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  1. Adult-onset autoimmune diabetes (AID) has two different phenotypes: classic type 1 diabetes mellitus (T1DM), with insulin requirement just after diagnosis, and latent autoimmune diabetes in adults (LADA). The ...

    Authors: Lúcia Fadiga, Joana Saraiva, Diana Catarino, João Frade, Miguel Melo and Isabel Paiva

    Citation: Diabetology & Metabolic Syndrome 2020 12:107

    Content type: Research

    Published on:

  2. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Zahra Aslani, Omid Sadeghi, Motahar Heidari-Beni, Hoda Zahedi, Fereshteh Baygi, Nitin Shivappa, James R. Hébert, Sajjad Moradi, Gity Sotoudeh, Hamid Asayesh, Shirin Djalalinia and Mostafa Qorbani

    Citation: Diabetology & Metabolic Syndrome 2020 12:106

    Content type: Correction

    Published on:

    The original article was published in Diabetology & Metabolic Syndrome 2020 12:86

  4. Aim of this study is to investigate a possible association of hypoglycemic episodes and arterial hypertension. We hypothesize that hospitalized insulin-treated diabetes patients with hypertensive crisis have m...

    Authors: Abimbola Abobarin-Adeagbo, Andreas Wienke, Matthias Girndt and Rainer U. Pliquett

    Citation: Diabetology & Metabolic Syndrome 2020 12:104

    Content type: Research

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  5. Diabetes mellitus (DM) is associated with adverse outcomes, and visceral adipose tissue (VAT), classified into intraperitoneal VAT (IVAT) and retroperitoneal VAT (RVAT), is associated with insulin resistance. ...

    Authors: Muhei Tanaka, Hiroshi Okada, Yoshitaka Hashimoto, Muneaki Kumagai, Hiromi Nishimura and Michiaki Fukui

    Citation: Diabetology & Metabolic Syndrome 2020 12:103

    Content type: Research

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  6. Long QT interval (QT) and abnormal QT dispersion (QTd) are associated with sudden death. The relationship between cardiac autonomic neuropathy (CAN) and QT indices in type 2 diabetic patients were investigated.

    Authors: Maryam Vasheghani, Farzaneh Sarvghadi, Mohammad Reza Beyranvand and Habib Emami

    Citation: Diabetology & Metabolic Syndrome 2020 12:102

    Content type: Research

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  7. There is a lack of studies examining the association between Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) and metabolic syndrome (MetS) and obesity. Thus, this study aimed to investigate ...

    Authors: Saba Mohammadpour, Parivash Ghorbaninejad, Nasim Janbozorgi and Sakineh Shab-Bidar

    Citation: Diabetology & Metabolic Syndrome 2020 12:101

    Content type: Research

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  8. Multiple epidemiological studies were conducted amongst a variety of ethnic groups and showed discrepancies in the prevalence of metabolic syndrome (MeS) and its individual components. This study aimed to dete...

    Authors: Kamel Ajlouni, Yousef Khader, Mohamad Alyousfi, Mohannad Al Nsour, Anwar Batieha and Hashem Jaddou

    Citation: Diabetology & Metabolic Syndrome 2020 12:100

    Content type: Research

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  9. A low-grade inflammation is associated with cardiac autonomic neuropathy (CAN) and increased concentration of leukotriene B4 (LTB4) was found in individuals with type 1 diabetes and definitive CAN. This cross-...

    Authors: Jose Antonio Januario Neves, Mozânia Reis De Matos, Theresa Ramalho, Daniele Pereira Santos-Bezerra, Cristiane Das Graças Dias Cavalcante, Renata D’ Alpino Peixoto, Márcia Silva Queiroz, Sonia Jancar and Maria Lucia Correa-Giannella

    Citation: Diabetology & Metabolic Syndrome 2020 12:99

    Content type: Short report

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  10. Research on intestinal microbiota has grown considerably, as well as the interest on probiotics’ supplementation effects on metabolism. Considering high prevalence rates of metabolic diseases linked by insulin...

    Authors: Bárbara Izabel Moraes Salles, Débora Cioffi and Sandra Roberta G. Ferreira

    Citation: Diabetology & Metabolic Syndrome 2020 12:98

    Content type: Review

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  11. Type 2 diabetes mellitus (T2DM) is a complex polygenic metabolic disease characterized by elevated blood glucose. Multiple environmental and genetic factors can increase the risk of T2DM and its complications,...

    Authors: Cuilin Li, Yuping Yang, Xin Liu, Zhongyu Li, Hong Liu and Qiuhong Tan

    Citation: Diabetology & Metabolic Syndrome 2020 12:97

    Content type: Review

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  12. Cardiovascular disease is the cause of more than 50% of mortalities globally, and this rate has grown by 8.6% since the 60 s. One of the risk factors associated with cardiovascular disease and its resulting mo...

    Authors: Nader Salari, Peyman Kaikhosro Doulatyari, Alireza Daneshkhah, Aliakbar Vaisi-Raygani, Rostam Jalali, Parnian kord Jamshidi, Alireza Abdi, Masoud Mohammadi and Mohsen Kazeminia

    Citation: Diabetology & Metabolic Syndrome 2020 12:96

    Content type: Research

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  13. Metabolic syndrome (MetS) has been related to the pathogenesis of variety categories of cancers. This meta-analysis aimed to determine the association between MetS and the incidence of lung cancer.

    Authors: Li Qiao, Deliang Ma, Hui Lv, Ding Shi, Min Fei, Yu Chen, Fei Xie, Zhuoyan Wang, Ying Wang, Wanhua Liang and Peiying Hu

    Citation: Diabetology & Metabolic Syndrome 2020 12:95

    Content type: Research

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  14. Female sexual dysfunction (FSD) is one of the chronic complications of diabetes as is male sexual dysfunction, but the former is less studied. Therefore, the aim of this study was to assess of the prevalence a...

    Authors: Adriana Gherbon, Mirela Frandes, Deiana Roman, Diana Anastasiu-Popov and Romulus Timar

    Citation: Diabetology & Metabolic Syndrome 2020 12:94

    Content type: Research

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  15. Metabolic syndrome (MetS) is a clustering of cardiovascular risk factors, which is rising in the low and middle income countries (LMICs). There are various studies with inconsistent findings that are inconclus...

    Authors: Zebenay Workneh Bitew, Ayinalem Alemu, Ermias Getaneh Ayele, Zelalem Tenaw, Anmut Alebel and Teshager Worku

    Citation: Diabetology & Metabolic Syndrome 2020 12:93

    Content type: Research

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  16. We aimed to evaluate the effects of short-term therapy with dapagliflozin on serum uric acid (SUA) and urinary uric acid (UUA) levels in patients with type 2 diabetes.

    Authors: Tao Yuan, Shixuan Liu, Yingyue Dong, Yong Fu, Yan Tang and Weigang Zhao

    Citation: Diabetology & Metabolic Syndrome 2020 12:92

    Content type: Research

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  17. People with obesity have a compromised browning capacity of adipose tissue when faced with sympathetic stimuli. This study aimed to determine whether norepinephrine treatment can enhance the induction of precu...

    Authors: Yao Qiu, Lizhi Sun, Xiaolin Hu, Xin Zhao, Hongyan Shi, Zhao Liu and Xiao Yin

    Citation: Diabetology & Metabolic Syndrome 2020 12:91

    Content type: Research

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  18. To examine the effects of gastric bypass surgery on health-related quality of life (HRQoL) in obese patients with type 2 diabetes, and to investigate their experiences of life adjustments using quantitative an...

    Authors: Petros Katsogiannos, Eva Randell, Magnus Sundbom, Andreas Rosenblad, Jan W. Eriksson and Janeth Leksell

    Citation: Diabetology & Metabolic Syndrome 2020 12:90

    Content type: Research

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  19. Brazil is one of top 10 countries with the highest number of people with diabetes mellitus (DM), affecting 16.8 million peoples. It is estimated that 7.7 million people (20–79 years) in the country have not ye...

    Authors: Cassyano J. Correr, Wendel Coura-Vital, Josélia C. Q. P. Frade, Renata C. R. M. Nascimento, Lúbia G. Nascimento, Eliete B. Pinheiro, Wesley M. Ferreira, Janice S. Reis, Karla F. S. Melo, Roberto Pontarolo, Mônica S. A. Lenzi, José V. Almeida, Hermelinda C. Pedrosa and Walter S. J. João

    Citation: Diabetology & Metabolic Syndrome 2020 12:89

    Content type: Research

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  20. The influence of pre-pregnancy body mass index (BMI) and gestational weight gain (GWG) on perinatal outcomes of women with polycystic ovary syndrome (PCOS) remains unclear. Therefore, we explored how the above...

    Authors: Lirui Zhang, Wei Zheng, Cheng Liu, Xin Liang, Li Zhang, Zhihong Tian and Guanghui Li

    Citation: Diabetology & Metabolic Syndrome 2020 12:88

    Content type: Research

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  22. The association of dietary inflammatory index (DII®), as an index of inflammatory quality of diet, with cardiometabolic diseases (CMDs) and risk factors (CMRFs) has been inconsistent in previous studies.

    Authors: Zahra Aslani, Omid Sadeghi, Motahar Heidari-Beni, Hoda Zahedi, Fereshteh Baygi, Nitin Shivappa, James R. Hébert, Sajjad Moradi, Gity Sotoudeh, Hamid Asayesh, Shirin Djalalinia and Mostafa Qorbani

    Citation: Diabetology & Metabolic Syndrome 2020 12:86

    Content type: Review

    Published on:

    The Correction to this article has been published in Diabetology & Metabolic Syndrome 2020 12:106

  23. HbA1c variability has been linked to retinopathy, renal disease and autonomic neuropathy in patients with type 1 diabetes mellitus (T1D) and type 2 diabetes mellitus (T2D). Although the same relationship has b...

    Authors: M. V. Pinto, L. C. G. F. Rosa, L. F. Pinto, J. R. Dantas, G. F. Salles, L. Zajdenverg, M. Rodacki and M. A. Lima

    Citation: Diabetology & Metabolic Syndrome 2020 12:85

    Content type: Short report

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  24. Risk scores were mainly proved to predict undiagnosed type 2 diabetes mellitus (UT2DM) in a non-invasive manner and to guide earlier clinical treatment. The objective of the present study was to assess the per...

    Authors: Maher Abdallah, Safa Sharbaji, Marwa Sharbaji, Zeina Daher, Tarek Faour, Zeinab Mansour and Mohammad Hneino

    Citation: Diabetology & Metabolic Syndrome 2020 12:84

    Content type: Research

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  25. Insulin resistance can occur in all metabolic organs including the liver, adipose tissue, and skeletal muscles. Circulating soluble epidermal growth factor receptor (soluble EGFR) and adipsin levels are altere...

    Authors: Mayu Kyohara, Jun Shirakawa, Tomoko Okuyama, Yu Togashi, Ryota Inoue, Jinghe Li, Daisuke Miyashita and Yasuo Terauchi

    Citation: Diabetology & Metabolic Syndrome 2020 12:83

    Content type: Research

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  26. Melatonin has been shown to increase brown adipose tissue (BAT) mass, which can lead to important metabolic effects, such as bodyweight reduction and glycemic improvement. However, BAT mass can only be measure...

    Authors: Bruno Halpern, Marcio C. Mancini, Caroline Mendes, Camila Maria Longo Machado, Silvana Prando, Marcelo Tatit Sapienza, Carlos Alberto Buchpiguel, Fernanda Gaspar do Amaral and José Cipolla-Neto

    Citation: Diabetology & Metabolic Syndrome 2020 12:82

    Content type: Short report

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  27. Whether polymorphisms in tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), interleukin-10 (IL-10) or adiponectin (ADIPOQ) influence the risk of gestational diabetes mellitus (GDM) or not remain inconclusive....

    Authors: Qiqi Huang, Yi Wang, Binbin Gu and Yanwen Xu

    Citation: Diabetology & Metabolic Syndrome 2020 12:81

    Content type: Research

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  28. The disclosure in the media of a benefit with the use of dexamethasone in patients with COVID-19 infection sets precedents for self-medication and inappropriate use of corticosteroids.

    Authors: Janine Alessi, Giovana B. de Oliveira, Beatriz D. Schaan and Gabriela H. Telo

    Citation: Diabetology & Metabolic Syndrome 2020 12:80

    Content type: Review

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  29. Patients with severe mental illness (SMI) are at increased risk of developing non-communicable diseases that could cause significantly lower life expectancy when compared to the general population. This study ...

    Authors: Agete Tadewos Hirigo and Tesfaye Teshome

    Citation: Diabetology & Metabolic Syndrome 2020 12:79

    Content type: Research

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  30. Pioglitazone, as a PPAR gamma agonist, is used for the management of type 2 diabetes mellitus. Nevertheless, evidence showed that the therapeutic modulation of PPAR gamma activity using pioglitazone might be l...

    Authors: Ahmad Gholami, Mohammad Hossein Dabbaghmanesh, Younes Ghasemi, Pedram Talezadeh, Farhad Koohpeyma and Nima Montazeri-Najafabady

    Citation: Diabetology & Metabolic Syndrome 2020 12:78

    Content type: Research

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  31. It has been reported that long non-coding RNAs (lncRNAs) play vital roles in diabetic nephropathy (DN). Our study aims to research the function of lncRNA KCNQ1OT1 in DN cells and the molecular mechanism.

    Authors: Ran Jie, Pengpeng Zhu, Jiao Zhong, Yan Zhang and Hongyan Wu

    Citation: Diabetology & Metabolic Syndrome 2020 12:77

    Content type: Research

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  32. In patients with diabetes, the prevalence of depression and anxiety symptoms is about two to four times greater than in the general population. The association between diabetes and mental health disorders coul...

    Authors: Janine Alessi, Giovana Berger de Oliveira, Debora Wilke Franco, Bibiana Brino do Amaral, Alice Scalzilli Becker, Carolina Padilla Knijnik, Gabriel Luiz Kobe, Taíse Rosa de Carvalho, Guilherme Heiden Telo, Beatriz D. Schaan and Gabriela Heiden Telo

    Citation: Diabetology & Metabolic Syndrome 2020 12:76

    Content type: Research

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  33. The aim of this study is to evaluate the impact of diabetes, hypertension, cardiovascular disease and the use of angiotensin converting enzyme inhibitors/angiotensin II receptor blockers (ACEI/ARB) with severi...

    Authors: Bianca de Almeida-Pititto, Patrícia M. Dualib, Lenita Zajdenverg, Joana Rodrigues Dantas, Filipe Dias de Souza, Melanie Rodacki and Marcello Casaccia Bertoluci

    Citation: Diabetology & Metabolic Syndrome 2020 12:75

    Content type: Research

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  34. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Claudia Jara, Felipe Oyarzun-Ampuero, Flavio Carrión, Esteban González-Echeverría, Claudio Cappelli and Pablo Caviedes

    Citation: Diabetology & Metabolic Syndrome 2020 12:74

    Content type: Correction

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    The original article was published in Diabetology & Metabolic Syndrome 2020 12:66

  35. Patients with type 2 diabetes mellitus (T2DM) are characterized by chronic hyperglycemia as a consequence of decreased insulin sensitivity, which contributes to bone demineralization and could also be related ...

    Authors: J. I. Aguayo-Ruiz, T. A. García-Cobián, S. Pascoe-González, S. Sánchez-Enríquez, I. M. Llamas-Covarrubias, T. García-Iglesias, A. López-Quintero, M. A. Llamas-Covarrubias, J. Trujillo-Quiroz and E. A. Rivera-Leon

    Citation: Diabetology & Metabolic Syndrome 2020 12:73

    Content type: Research

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  36. Undercarboxylated osteocalcin (ucOC) is a secreted protein produced by osteoblasts that regulates insulin secretion and insulin sensitivity in rodents. However, the significance of these effects on glucose met...

    Authors: Shogo Funakoshi, Kumiko Yoshimura, Seiki Hirano, Satoko Ohmi, Eri Amano, Yoshiharu Fukuda, Yoshio Terada and Shimpei Fujimoto

    Citation: Diabetology & Metabolic Syndrome 2020 12:72

    Content type: Short report

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  37. Black individuals have a great risk of developing chronic kidney disease (CKD) that is associated with high morbimortality, so it is important to classify them into the correct renal function group. Some equat...

    Authors: Marcela Haas Pizarro, Deborah Conte Santos, Laura Gomes Nunes Melo, Bianca Senger Vasconcelos Barros, Luiza Harcar Muniz, Luís Cristóvão Porto, Dayse Aparecida Silva, Rachel Bregman and Marilia Brito Gomes

    Citation: Diabetology & Metabolic Syndrome 2020 12:71

    Content type: Research

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  38. Treatment indexes using continuous glucose monitoring (CGM) have become standardized internationally, and the use of ambulatory glucose profile (AGP) is currently recommended. However, the relationship between...

    Authors: Akemi Tokutsu, Yosuke Okada, Keiichi Torimoto and Yoshiya Tanaka

    Citation: Diabetology & Metabolic Syndrome 2020 12:70

    Content type: Research

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  39. The regular intake of fiber generates numerous health benefits. However, the efficacy depends on the duration of consumption and the ingested dose. Studies investigating the optimal dose are of interest to ena...

    Authors: Janina de Sales Guilarducci, Breno Augusto Ribeiro Marcelino, Isaac Filipe Moreira Konig, Tamira Maria Orlando, Mary Suzan Varaschin and Luciano José Pereira

    Citation: Diabetology & Metabolic Syndrome 2020 12:69

    Content type: Research

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  40. High glucose (HG) induced podocytes injury plays an important role in diabetes nephropathy (DN) development. Long noncoding RNA cancer susceptibility candidate 2 (CASC2) was found to be decreased in serum of D...

    Authors: Feng Li, Bo Dai and Xiquan Ni

    Citation: Diabetology & Metabolic Syndrome 2020 12:68

    Content type: Research

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  41. The chronic complications of Type 2 Diabetes (T2D) such as macrovascular disease is amplified with the increase in the number of metabolic syndrome (MetS) risk factors. This research aims to study the relation...

    Authors: Riyadh Saif-Ali, Nor Azmi Kamaruddin, Molham AL-Habori, Sami A. Al-Dubai and Wan Zurinah Wan Ngah

    Citation: Diabetology & Metabolic Syndrome 2020 12:67

    Content type: Research

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  42. In type I diabetes mellitus (T1DM) pancreatic β cells are destroyed. Treatment entails exogenous insulin administration and strict diet control, yet optimal glycemic control is hardly attainable. Islet transpl...

    Authors: Claudia Jara, Felipe Oyarzun-Ampuero, Flavio Carrión, Esteban González-Echeverría, Claudio Cappelli and Pablo Caviedes

    Citation: Diabetology & Metabolic Syndrome 2020 12:66

    Content type: Research

    Published on:

    The Correction to this article has been published in Diabetology & Metabolic Syndrome 2020 12:74

  43. Asprosin, a newly identified adipokine, is pathologically increased in individuals with insulin resistance. However, the available evidence on the association of asprosin and type 2 diabetes mellitus (T2DM) st...

    Authors: Shakiba Naiemian, Mohsen Naeemipour, Mehdi Zarei, Moslem Lari Najafi, Ali Gohari, Mohammad Reza Behroozikhah, Hafez Heydari and Mohammad Miri

    Citation: Diabetology & Metabolic Syndrome 2020 12:65

    Content type: Research

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  44. To assess gender differences in Quality of life (QoL) and in sociodemographic, clinical and psychological factors associated with impaired QoL in adults with long-standing type 1 diabetes mellitus (DM1).

    Authors: Ana María Castellano-Guerrero, Raquel Guerrero, Desireé Ruiz-Aranda, Sofia Perea, Alfonso Pumar, Federico Relimpio, Miguel Angel Mangas, Fernando Losada and Maria Asunción Martínez-Brocca

    Citation: Diabetology & Metabolic Syndrome 2020 12:64

    Content type: Research

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  45. Chronic inflammation is involved in the pathogenesis of several metabolic diseases, such as obesity and type 2 diabetes mellitus (T2DM). With the recent worldwide outbreak of coronavirus disease (SARS-CoV-2), ...

    Authors: Mauricio Krause, Fernando Gerchman and Rogério Friedman

    Citation: Diabetology & Metabolic Syndrome 2020 12:63

    Content type: Commentary

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  46. Poor adherence to the medical regimen is a major clinical problem in the management of patients with diabetes. This study sought to investigate the level of medication adherence to antidiabetic therapy and to ...

    Authors: Gebre Teklemariam Demoz, Shishay Wahdey, Degena Bahrey, Halefom Kahsay, Gebremariam Woldu, Yirga Legesse Niriayo and Andrew Collier

    Citation: Diabetology & Metabolic Syndrome 2020 12:62

    Content type: Research

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  47. Chromogranin B (CgB) plays an important role in the physiological insulin secretion of pancreatic beta cells. Serum CgB levels were investigated in type 1 and type 2 diabetes patients in a cross-sectional study.

    Authors: Zoltan Herold, Magdolna Herold, Klara Rosta, Marton Doleschall and Aniko Somogyi

    Citation: Diabetology & Metabolic Syndrome 2020 12:61

    Content type: Short report

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  48. The prevalence of non-alcoholic fatty liver disease (NAFLD) has been increasing rapidly. It is nowadays recognized as the most frequent liver disease, affecting a quarter of global population and regularly coe...

    Authors: Amélio F. Godoy-Matos, Wellington S. Silva Júnior and Cynthia M. Valerio

    Citation: Diabetology & Metabolic Syndrome 2020 12:60

    Content type: Review

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  49. Crocin as a carotenoid exerts anti-oxidant, anti-inflammatory, anti-cancer, neuroprotective and cardioprotective effects. Besides, the increasing prevalence of diabetes mellitus and its allied complications, a...

    Authors: Vahideh Behrouz, Ali Dastkhosh, Mehdi Hedayati, Meghdad Sedaghat, Maryam Sharafkhah and Golbon Sohrab

    Citation: Diabetology & Metabolic Syndrome 2020 12:59

    Content type: Research

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  50. The present study investigated the relationships between psychological stress indices and oxidative stress marker, also when combined with emergent insulin resistance (IR), in the non-diabetic, middle-aged sub...

    Authors: Miroslaw Janczura, Jerzy Dropinski, Anna Gielicz, Katarzyna Kotula-Horowitz, Teresa Iwaniec, Andrzej Stanisz, Rafal Rosa and Teresa B. Domagala

    Citation: Diabetology & Metabolic Syndrome 2020 12:58

    Content type: Research

    Published on:


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