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  1. Recent in vitro and in vivo studies have suggested a critical role of osteocalcin (OC), especially the undercarboxylated form (ucOC), in insulin secretion and insulin sensitivity. The objective of this study was ...

    Authors: Katsuhito Mori, Masanori Emoto, Koka Motoyama, Eiko Lee, Shinsuke Yamada, Tomoaki Morioka, Yasuo Imanishi, Tetsuo Shoji and Masaaki Inaba

    Citation: Diabetology & Metabolic Syndrome 2012 4:53

    Content type: Short report

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  2. Functional TRIB3 Q84R polymorphism has been associated with insulin resistance. Obestatin, improving insulin resistance, exerts obscure effects on metabolic syndrome (MetS) and carotid atherosclerosis. Aims to in...

    Authors: Ai-dong Cui, Ning-ning Gai, Xiu-hua Zhang, Ke-zhi Jia, Yan-li Yang and Ze-jun Song

    Citation: Diabetology & Metabolic Syndrome 2012 4:52

    Content type: Research

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  3. Abnormal circadian blood pressure patterns have been associated with cardiovascular disease in diabetes mellitus. We have described that the acrophase of diastolic blood pressure (DBP) registered in type 1 dia...

    Authors: Elena Matteucci, Luca Della Bartola and Ottavio Giampietro

    Citation: Diabetology & Metabolic Syndrome 2012 4:51

    Content type: Short report

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  4. Cytokines secreted by the adipose tissue influence inflammation and insulin sensitivity, and lead to metabolic disturbances. How certain single-nucleotide polymorphisms (SNPs) interfere on lifestyle interventi...

    Authors: Maira LR Curti, Milena M Pires, Camila R Barros, Antonela Siqueira-Catania, Marcelo Macedo Rogero and Sandra RG Ferreira

    Citation: Diabetology & Metabolic Syndrome 2012 4:49

    Content type: Research

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  5. To evaluate the impact of type 1 diabetes (T1D) on family functioning and child-rearing practices from parents’ point of view, to assess parents’ health-related quality of life and to explore the relations bet...

    Authors: Fani Eta Korn Malerbi, Carlos Antonio Negrato and Marilia B Gomes

    Citation: Diabetology & Metabolic Syndrome 2012 4:48

    Content type: Research

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  6. The American Diabetes Association (ADA) has published several diabetes treatment algorithms, but none have been tested in real-life settings. The aim of this study is to analyze the feasibility of achieving an...

    Authors: Luciana V Viana, Cristiane B Leitão, Maria de Fátima Grillo, Ennio P C C Rocha, Juliana K Brenner, Rogério Friedman and Jorge L Gross

    Citation: Diabetology & Metabolic Syndrome 2012 4:47

    Content type: Research

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  7. To determine whether there were differences in depressed mood between overweight/obese men with and without type 2 diabetes (T2DM) and to examine any associations between depressed mood, physical functioning, ...

    Authors: Itamar Levinger, Steve Selig, George Jerums, Andrew Stewart, Cadeyrn J Gaskin and David L Hare

    Citation: Diabetology & Metabolic Syndrome 2012 4:46

    Content type: Research

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  8. The worldwide prevalence of obesity has lead to increased efforts to find therapies to treat obesity-related pathologies. Ceramide is a well-established mediator of several health problems that arise from adip...

    Authors: Katherine A Erickson, Melissa E Smith, Tamil S Anthonymuthu, Michael J Evanson, Eric S Brassfield, Aimee E Hodson, M Andrew Bressler, Braden J Tucker, Mikayla O Thatcher, John T Prince, Chad R Hancock and Benjamin T Bikman

    Citation: Diabetology & Metabolic Syndrome 2012 4:45

    Content type: Research

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  9. To determine the characteristics of clinical care offered to type 1 diabetic patients across the four distinct regions of Brazil, with geographic and contrasting socioeconomic differences. Glycemic control, pr...

    Authors: Marília B Gomes, Roberta A Cobas, Alessandra S Matheus, Lucianne R Tannus, Carlos Antonio Negrato, Melanie Rodacki, Neuza Braga, Marilena M Cordeiro, Jorge L Luescher, Renata S Berardo, Marcia Nery, Maria do Carmo Arruda-Marques, Luiz E Calliari, Renata M Noronha, Thais D Manna, Lenita Zajdenverg…

    Citation: Diabetology & Metabolic Syndrome 2012 4:44

    Content type: Research

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  10. Two different types of adipose tissues can be found in humans enabling them to respond to starvation and cold: white adipose tissue (WAT) is generally known and stores excess energy in the form of triacylglyce...

    Authors: Bodo Haas, Paul Schlinkert, Peter Mayer and Niels Eckstein

    Citation: Diabetology & Metabolic Syndrome 2012 4:43

    Content type: Review

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  11. Obesity contributes to Type 2 diabetes by promoting systemic insulin resistance. Obesity causes features of metabolic dysfunction in the adipose tissue that may contribute to later impairments of insulin actio...

    Authors: Ann Hammarstedt, Timothy E Graham and Barbara B Kahn

    Citation: Diabetology & Metabolic Syndrome 2012 4:42

    Content type: Research

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  12. Pregnancy affects both the maternal and fetal metabolism and even in nondiabetic women exerts a diabetogenic effect. Among pregnant women, 2 to 17.8% develop gestational diabetes. Pregnancy can also occur in w...

    Authors: Carlos Antonio Negrato, Rosiane Mattar and Marilia B Gomes

    Citation: Diabetology & Metabolic Syndrome 2012 4:41

    Content type: Review

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  13. Familial partial lipodystrophies (FPLD) are clinically heterogeneous disorders characterized by selective loss of adipose tissue, insulin resistance and metabolic complications. Until genetic studies become av...

    Authors: Cynthia M Valerio, Lenita Zajdenverg, Jose Egidio P de Oliveira, Patricia B Mory, Regina Moyses and Amélio F Godoy-Matos

    Citation: Diabetology & Metabolic Syndrome 2012 4:40

    Content type: Review

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    The Erratum to this article has been published in Diabetology & Metabolic Syndrome 2015 7:19

  14. Individuals with diabetes who are smokers have higher risks of cardiovascular disease, premature death, and microvascular complications. The present study aims to determine the prevalence of symptoms of depres...

    Authors: Simone Franco Osme, LudmillaDell’IsolaPelegriniMelo Ferreira, Mariana Tanus Jorge, Juliana de Souza Andréo, MariaLuizaMendonçaPereira Jorge, Rogério de Melo Costa Pinto, Miguel Tanús Jorge and Paulo Tannús Jorge

    Citation: Diabetology & Metabolic Syndrome 2012 4:39

    Content type: Research

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  15. Metabolic Syndrome (MetS) is associated with increased risk of morbi-mortality, thus the characterization of the population magnitude of this syndrome is critical for allocating health care. However, prevalenc...

    Authors: Maria C Foss-Freitas, Patricia M Gomes, Regina CG Andrade, Roberta C Figueiredo, Ana E Pace, Amaury L Dal Fabbro, Luciana Z Monteiro, Laercio J Franco and Milton C Foss

    Citation: Diabetology & Metabolic Syndrome 2012 4:38

    Content type: Research

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  16. Omentin is an adipocytokine that is abundantly expressed in visceral fat tissue. We investigated the association of omentin with the number of metabolic risk factors.

    Authors: Rei Shibata, Noriyuki Ouchi, Ryotaro Takahashi, Yuya Terakura, Koji Ohashi, Nobuo Ikeda, Akiko Higuchi, Hiroko Terasaki, Shinji Kihara and Toyoaki Murohara

    Citation: Diabetology & Metabolic Syndrome 2012 4:37

    Content type: Short report

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  17. The aim of this study was to assess efficacy and safety of saxagliptin monotherapy for up to 76 weeks in patients with type 2 diabetes mellitus (T2DM) and inadequate glycemic control, with main efficacy assess...

    Authors: Robert Frederich, Robert McNeill, Niklas Berglind, Douglas Fleming and Roland Chen

    Citation: Diabetology & Metabolic Syndrome 2012 4:36

    Content type: Research

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  18. Environmental conditions in early life can induce permanent physiological changes, sometimes increasing the risk of chronic diseases during adulthood. Neural and peripheral circuits controlling energy balance ...

    Authors: Carolina A Aguirre, Valeska A Castillo and Miguel N Llanos

    Citation: Diabetology & Metabolic Syndrome 2012 4:35

    Content type: Research

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  19. Our study addressed potential associations between fatty liver and small, dense low-density lipoprotein cholesterol (sd-LDL-C) levels using a cross-sectional analysis.

    Authors: Kaori Hosoyamada, Hirofumi Uto, Yasushi Imamura, Yasunari Hiramine, Eriko Toyokura, Yoshihiro Hidaka, Tomomi Kuwahara, Ken Kusano, Kazuto Saito, Makoto Oketani, Akio Ido and Hirohito Tsubouchi

    Citation: Diabetology & Metabolic Syndrome 2012 4:34

    Content type: Research

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  20. This study was undergone to evaluate the in-vivo anti-hyperglycemic and antioxidant potential of ethanolic extract of leaves of Tecomella undulata Seem. on streptozotocin-nicotinamide induced type 2 diabetic rats...

    Authors: Suresh Kumar, Sunil Sharma, Neeru Vasudeva and Varun Ranga

    Citation: Diabetology & Metabolic Syndrome 2012 4:33

    Content type: Research

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  21. Frequent consumption of a diet high in fat and sucrose contributes to lifestyle-related diseases. However, limited information is available regarding the short-term effects of such a diet on the onset of obesi...

    Authors: Zhi-Hong Yang, Hiroko Miyahara, Jiro Takeo and Masashi Katayama

    Citation: Diabetology & Metabolic Syndrome 2012 4:32

    Content type: Research

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  22. Application of SMS in reminders of medical appointments and delivering medical tests is not new, however its focus on clinical interventions has just begun. Usage of tailored SMS reminders to increase adherenc...

    Authors: Talha Riaz, Haris Riaz, Syed A Hussain and Danish Kherani

    Citation: Diabetology & Metabolic Syndrome 2012 4:31

    Content type: Letter to the Editor

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  23. Diabetes mellitus type 1 is an autoimmune disorder caused by lymphocytic infiltration and beta cells destruction. Curcumin has been identified as a potent inducer of heme-oxygenase-1 (HO-1), a redoxsensitive i...

    Authors: Mohamed T Abdel Aziz, Mohamed F El-Asmar, Ibrahim N El-Ibrashy, Ameen M Rezq, Abdulrahman L Al-Malki, Mohamed A Wassef, Hanan H Fouad, Hanan H Ahmed, Fatma M Taha, Amira A Hassouna and Heba M Morsi

    Citation: Diabetology & Metabolic Syndrome 2012 4:30

    Content type: Research

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  24. Previous studies have reported that microalbuminuria is an independent risk factor for the prevalence of diabetic retinopathy (DR) in patients with type 2 diabetes mellitus (DM). For this reason, the clinical ...

    Authors: Ho Ra, Ji Han Yoo, Woo Ho Ban, Ho Cheol Song, Seong Su Lee, Sung Rae Kim, Soon Jib Yoo, Yong-Soo Kim, Euy Jin Choi and Yong Kyun Kim

    Citation: Diabetology & Metabolic Syndrome 2012 4:29

    Content type: Research

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  25. Prior studies reported conflicting findings on the association between metabolic syndrome and inflammatory biomarkers. We tested the cross-sectional associations between metabolic syndrome and nine inflammator...

    Authors: Dhayana Dallmeier, Martin G Larson, Ramachandran S Vasan, John F Keaney Jr, Joao D Fontes, James B Meigs, Caroline S Fox and Emelia J Benjamin

    Citation: Diabetology & Metabolic Syndrome 2012 4:28

    Content type: Research

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  26. The prevalence and magnitude of obesity in the children and the adolescents have increased dramatically in the developing countries over the last 20–30 years. The prevalence of metabolic syndrome (MS) in child...

    Authors: Nashwa Nabil Kamal and Merhan Mamdouh Ragy

    Citation: Diabetology & Metabolic Syndrome 2012 4:27

    Content type: Research

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  27. To evaluate the importance of oral glucose tolerance test (OGTT) in predicting diabetes and cardiovascular disease in patients with and without Metabolic Syndrome from a population treated in a primary care unit.

    Authors: Camila Furtado de Souza, Mériane Boeira Dalzochio, Francisco Jorge Arsego de Oliveira, Jorge Luiz Gross and Cristiane Bauermann Leitão

    Citation: Diabetology & Metabolic Syndrome 2012 4:25

    Content type: Research

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  28. Metabolic Syndrome (MS) increases the risk for Coronary Artery Disease, stroke and diabetes. MS is twice more common amongst South Asian immigrants in US compared to native Caucasians. There are no nationally ...

    Authors: Prasad Katulanda, Priyanga Ranasinghe, Ranil Jayawardana, Rezvi Sheriff and David R Matthews

    Citation: Diabetology & Metabolic Syndrome 2012 4:24

    Content type: Research

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  29. Reduction of dietary carbohydrates and corresponding insulin doses stabilizes and lowers mean blood glucose in individuals with type 1 diabetes within days. The long-term adherence for persons who have learned...

    Authors: Jørgen Vesti Nielsen, Caroline Gando, Eva Joensson and Carina Paulsson

    Citation: Diabetology & Metabolic Syndrome 2012 4:23

    Content type: Short report

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  30. Available definition criteria for metabolic syndrome (MS) have similarities and inconsistencies. The aim of this study was to determine the prevalence of MS in a group of Cameroonians with type 2 diabetes, acc...

    Authors: Andre P Kengne, Serge N Limen, Eugene Sobngwi, Cathérine FT Djouogo and Christophe Nouedoui

    Citation: Diabetology & Metabolic Syndrome 2012 4:22

    Content type: Research

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  31. Prevalence of diabetes mellitus (DM) has reached epidemic proportions in Sri Lanka. Presently there are studies on the community prevalence of distal peripheral neuropathy (DPN) in Sri Lanka. We describe preva...

    Authors: Prasad Katulanda, Priyanga Ranasinghe, Ranil Jayawardena, Godwin R Constantine, M H Rezvi Sheriff and David R Matthews

    Citation: Diabetology & Metabolic Syndrome 2012 4:21

    Content type: Research

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  32. The prevalence of metabolic syndrome (MetS) has increased in developing countries in recent decades. This syndrome, a clustering of metabolic abnormalities, has been correlated to various socioeconomic and beh...

    Authors: Eliane Said Dutra, Kênia MaraBaiocchi de Carvalho, Édina Miyazaki, Edgar Merchán- Hamann and Marina Kiyomi Ito

    Citation: Diabetology & Metabolic Syndrome 2012 4:20

    Content type: Research

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  33. The advanced glycation end products, namely AGEs, contribute to long-termed complications of diabetes mellitus, including macroangiopathy, where smooth muscle cells (SMC) proliferation stimulated by platelet-d...

    Authors: Maria Lúcia Corrêa-Giannella, Maria Regina Andrade de Azevedo, Derek LeRoith and Daniel Giannella-Neto

    Citation: Diabetology & Metabolic Syndrome 2012 4:19

    Content type: Research

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  34. The incidence of type 2 diabetes mellitus (T2DM) has been increasing in recent years. Sleep loss and circadian rhythm abnormalities are thought to be one of the underlying causes of adverse metabolic health. H...

    Authors: Tomoko Nakanishi-Minami, Ken Kishida, Tohru Funahashi and Iichiro Shimomura

    Citation: Diabetology & Metabolic Syndrome 2012 4:18

    Content type: Research

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  35. Asymmetric NG,NG-dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase, is regulated by the enzymatic participants of synthetic and metabolic processes, i.e., type I protein N-arginine methylt...

    Authors: Hiroaki Iwasaki

    Citation: Diabetology & Metabolic Syndrome 2012 4:17

    Content type: Short report

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  36. In recent decades, metabolic syndrome has become a public health problem throughout the world. Longitudinal studies in humans have several limitations due to the invasive nature of certain analyses and the siz...

    Authors: Ana Carolina Ghezzi, Lucieli Teresa Cambri, José Diego Botezelli, Carla Ribeiro, Rodrigo Augusto Dalia and Maria Alice Rostom de Mello

    Citation: Diabetology & Metabolic Syndrome 2012 4:16

    Content type: Research

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  37. The body’s total antioxidant capacity represents a sum of the antioxidant capacity of various tissues/organs. A decrease in the body’s antioxidant capacity may induce oxidative stress and subsequent metabolic ...

    Authors: Shi-Sheng Zhou, Da Li, Yi-Ming Zhou and Ji-Min Cao

    Citation: Diabetology & Metabolic Syndrome 2012 4:15

    Content type: Review

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  38. Elevated serum uric acid is associated with obesity, hypertension and metabolic syndrome. Because a linear relationship exists between serum and salivary uric acid (SUA) concentration, saliva testing may be a ...

    Authors: Maria Soukup, Izabela Biesiada, Aaron Henderson, Benmichael Idowu, Derek Rodeback, Lance Ridpath, Edward G Bridges, Andrea M Nazar and Kristie Grove Bridges

    Citation: Diabetology & Metabolic Syndrome 2012 4:14

    Content type: Short report

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  39. The number of people with diabetes and pre-diabetes are exponentially increasing. Studies on humans have shown the beneficial effects of Zinc supplementation in patients with diabetes. The present study aims t...

    Authors: R Jayawardena, P Ranasinghe, P Galappatthy, RLDK Malkanthi, GR Constantine and P Katulanda

    Citation: Diabetology & Metabolic Syndrome 2012 4:13

    Content type: Review

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  40. High plasma uric acid (UA) is a precipitating factor for gout and renal calculi as well as a strong risk factor for Metabolic Syndrome and cardiovascular disease. The main causes for higher plasma UA are eithe...

    Authors: Erick Prado de Oliveira and Roberto Carlos Burini

    Citation: Diabetology & Metabolic Syndrome 2012 4:12

    Content type: Review

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  41. Controversies surround a diagnosis of gestational diabetes mellitus (GDM). The objective of this study was to evaluate the oral glucose tolerance test (OGTT) for the prediction of adverse gestational and perin...

    Authors: Patricia M Rehder, Belmiro G Pereira and João Luiz Pinto e Silva

    Citation: Diabetology & Metabolic Syndrome 2012 4:10

    Content type: Research

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  42. Preclinical experiments on large animals are indispensable for evaluating the effectiveness of diabetes therapies. Miniature swine are well suited for such studies due to their physiological and pathophysiolog...

    Authors: Armin Strauss, Vasily Moskalenko, Christian Tiurbe, Irina Chodnevskaja, Stephan Timm, Verena A Wiegering, Christoph-Thomas Germer and Karin Ulrichs

    Citation: Diabetology & Metabolic Syndrome 2012 4:7

    Content type: Research

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  43. Sleep-disordered breathing (SDB), especially obstructive sleep apnea (OSA), has frequent complications include hypertension, dyslipidemia and insulin resistance based on abdominal obesity or excess visceral fa...

    Authors: Tomoko Nakanishi-Minami, Ken Kishida, Yasuhiko Nakagawa, Munetaka Nishio, Chisa Nakagawa, Yoshiharu Nishida, Koji Yanagi, Ryoko Yoshida, Tohru Funahashi and Iichiro Shimomura

    Citation: Diabetology & Metabolic Syndrome 2012 4:6

    Content type: Short report

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  44. This study aimed to examine the effects of intermittent and continuous swimming training on muscle protein metabolism in neonatal alloxan-administered rats.

    Authors: Carla Ribeiro, Lucieli T Cambri, Rodrigo A Dalia, Michel B Araújo, Ana C Ghezzi, Leandro P Moura, Gustavo G Araújo, Jose D Botezelli and Maria AR Mello

    Citation: Diabetology & Metabolic Syndrome 2012 4:5

    Content type: Research

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  45. Plasma adiponectin is a significant correlate of the pro-inflammatory cardiometabolic risk profile associated with obesity and type 2 diabetes. Salivary pH is influenced by several cardiometabolic risk compone...

    Authors: Monique Tremblay, Yacine Loucif, Julie Methot, Diane Brisson and Daniel Gaudet

    Citation: Diabetology & Metabolic Syndrome 2012 4:4

    Content type: Research

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