

    Content type: Review

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  19. The concordance of microalbuminuria and diabetic retinopathy (DR) has been well reported in persons with type 1 diabetes; however, for type 2 diabetes, there is paucity of data especially from population-based...

    Authors: Padmaja K Rani, Rajiv Raman, Aditi Gupta, Swakshyar S Pal, Vaitheeswaran Kulothungan and Tarun Sharma

    Citation: Diabetology & Metabolic Syndrome 2011 3:9

    Content type: Research

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  20. Bus and truck drivers are apparently more involved in metabolic syndrome and its complications due to their working conditions. The related impacts are not only harmful for driver's health, but also may endang...

    Authors: Hamid R Saberi, Ali R Moravveji, Esmaeil Fakharian, Masoud Motalebi kashani and Ali R Dehdashti

    Citation: Diabetology & Metabolic Syndrome 2011 3:8

    Content type: Research

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  21. Coronary artery disease (CAD) is among the main causes of death in developed countries, and diet and lifestyle can influence CAD incidence.

    Authors: Mauro Massao Takahashi, Erick Prado de Oliveira, Ana Lygia Rochitti de Carvalho, Lidiane Affonso de Souza Dantas, Franz Homero Paganini Burini, Kátia Cristina Portero-McLellan and Roberto Carlos Burini

    Citation: Diabetology & Metabolic Syndrome 2011 3:7

    Content type: Research

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  22. Nonalcoholic fatty liver disease (NAFLD) is the most frequent disease associated with abnormal liver tests that is characterized by a wide spectrum of liver damage, ranging from simple macro vesicular steatosi...

    Authors: Fernanda BU Pulzi, Raul Cisternas, Murilo R Melo, Cristiane MF Ribeiro, Carlos A Malheiros and João E Salles

    Citation: Diabetology & Metabolic Syndrome 2011 3:3

    Content type: Research

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  23. This paper reviews the incidence, pathogenetic mechanisms and management strategies of diabetes mellitus in patients with human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS). It cl...

    Authors: Sanjay Kalra, Bharti Kalra, Navneet Agrawal and AG Unnikrishnan

    Citation: Diabetology & Metabolic Syndrome 2011 3:2

    Content type: Review

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  24. While several studies have identified the anaerobic threshold (AT) through the responses of blood lactate, ventilation and blood glucose others have suggested the response of the heart rate variability (HRV) a...

    Authors: Marcelo M Sales, Carmen Sílvia G Campbell, Pâmella K Morais, Carlos Ernesto, Lúcio F Soares-Caldeira, Paulo Russo, Daisy F Motta, Sérgio R Moreira, Fábio Y Nakamura and Herbert G Simões

    Citation: Diabetology & Metabolic Syndrome 2011 3:1

    Content type: Research

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  25. Anxiety and depression contribute to poor disease outcomes among individuals with diabetes. This study aimed to assess the prevalence of anxiety and depression and to identify their associated factors includin...

    Authors: Ali Khan Khuwaja, Saima Lalani, Raheem Dhanani, Iqbal Syed Azam, Ghazala Rafique and Franklin White

    Citation: Diabetology & Metabolic Syndrome 2010 2:72

    Content type: Research

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  26. To date, there have been no reports on the prevalence of adrenal masses in type 2 diabetic patients. The present study aimed to evaluate the prevalence of adrenal incidentaloma in type 2 diabetic patients in J...

    Authors: Naoki Hiroi, Mariko Sue, Aya Yoshihara, Takamasa Ichijo, Mayumi Yoshida-Hiroi, Mariko Higa and Gen Yoshino

    Citation: Diabetology & Metabolic Syndrome 2010 2:71

    Content type: Research

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  27. Many trace elements, among which metals, are indispensable for proper functioning of a myriad of biochemical reactions, more particularly as enzyme cofactors. This is particularly true for the vast set of proc...

    Authors: Nicolas Wiernsperger and JeanRobert Rapin

    Citation: Diabetology & Metabolic Syndrome 2010 2:70

    Content type: Review

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  28. Saxagliptin is a potent, selective DPP4 inhibitor. Highlights from abstracts presented at the 2010 meetings of the European Association for the Study of Diabetes and the American Diabetes Association include s...

    Authors: Pablo J Aschner

    Citation: Diabetology & Metabolic Syndrome 2010 2:69

    Content type: Review

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  29. While the International Diabetes Federation (IDF) has ethnic specific waist circumference (WC) cut-points for the metabolic syndrome for Asian populations it is not known whether the cut-points for black popul...

    Authors: Marshall K Tulloch-Reid, Trevor S Ferguson, Novie OM Younger, Jan Van den Broeck, Michael S Boyne, Jennifer M Knight-Madden, Maureen E Samms-Vaughan, Deana E Ashley and Rainford J Wilks

    Citation: Diabetology & Metabolic Syndrome 2010 2:68

    Content type: Research

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  30. The Metabolic syndrome (MS) consists of central obesity, glucose intolerance, hyperinsulinemia, low high density lipoproteins, high triglycerides and hypertension. Different studies have observed that MS cause...

    Authors: Rajiv Raman, Aditi Gupta, Swakshyar S Pal, Suganeswari Ganesan, Kadri Venkatesh, Vaitheeswaran Kulothungan and Tarun Sharma

    Citation: Diabetology & Metabolic Syndrome 2010 2:67

    Content type: Research

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  31. Oral insulin is an exciting area of research and development in the field of diabetology. This brief review covers the various approaches used in the development of oral insulin, and highlights some of the rec...

    Authors: Sanjay Kalra, Bharti Kalra and Navneet Agrawal

    Citation: Diabetology & Metabolic Syndrome 2010 2:66

    Content type: Review

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  32. Despite ongoing findings on the relationship between elevated levels of alanine and aspartate aminotransferases (ALT and AST) and metabolic syndrome (MetS), this association in diabetic patients without a know...

    Authors: Alireza Esteghamati, Arsia Jamali, Omid Khalilzadeh, Sina Noshad, Mohammad Khalili, Ali Zandieh, Afsaneh Morteza and Manouchehr Nakhjavani

    Citation: Diabetology & Metabolic Syndrome 2010 2:65

    Content type: Research

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  33. Conjugated linoleic acid (CLA) is a class of 28 positional and geometric isomers of linoleic acid octadecadienoic.Currently, it has been described many benefits related to the supplementation of CLA in animals...

    Authors: Daniela C Gonçalves, Fabio S Lira, Luiz C Carnevali Jr, Jose C Rosa, Gustavo D Pimentel and Marília Seelaender

    Citation: Diabetology & Metabolic Syndrome 2010 2:62

    Content type: Letter to the Editor

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  34. The increased intake of dietary fructose can be associated with alterations on energy homeostasis and lipid/carbohydrate metabolism, such as insulin resistance and dislipidemia. On the other hand, the ingestio...

    Authors: Caio SM Motoyama, Mônica JS Pinto, Fabio S Lira, Eliane B Ribeiro, Claudia MO do Nascimento and Lila M Oyama

    Citation: Diabetology & Metabolic Syndrome 2010 2:61

    Content type: Research

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  35. The diagnosis of Sudeck's syndrome stage 1 (nowadays termed complex regional pain syndrome I, abbreviated CRPS I) is based on clinical features, namely swelling and pain in a limb. Plain X-ray may be normal. I...

    Authors: Ludger W Poll, Philipp Weber, Hermann-Josef Böhm, Nahid Ghassem-Zadeh and Ernst A Chantelau

    Citation: Diabetology & Metabolic Syndrome 2010 2:60

    Content type: Case report

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  36. There is a remarkable increase in cardiovascular disease after menopause. On the other hand, metabolic syndrome as a collection of risk factors has a known effect on cardiovascular diseases. Hormone changes ar...

    Authors: Ramin Heidari, Masoumeh Sadeghi, Mohammad Talaei, Katayoun Rabiei, Noushin Mohammadifard and Nizal Sarrafzadegan

    Citation: Diabetology & Metabolic Syndrome 2010 2:59

    Content type: Research

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