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  1. To study mortality rates among patients with diabetes and concomitant atrial fibrillation (AF), prescribed different cardiovascular drugs in primary health care.

    Authors: Per Wändell, Axel C Carlsson, Jan Sundquist, Sven-Erik Johansson, Matteo Bottai and Kristina Sundquist

    Citation: Diabetology & Metabolic Syndrome 2014 6:2

    Content type: Research

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  2. Metabolic syndrome (MS) is a condition associated with obesity that identifies individuals with increased cardiovascular risk. Gastric bypass improves several MS components, such as glucose, lipid metabolism a...

    Authors: Mário Nora, Marta Guimarães, Rui Almeida, Paulo Martins, Gil Gonçalves, Mariana Santos, Tiago Morais, Cláudia Freitas and Mariana P Monteiro

    Citation: Diabetology & Metabolic Syndrome 2014 6:1

    Content type: Research

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  3. Regional differences in the clinical care of Type 1 diabetes (T1D) in Brazil have been recently described. This study aimed to estimate the costs of T1D from the public health care system’s perspective across ...

    Authors: Roberta Arnoldi Cobas, Marcos Bosi Ferraz, Alessandra Saldanha de Mattos Matheus, Lucianne Righeti Monteiro Tannus, Aline Tiemi Kano Silva, Luiz Antonio de Araujo, Carlos Antonio Negrato, Sérgio Atala Dib and Marilia Brito Gomes

    Citation: Diabetology & Metabolic Syndrome 2013 5:83

    Content type: Research

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  4. Several studies point to a correlation between obesity and the severity of depressive and anxiety symptoms in children and adults, but there are still some controversial points about this association. The aim ...

    Authors: Erika P Guedes, Eduardo Madeira, Thiago T Mafort, Miguel Madeira, Rodrigo O Moreira, Laura MC Mendonça, Amélio F Godoy-Matos, Agnaldo J Lopes and Maria Lucia F Farias

    Citation: Diabetology & Metabolic Syndrome 2013 5:82

    Content type: Research

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  5. This study aimed at investigating whether impaired fasting glucose (IFG) is an independent risk factor for incident hypertension among middle-aged Japanese subjects with optimal blood pressure (OBP).

    Authors: Masaaki Morio, Machiko Inoue, Kazuo Inoue and Kimihiko Akimoto

    Citation: Diabetology & Metabolic Syndrome 2013 5:81

    Content type: Short report

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  6. The use of diuretics for hypertension has been associated with unfavorable changes in cardiovascular risk factors, such as uric acid and glucose tolerance, though the findings in the literature are contradictory.

    Authors: Silvio Buscemi, Antonio Nicolucci, Giuseppe Lucisano, Fabio Galvano, Giuseppe Grosso, Fatima M Massenti, Emanuele Amodio, Alice Bonura, Delia Sprini and Giovam B Rini

    Citation: Diabetology & Metabolic Syndrome 2013 5:80

    Content type: Research

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  7. Peroxisome proliferator-activated receptor gamma (PPARγ) has direct and indirect function in adipokines production process. We aimed to assess the possible influence of circulating PPARγ on relative risk of me...

    Authors: Khadijeh Mirzaei, Arash Hossein-nezhad, Seyed Ali Keshavarz, Fariba Koohdani, Ali Akbar Saboor-Yaraghi, Saeed Hosseini, Mohammad Reza Eshraghian and Mahmoud Djalali

    Citation: Diabetology & Metabolic Syndrome 2013 5:79

    Content type: Research

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  8. A residual risk of cardiovascular disease tends to persist despite standard prevention therapy with statins. This may stem partly from increased oxidized low-density lipoprotein (LDL) levels. However, how oxid...

    Authors: Morihiro Matsuda, Ritsu Tamura, Kotaro Kanno, Takatsugu Segawa, Haruyuki Kinoshita, Orie Nishimoto, Hirohiko Nishiyama and Toshiharu Kawamoto

    Citation: Diabetology & Metabolic Syndrome 2013 5:77

    Content type: Research

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  9. Diabetes mellitus, as a risk factor for endometrial cancer (EC), causes an increase in insulin and IGF-1 concentrations in the blood serum. The increase in insulin and IGF-1 are considered mitogenic factors co...

    Authors: Anna Markowska, Monika Pawałowska, Violetta Filas, Konstanty Korski, Marian Gryboś, Stefan Sajdak, Anita Olejek, Wiesława Bednarek, Beata Śpiewankiewicz, Jolanta Lubin and Janina Markowska

    Citation: Diabetology & Metabolic Syndrome 2013 5:76

    Content type: Research

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  10. Several studies highlight curcumin’s benefit as a hypoglycemic agent, however; a limited number of reports present the importance of curcumin in improvement of pancreatic islets in diabetes. The aim of the pre...

    Authors: Mohamed T Abdel Aziz, Mohamed F El-Asmar, Ameen M Rezq, Soheir M Mahfouz, Mohamed A Wassef, Hanan H Fouad, Hanan H Ahmed and Fatma M Taha

    Citation: Diabetology & Metabolic Syndrome 2013 5:75

    Content type: Research

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  11. Body mass index (BMI) and waist circumference (WC) are the most used anthropometric measures to identify obesity. While BMI is considered to be a simple and accurate estimate of general adiposity, WC is an alt...

    Authors: Márcio Weissheimer Lauria, Lívia Maria Pinheiro Moreira, George Luiz Lins Machado-Coelho, Raimundo Marques do Nascimento Neto, Maria Marta Sarquis Soares and Adauto Versiani Ramos

    Citation: Diabetology & Metabolic Syndrome 2013 5:74

    Content type: Research

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  12. The purpose of this study was to explore the extent of associations of cardiovascular autonomic neuropathy (CAN) with metabolic syndrome (MetS) and resting heart reate (HR), and to evaluate the predictive valu...

    Authors: Yu Lu, Zi-Hui Tang, Fangfang Zeng, Yiming Li and Linuo Zhou

    Citation: Diabetology & Metabolic Syndrome 2013 5:73

    Content type: Research

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  13. Abdominal obesity and insulin resistance (IR) place youth at higher risk for premature cardiovascular disease (CVD), but the underlying mechanisms are not clear. In adults, abdominal obesity and IR contribute ...

    Authors: Justin R Ryder, Sonia Vega-López, Constantine S Djedjos and Gabriel Q Shaibi

    Citation: Diabetology & Metabolic Syndrome 2013 5:72

    Content type: Short report

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  14. The aim of this study is to assess the association between the degree of insulin resistance and the different components of the metabolic syndrome among Chinese children and adolescents. Moreover, to determine...

    Authors: Jinhua Yin, Ming Li, Lu Xu, Ying Wang, Hong Cheng, Xiaoyuan Zhao and Jie Mi

    Citation: Diabetology & Metabolic Syndrome 2013 5:71

    Content type: Research

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  15. Metformin treatment has been the most recommended monotherapy of type 2 diabetes mellitus (T2DM) for decades but is challenged by new antidiabetic drugs. This study conducted a meta-analysis of randomized cont...

    Authors: Hongmei Zhu, Shuang Zhu, Xiuqian Zhang, Yang Guo, Yunzhen Shi, Zhimin Chen and Siu-wai Leung

    Citation: Diabetology & Metabolic Syndrome 2013 5:70

    Content type: Research

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  16. It is unclear if the sugar intake may affect metabolic parameters in individuals with type 1 diabetes. Therefore, the purpose of this study was to evaluate the effects of sucrose intake in glycemic, lipemic, a...

    Authors: Débora Lopes Souto, Lenita Zajdenverg, Melanie Rodacki and Eliane Lopes Rosado

    Citation: Diabetology & Metabolic Syndrome 2013 5:67

    Content type: Research

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  17. There is lack of consensus concerning the best screening strategy for gestational diabetes (GDM). The aim of our survey was therefore to investigate attitudes and practices of all obstetrical centers in the no...

    Authors: Katrien Benhalima, Paul Van Crombrugge, Roland Devlieger, Johan Verhaeghe, Ann Verhaegen, Luc De Catte and Chantal Mathieu

    Citation: Diabetology & Metabolic Syndrome 2013 5:66

    Content type: Research

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  18. The purpose of this study is to investigate the association of metabolic syndrome (MS) and its components with the risk of impaired glucose tolerance (IGT) in high risk urban professionals. The goal is to impr...

    Authors: Ping Zeng, Xuefeng Zhu, Yi Zhang, Sinan Wu, Jun Dong, Tiemei Zhang and Shu Wang

    Citation: Diabetology & Metabolic Syndrome 2013 5:65

    Content type: Research

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  19. Oral health complications in diabetes and hypertension include decreased salivary secretion. The sodium-glucose cotransporter 1 (SGLT1) protein, which transports 1 glucose/2 Na+/264 H2O molecules, is described in...

    Authors: Robinson Sabino-Silva, Maristela Mitiko Okamoto, Aline David-Silva, Rosana Cristina Mori, Helayne Soares Freitas and Ubiratan Fabres Machado

    Citation: Diabetology & Metabolic Syndrome 2013 5:64

    Content type: Short report

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  20. Current International Diabetes Federation guidelines recommend a target HbA1c <7.0%, but many people with diabetes worldwide find this difficult to achieve, increasing their risk of developing complications. This...

    Authors: Leon Litwak, Su-Yen Goh, Zanariah Hussein, Rachid Malek, Vinay Prusty and Mohammad E Khamseh

    Citation: Diabetology & Metabolic Syndrome 2013 5:57

    Content type: Research

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  21. The pathogenesis between cerebral vascular disease (CVD) and the endothelial dysfunction (ETD) remains elusive in diabetes. Therefore, we investigated the expression of partial vasoactivators which be closely ...

    Authors: Renshi Xu, Rongwei Yang, Huoyou Hu, Qiujiang Xi, Hui Wan and Yuchen Wu

    Citation: Diabetology & Metabolic Syndrome 2013 5:63

    Content type: Research

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  22. The importance of tight blood glucose control among outpatients with diabetes mellitus is well established, however, the management of diabetes in the hospital setting is generally considered secondary in impo...

    Authors: Edson Duarte Moreira Jr, Patricia Carvalho Balthazar Silveira, Raimundo Celestino Silva Neves, Clodoaldo Souza Jr, Zaira Onofre Nunes and Maria da Conceição C Almeida

    Citation: Diabetology & Metabolic Syndrome 2013 5:62

    Content type: Research

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    The Erratum to this article has been published in Diabetology & Metabolic Syndrome 2013 5:78

  23. Neonatal STZ treatment induces a state of mild hyperglycemia in adult rats that disrupts metabolism and maternal/fetal interactions. The aim of this study was investigate the effect of neonatal STZ treatment o...

    Authors: Ana Carolina Inhasz Kiss, Barbara Woodside, Yuri Karen Sinzato, Maria Martha Bernardi, Wilma De Grava Kempinas, Janete Aparecida Anselmo-Franci and Débora Cristina Damasceno

    Citation: Diabetology & Metabolic Syndrome 2013 5:61

    Content type: Research

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  24. Both physical activity and inflammation are important in the pathophysiology of metabolic syndrome (MetS). Our study aim is to explore their associations in an elderly male (≥ 65 years old) cohort.

    Authors: Chia-Ling Chang, Po-Tseng Lee, Wei-Ting Chang, Chin-Sung Chang, Jyh-Hong Chen, Liang-Miin Tsai, Chih-Hsing Wu and Ping-Yen Liu

    Citation: Diabetology & Metabolic Syndrome 2013 5:60

    Content type: Research

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  25. The prevalence of undiagnosed diabetes mellitus (DM) in Greenland has been reported very high with only 30% of cases diagnosed. In 2010, glycosylated hemoglobin (A1C) was introduced as a diagnostic tool in Gre...

    Authors: Line Damsgaard and Michael Lynge Pedersen

    Citation: Diabetology & Metabolic Syndrome 2013 5:59

    Content type: Research

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  26. Diabetes mellitus (DM) and thyroid dysfunction (TD) are the two most common endocrine disorders in clinical practice. The unrecognized TD may adversely affect the metabolic control and add more risk to an alre...

    Authors: Cátia Cristina Silva Sousa Vergara Palma, Marco Pavesi, Verônica Guedes Nogueira, Eliete Leão Silva Clemente, Maria de Fátima Bevilacqua Motta Pereira Vasconcellos, Luiz Carlos Pereira Júnior, Fernanda Faissol Pacheco, Tássia Gomide Braga, Ludmila de Faria Bello, Juliana Oliveira Soares, Stefanie Cathren Fenizola dos Santos, Vinícius Paes Leme Cavalcante Campos and Marília Brito Gomes

    Citation: Diabetology & Metabolic Syndrome 2013 5:58

    Content type: Research

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  27. Obesity is common in type 2 diabetes (T2DM) and is associated with increased risk of morbidity and all-cause mortality. This analysis describes weight changes associated with insulin detemir initiation in real...

    Authors: Jean-François Yale, Taner Damci, Marcel Kaiser, Eddy Karnieli, Kamlesh Khunti, Andreas Liebl, Florian MM Baeres, Anne Louise Svendsen and Stuart A Ross

    Citation: Diabetology & Metabolic Syndrome 2013 5:56

    Content type: Research

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  28. The purpose of this study is to evaluate the relationship between glycemic control and the factors of knowledge about diabetes, resilience, depression and anxiety among Brazilian adolescents and young adults w...

    Authors: Fabio R Munhoz Santos, Viviane Bernardo, Monica A L Gabbay, Sergio A Dib and Daniel Sigulem

    Citation: Diabetology & Metabolic Syndrome 2013 5:55

    Content type: Research

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  29. To evaluate possible associations between cardiovascular autonomic dysfunction and peripheral artery disease (PAD) in patients with type 2 diabetes mellitus.

    Authors: Luís Henrique Canani, Eduardo Copstein, Miriam Pecis, Rogério Friedman, Cristiane Bauermann Leitão, Mirela Jobim Azevedo, Cristina Triches, Dimitris Rucks Varvaki Rados, Ruy Silveira Moreas and Jorge Luiz Gross

    Citation: Diabetology & Metabolic Syndrome 2013 5:54

    Content type: Research

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  30. It has been hypothesized that fatty acids derived from a diet high in saturated fat may negatively affect endothelial function more significantly than a diet high in unsaturated fat; nevertheless, the effects ...

    Authors: Hady Keita, Eduardo Ramírez-San Juan, Norma Paniagua-Castro, Leticia Garduño-Siciliano and Lucía Quevedo

    Citation: Diabetology & Metabolic Syndrome 2013 5:53

    Content type: Research

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  31. Hypertension frequently coexists with type 2 diabetes (DM), and increases the risk of cardiovascular outcomes. The aim of the study was to obtain/maintain blood pressure (BP) goals (ADA/JNC 7) according to a s...

    Authors: Luciana V Viana, Cristiane B Leitão, Maria F Grillo, Ennio P C C Rocha, Juliana K Brenner, Rogerio Friedman and Jorge L Gross

    Citation: Diabetology & Metabolic Syndrome 2013 5:52

    Content type: Research

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  32. CD36, a class B scavenger receptor, participates in the pathogenesis of metabolic dysregulation such as insulin resistance, hepatic steatosis, and atherosclerosis. Persistent hepatitis C virus (HCV) infection ...

    Authors: Takashi Himoto, Joji Tani, Hisaaki Miyoshi, Asahiro Morishita, Hirohito Yoneyama, Kazutaka Kurokohchi, Michio Inukai, Hisashi Masugata, Fuminori Goda, Shoichi Senda, Reiji Haba, Masaki Ueno, Genji Yamaoka and Tsutomu Masaki

    Citation: Diabetology & Metabolic Syndrome 2013 5:51

    Content type: Research

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  33. Brazil is expected to have 19.6 million patients with diabetes by the year 2030. A key concept in the treatment of type 2 diabetes mellitus (T2DM) is establishing individualized glycemic goals based on each pa...

    Authors: Marcos Antônio Tambascia, Márcia Nery, Jorge Luiz Gross, Mariana Narbot Ermetice and Carolina Piras de Oliveira

    Citation: Diabetology & Metabolic Syndrome 2013 5:50

    Content type: Review

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  34. During our phylogenetic evolution we have selected genes, the so called thrifty genes, that can help to maximize the amount of energy stored from every consumed calorie. An imbalance in the amount of stored ca...

    Authors: Carlos Antonio Negrato and Marilia Brito Gomes

    Citation: Diabetology & Metabolic Syndrome 2013 5:49

    Content type: Review

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    The Retraction Note to this article has been published in Diabetology & Metabolic Syndrome 2014 6:60

  35. The single-center, open-label, four-arm, exploratory study investigates the relation of different anti-diabetics to serum levels of active TGF-β, a known pro-fibrotic stimulus, before and after a defined test ...

    Authors: Stefan Pscherer, Thomas Freude, Thomas Forst, Andreas K Nussler, Karl F Braun and Sabrina Ehnert

    Citation: Diabetology & Metabolic Syndrome 2013 5:48

    Content type: Short report

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  36. Current gold standard therapeutic strategies for T2DM target insulin resistance or β cell dysfunction as their core mechanisms of action. However, the use of traditional anti-diabetic drugs, in most cases, doe...

    Authors: Asfandyar Sheikh

    Citation: Diabetology & Metabolic Syndrome 2013 5:47

    Content type: Review

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  37. The Brazilian Study on the Practice of Diabetes Care main objective was to provide an epidemiological profile of individuals with type 1 and 2 diabetes mellitus (DM) in Brazil, concerning therapy and adherence...

    Authors: Juarez R Braga, Alvaro Avezum, Sandra RG Ferreira and Adriana Forti

    Citation: Diabetology & Metabolic Syndrome 2013 5:46

    Content type: Research

    Published on:

  38. Independent of other cardiovascular (CV) risk factors, increased arterial stiffness has been established as a predictor of morbidity and mortality. The main aim of this study was to investigate the impact of d...

    Authors: Rafael de Oliveira Alvim, Paulo Caleb Junior Lima Santos, Mariane Manso Musso, Roberto de Sá Cunha, José Eduardo Krieger, José Geraldo Mill and Alexandre Costa Pereira

    Citation: Diabetology & Metabolic Syndrome 2013 5:45

    Content type: Research

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  39. We aimed to explore the association between presence and number of components of the Metabolic Syndrome (MetS) and subclinical atherosclerosis outcomes (common carotid intima media thickness, plaque presence a...

    Authors: Andrie G Panayiotou, Maura Griffin, Panayiotis Kouis, Theodosis Tyllis, Niki Georgiou, Dawn Bond and Andrew N Nicolaides

    Citation: Diabetology & Metabolic Syndrome 2013 5:44

    Content type: Research

    Published on:

  40. The aim of this study is to compare the efficacy of intensification of insulin treatment with insulin glargine and biphasic human insulin in patients with type 2 diabetes on concomitant therapy with oral antid...

    Authors: Nicholas Tentolouris, Venetsana Kyriazopoulou, Dimitrios Makrigiannis and Barbara Baroutsou

    Citation: Diabetology & Metabolic Syndrome 2013 5:43

    Content type: Research

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  41. The worldwide epidemic of diabetes and obesity has resulted in a rapid upsurge in the prevalence of metabolic syndrome (MetS). MetS makes the individual liable to endothelial dysfunction which can initiate sex...

    Authors: Nafiu Amidu, William KBA Owiredu, Huseini Alidu, Charity Sarpong, Christian K Gyasi-Sarpong and Lawrence Quaye

    Citation: Diabetology & Metabolic Syndrome 2013 5:42

    Content type: Research

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  42. The phosphodiesterase inhibitor cilostazol has beneficial effects on atherosclerosis by virtue of vasodilatory and antiplatelet effects. However, less is known about the effect of cilostazol on arterial stiffn...

    Authors: Nam Hoon Kim, Hee Young Kim, Hyonggin An, Ji A Seo, Nan Hee Kim, Kyung Mook Choi, Sei Hyun Baik, Dong Seop Choi and Sin Gon Kim

    Citation: Diabetology & Metabolic Syndrome 2013 5:41

    Content type: Research

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  43. Quantitation of β-cell function is critical in better understanding of the dynamic interactions of insulin secretion, clearance and action at different phases in the progression of diabetes. The present study ...

    Authors: Xiaoli Wang, Barbara C Hansen, Da Shi, Yupeng Fang, Fenglai Du, Bingdi Wang, Yaxiong Michael Chen, Francine M Gregoire and Yi-Xin Jim Wang

    Citation: Diabetology & Metabolic Syndrome 2013 5:40

    Content type: Research

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  44. Diabetes mellitus is a chronic disease that necessitates continuing treatment and patient self-care education. Monitoring of blood glucose to near normal level without hypoglycemia becomes a challenge in the m...

    Authors: Nalinee Poolsup, Naeti Suksomboon and Aye Mon Kyaw

    Citation: Diabetology & Metabolic Syndrome 2013 5:39

    Content type: Research

    Published on:

  45. Glucose variability could be an independent risk factor for diabetes complications in addition to average glucose. The deficiency in islet β cell secretion and insulin sensitivity, the two important pathophysi...

    Authors: Tong Chen, Feng Xu, Jian-bin Su, Xue-qin Wang, Jin-feng Chen, Gang Wu, Yan Jin and Xiao-hua Wang

    Citation: Diabetology & Metabolic Syndrome 2013 5:38

    Content type: Research

    Published on:

  46. Hispanics have a high rate of diabetes that exposes them to an increased risk of cardiovascular disease. We hypothesized that many of the pathophysiological mechanisms that cause atherosclerotic disease may be...

    Authors: Carlos O Mendivil, Ludivina Robles-Osorio, Edward S Horton, Osama Hamdy and Augusto Enrique Caballero

    Citation: Diabetology & Metabolic Syndrome 2013 5:37

    Content type: Research

    Published on:

  47. To investigate the predictive value of different biomarkers for the incidence of type 2 diabetes mellitus (T2DM) in subjects with metabolic syndrome.

    Authors: Michal Ozery-Flato, Naama Parush, Tal El-Hay, Žydrūnė Visockienė, Ligita Ryliškytė, Jolita Badarienė, Svetlana Solovjova, Milda Kovaitė, Rokas Navickas and Aleksandras Laucevičius

    Citation: Diabetology & Metabolic Syndrome 2013 5:36

    Content type: Research

    Published on:


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