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  1. Chromogranin B (CgB) plays an important role in the physiological insulin secretion of pancreatic beta cells. Serum CgB levels were investigated in type 1 and type 2 diabetes patients in a cross-sectional study.

    Authors: Zoltan Herold, Magdolna Herold, Klara Rosta, Marton Doleschall and Aniko Somogyi

    Citation: Diabetology & Metabolic Syndrome 2020 12:61

    Content type: Short report

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  2. The prevalence of non-alcoholic fatty liver disease (NAFLD) has been increasing rapidly. It is nowadays recognized as the most frequent liver disease, affecting a quarter of global population and regularly coe...

    Authors: Amélio F. Godoy-Matos, Wellington S. Silva Júnior and Cynthia M. Valerio

    Citation: Diabetology & Metabolic Syndrome 2020 12:60

    Content type: Review

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  3. Crocin as a carotenoid exerts anti-oxidant, anti-inflammatory, anti-cancer, neuroprotective and cardioprotective effects. Besides, the increasing prevalence of diabetes mellitus and its allied complications, a...

    Authors: Vahideh Behrouz, Ali Dastkhosh, Mehdi Hedayati, Meghdad Sedaghat, Maryam Sharafkhah and Golbon Sohrab

    Citation: Diabetology & Metabolic Syndrome 2020 12:59

    Content type: Research

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  4. The present study investigated the relationships between psychological stress indices and oxidative stress marker, also when combined with emergent insulin resistance (IR), in the non-diabetic, middle-aged sub...

    Authors: Miroslaw Janczura, Jerzy Dropinski, Anna Gielicz, Katarzyna Kotula-Horowitz, Teresa Iwaniec, Andrzej Stanisz, Rafal Rosa and Teresa B. Domagala

    Citation: Diabetology & Metabolic Syndrome 2020 12:58

    Content type: Research

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  5. Diabetes mellitus (DM) and cardiovascular disease (CVD) are present in a large number of patients with novel Coronavirus disease 2019 (COVID-19). We aimed to determine the risk and predictors of in-hospital mo...

    Authors: Hadith Rastad, Hossein Karim, Hanieh-Sadat Ejtahed, Ramin Tajbakhsh, Mohammad Noorisepehr, Mehrdad Babaei, Mehdi Azimzadeh, Alireza Soleimani, Seyed Hasan Inanloo, Neda Shafiabadi Hassani, Fariba Rasanezhad, Ehsan Shahrestanaki, Zeinab Khodaparast, Hossein Golami and Mostafa Qorbani

    Citation: Diabetology & Metabolic Syndrome 2020 12:57

    Content type: Research

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  6. The American Diabetes Association proposed two subcategories for type 1 diabetes mellitus: type 1A or immune-mediated diabetes (IDM) and type 1B or idiopathic diabetes. The absence of β-cell autoimmune markers...

    Authors: Diana Catarino, Diana Silva, Joana Guiomar, Cristina Ribeiro, Luísa Ruas, Luís Cardoso and Isabel Paiva

    Citation: Diabetology & Metabolic Syndrome 2020 12:56

    Content type: Research

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  7. Diabetic retinopathy (DR) is a specific neurovascular complication of diabetes mellitus (DM). Clinically, family history is a widely recognized risk factor for DR, assisting diagnosis and risk strata. However,...

    Authors: Jin-Rui Wang, Zhongli Chen, Ke Yang, Hui-Jun Yang, Wen-Yu Tao, Yi-Ping Li, Ze-Jia Jiang, Chao-Fang Bai, Yue-Chuan Yin, Jian-Mei Duan, Yuan-Yuan Zhou, Xin-Qian Geng and Ying Yang

    Citation: Diabetology & Metabolic Syndrome 2020 12:55

    Content type: Research

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  8. Sarcopenia is a progressive condition that is characterized by decreases in skeletal muscle mass and function. Although sarcopenia is associated with lifestyle-related diseases (LSRD), the mechanisms underlyin...

    Authors: Takanobu Takata, Akiko Sakasai-Sakai and Masayoshi Takeuchi

    Citation: Diabetology & Metabolic Syndrome 2020 12:54

    Content type: Research

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  9. It is well established that diminished reproductive health is one of the notable long-term outcomes of type 2 diabetes mellitus (T2DM), especially among males. Due to the global increasing rate of T2DM and inf...

    Authors: Marziyeh Rahimiyan-Heravan, Leila Roshangar, Pouran Karimi, Safa Sefidgari-Abrasi, Mohammad Morshedi, Maryam Saghafi-Asl and Khadijeh Bavafa-Valenlia

    Citation: Diabetology & Metabolic Syndrome 2020 12:53

    Content type: Research

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  10. Diabetes mellitus is a chronic disease characterized by high social, economic and health burden, mostly due to the high incidence and morbidity of diabetes complications. Numerous studies have shown that optim...

    Authors: F. Andreozzi, R. Candido, S. Corrao, R. Fornengo, A. Giancaterini, P. Ponzani, M. C. Ponziani, F. Tuccinardi and D. Mannino

    Citation: Diabetology & Metabolic Syndrome 2020 12:52

    Content type: Review

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  11. Previous literatures have implied that the liver fat deposition plays a crucial role in the development and progression of insulin resistance. In the present study, we aimed to investigate the association of l...

    Authors: Yun-Sheng Wang, Jun Ye, Yong-Hong Cao, Rong Zhang, Xiao-Fang Han, Ling-Ling Zou, Lei Kuang, Ji Zhang, Hu Lian, Jin-Xiang Xia, Qiu Zhang and Wu Dai

    Citation: Diabetology & Metabolic Syndrome 2020 12:51

    Content type: Research

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  12. While sufficient evidence supporting universal screening is not available, it is justifiable to look for specific risk factors for gestational diabetes mellitus (GDM) or hyperglycemia in pregnancy (HIP). The o...

    Authors: Bianca F. Nicolosi, Joice M. Vernini, Roberto A. Costa, Claudia G. Magalhães, Marilza V. C. Rudge, José E. Corrente, Jose G. Cecatti and Iracema M. P. Calderon

    Citation: Diabetology & Metabolic Syndrome 2020 12:49

    Content type: Research

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  13. We reported a relatively high rate of MetS in rural Northeast residents in 2012–2013. Many strategies like health knowledge propagation and lifestyle modification have been taken to help rural residents decrea...

    Authors: Shasha Yu, Xiaofan Guo, GuangXiao Li, Hongmei Yang, Guozhe Sun, Liqiang Zheng and Yingxian Sun

    Citation: Diabetology & Metabolic Syndrome 2020 12:48

    Content type: Research

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  14. Type 2 diabetes (T2D) shows a high mortality rate, dependent on disease duration, comorbidities and glucose control over time. Data on patients with short disease duration are scanty.

    Authors: Edoardo Biancalana, Federico Parolini, Alessandro Mengozzi and Anna Solini

    Citation: Diabetology & Metabolic Syndrome 2020 12:47

    Content type: Research

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  15. Reduced sleep quality is common in advanced age. Poor sleep quality is associated with adverse outcomes, chiefly cardiovascular, in young and middle-aged subjects, possibly because of its association with meta...

    Authors: Alice Laudisio, Silvia Giovannini, Panaiotis Finamore, Luca Navarini, Domenico Paolo Emanuele Margiotta, Federica Vannetti, Claudio Macchi, Daniele Coraci, Isabella Imbimbo, Raffaello Molino-Lova, Claudia Loreti, Raffaele Antonelli Incalzi, Giuseppe Zuccalà and Luca Padua

    Citation: Diabetology & Metabolic Syndrome 2020 12:46

    Content type: Research

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  16. In current management of type 2 diabetes (T2DM), cardiovascular and renal prevention have become important targets to be achieved. In this context, a joint panel of four endocrinology societies from Brazil and...

    Authors: Marcello Casaccia Bertoluci, João Eduardo Nunes Salles, José Silva-Nunes, Hermelinda Cordeiro Pedrosa, Rodrigo Oliveira Moreira, Rui Manuel Calado da Silva Duarte, Davide Mauricio da Costa Carvalho, Fábio Rogério Trujilho, João Filipe Cancela dos Santos Raposo, Erika Bezerra Parente, Fernando Valente, Fábio Ferreira de Moura, Alexandre Hohl, Miguel Melo, Francisco Garcia Pestana Araujo, Rosa Maria Monteiro Castro de Araújo Principe…

    Citation: Diabetology & Metabolic Syndrome 2020 12:45

    Content type: Review

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  17. The role of serum fibroblast growth factor 19 (FGF19) in arteriosclerosis is not well known. In the present study, we aimed to explore whether serum FGF19 levels were related to arteriosclerosis parameters, in...

    Authors: Wang-shu Liu, Meng-jie Tang, Tian-li Xu, Jian-bin Su, Xue-qin Wang, Feng Xu, Dong-mei Zhang, Qing Zhu, Jie Cao and Hong Wang

    Citation: Diabetology & Metabolic Syndrome 2020 12:44

    Content type: Research

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  18. Glycosylphosphatidylinositol-specific phospholipase D (GPLD1) is responsible for cleaving membrane-associated glycosylphosphatidylinositol (GPI) molecules, which is affected by diabetes. We aimed to examine th...

    Authors: Farzad Abdolmaleki and Ali Heidarianpour

    Citation: Diabetology & Metabolic Syndrome 2020 12:43

    Content type: Research

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  19. Neuregulin 4 (Nrg4) is a novel neurotrophic adipokine associated with the development of diabetic peripheral neuropathy (DPN), however, the pathological mechanism remains poorly understood. The purpose of our ...

    Authors: Pijun Yan, Zhihong Zhang, Ying Miao, Yong Xu, Jianhua Zhu and Qin Wan

    Citation: Diabetology & Metabolic Syndrome 2020 12:42

    Content type: Research

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  20. Prediabetes can predispose the individual to type 2 diabetes in the long-term. The present study was conducted to determine the effectiveness of vitamin D and omega-3 co-supplementation on glycemic control and...

    Authors: Masoumeh Rajabi-Naeeni, Mahrokh Dolatian, Mostafa Qorbani and Amir Abbas Vaezi

    Citation: Diabetology & Metabolic Syndrome 2020 12:41

    Content type: Research

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  21. Diabetes mellitus in elderly represents an exceptional subset in the population vulnerable to cardiovascular events. As aging, diabetes mellitus and hypertension share common pathways, an ideal treatment shoul...

    Authors: Shaimaa M. Motawea, Rasha I. Noreldin and Yahya M. Naguib

    Citation: Diabetology & Metabolic Syndrome 2020 12:40

    Content type: Research

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  22. LncRNA HAND2-AS1 has been reported to be a tumor suppressor in several types of malignancy, while its involvement in other human diseases is unclear. Our preliminary RNA-seq analysis revealed the downregulatio...

    Authors: Changqing Dong, Shengmao Liu, Yanling Li and Yingchun Cui

    Citation: Diabetology & Metabolic Syndrome 2020 12:39

    Content type: Research

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  23. Emerging observational studies suggest an association between metabolic syndrome (MetS) and osteoarthritis (OA). This meta-analysis was conducted to examine whether or not there is a bidirectional relationship...

    Authors: Sheng-Yao Liu, Wen-Ting Zhu, Bin-Wei Chen, Yuan-Hong Chen and Guo-Xin Ni

    Citation: Diabetology & Metabolic Syndrome 2020 12:38

    Content type: Review

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  24. Sodium–glucose cotransporter 2 (SGLT2) inhibitors are an antihyperglycemic drug with diuretic action. We recently reported that the SGLT2 inhibitor dapagliflozin ameliorates extracellular volume expansion with...

    Authors: Ken Ohara, Takahiro Masuda, Masato Morinari, Mari Okada, Atsushi Miki, Saki Nakagawa, Takuya Murakami, Kentaro Oka, Maki Asakura, Yasuharu Miyazawa, Akito Maeshima, Tetsu Akimoto, Osamu Saito and Daisuke Nagata

    Citation: Diabetology & Metabolic Syndrome 2020 12:37

    Content type: Research

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  25. Recent studies point toward the possible regulatory roles of two lncRNAs; metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) and taurine upregulated gene 1 (TUG1) in the pathogenesis of obesity-re...

    Authors: Reyhane Ebrahimi, Karamollah Toolabi, Naghmeh Jannat Ali Pour, Samaneh Mohassel Azadi, Alireza Bahiraee, Fahimeh Zamani-Garmsiri and Solaleh Emamgholipour

    Citation: Diabetology & Metabolic Syndrome 2020 12:36

    Content type: Research

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  26. The safety of hypoglycemic drugs should be paid more attention to in elderly patients with type 2 diabetes mellitus due to their concomitant diseases, physiological decline of liver and kidney function and cog...

    Authors: Dong-Ni Yu, Lei Qiu, Shang-Yong Ning and Li-Xin Guo

    Citation: Diabetology & Metabolic Syndrome 2020 12:35

    Content type: Research

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  27. Allograft kidney transplantation has become a treatment of choice for patients with end-stage renal disease (ESRD), and post-transplant diabetes mellitus (PTDM) has been associated with impaired patient and gr...

    Authors: Hsuan Yeh, Chihung Lin, Yan-Rong Li, Chieh-Li Yen, Cheng-Chia Lee, Jung-Sheng Chen, Kuan-Hsing Chen, Ya-Chun Tian, Pi-Hua Liu and Ching-Chung Hsiao

    Citation: Diabetology & Metabolic Syndrome 2020 12:34

    Content type: Research

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  28. Diabetic nephropathy (DN) is a severe complication of diabetes with type 1 and 2. Long non-coding RNAs (lncRNAs) are being found to be involved in the DN pathogenesis. In this study, we aimed to further explor...

    Authors: Wen Zhong, Jiaoe Zeng, Junli Xue, Aimin Du and Yancheng Xu

    Citation: Diabetology & Metabolic Syndrome 2020 12:33

    Content type: Research

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  29. It is generally accepted that obesity can lead to metabolic disorders such as NAFLD and insulin resistance. However, the underlying mechanism has been poorly understood. Moreover, there is evidence to support ...

    Authors: Reza Afrisham, Sahar Sadegh-Nejadi, Reza Meshkani, Solaleh Emamgholipour and Maliheh Paknejad

    Citation: Diabetology & Metabolic Syndrome 2020 12:32

    Content type: Research

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  30. Evidence suggests that pathophysiological conditions such as obesity and type 2 diabetes (T2D) are associated with morphologic and metabolic alterations in the small intestinal mucosa. Exploring these alterati...

    Authors: Catherine Lalande, Jean-Philippe Drouin-Chartier, André J. Tremblay, Patrick Couture and Alain Veilleux

    Citation: Diabetology & Metabolic Syndrome 2020 12:31

    Content type: Research

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  31. Diabetes and diabetic complications are considered as leading causes of both morbidity and mortality in the world. Unfortunately, routine medical treatments used for affected patients possess undesirable side ...

    Authors: Mohammad Hossein Pourhanifeh, Azam Hosseinzadeh, Ehsan Dehdashtian, Karim Hemati and Saeed Mehrzadi

    Citation: Diabetology & Metabolic Syndrome 2020 12:30

    Content type: Review

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  32. Obesity and Overweight at an early age can contribute with many chronic diseases such as cancers, diabetes and cardiovascular diseases. Diet-related inflammation is one of the most important underlying mechani...

    Authors: Farhad Vahid, Fatemeh Bourbour, Maryam Gholamalizadeh, Nitin Shivappa, James R. Hébert, Khatereh Babakhani, Alireza Mosavi Jarrahi, Samaneh Mirzaei Dahka and Saeid Doaei

    Citation: Diabetology & Metabolic Syndrome 2020 12:29

    Content type: Research

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  33. Congenital generalized lipodystrophy (CGL) is a rare autosomal recessive disorder characterized by the near-total loss of subcutaneous adipose tissue soon after birth, resulting in ectopic fat deposition and s...

    Authors: Renan Magalhães Montenegro Junior, Grayce Ellen da Cruz Paiva Lima, Virgínia Oliveira Fernandes, Ana Paula Dias Rangel Montenegro, Clarisse Mourão Melo Ponte, Lívia Vasconcelos Martins, Daniel Pascoalino Pinheiro, Maria Elisabete Amaral de Moraes, Manoel Odorico de Moraes Filho and Catarina Brasil d’Alva

    Citation: Diabetology & Metabolic Syndrome 2020 12:28

    Content type: Research

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  34. This study aimed to assess the agreement and efficacy of the Ipswich Touch Test compared to the monofilament test in individuals with type 2 diabetes.

    Authors: Luz Marina Alfonso Dutra, Mirian Conceição Moura, Flaviene Alves do Prado, Giselle De Oliveira Lima, Manuela Costa Melo, Rubens Nelson Morato Fernandez and Maria Rita Carvalho Garbi Novaes

    Citation: Diabetology & Metabolic Syndrome 2020 12:27

    Content type: Research

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  35. Detecting early type 2 diabetes (T2D) risk factors may reduce or prevent the development of the disease. We conducted a pilot study to generate preliminary data on the perception of T2D and further determined ...

    Authors: Janet Antwi, Rebecca Lavin, Stacey Sullivan and Maria Bellavia

    Citation: Diabetology & Metabolic Syndrome 2020 12:25

    Content type: Research

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  36. Type 1 diabetes (T1D) affects psychologically not only the persons with diabetes themselves but affects their family members. Few studies were conducted to investigate mental health in T1D partners. This study...

    Authors: E. Buin, E. J. Pavin and M. S. V. M. Silveira

    Citation: Diabetology & Metabolic Syndrome 2020 12:23

    Content type: Research

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  37. The International Consensus in Time in Range (TIR) was recently released and defined the concept of the time spent in the target range between 70 and 180 mg/dL while reducing time in hypoglycemia, for patients...

    Authors: Monica Andrade Lima Gabbay, Melanie Rodacki, Luis Eduardo Calliari, Andre Gustavo Daher Vianna, Marcio Krakauer, Mauro Scharf Pinto, Janice Sepúlveda Reis, Marcia Puñales, Leonardo Garcia Miranda, Ana Claudia Ramalho, Denise Reis Franco and Hermelinda Pedrosa Cordeiro Pedrosa

    Citation: Diabetology & Metabolic Syndrome 2020 12:22

    Content type: Review

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  38. The use of highly active anti- retroviral therapy (HAART) as well as human immunodeficiency virus (HIV) per se have been shown to be related with diabetes among patients living with HIV. There is limited evide...

    Authors: Alemu Gebrie, Bekele Tesfaye, Tensae Gebru, Fentahun Adane, Worku Abie and Mekonnen Sisay

    Citation: Diabetology & Metabolic Syndrome 2020 12:20

    Content type: Research

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  39. Few studies examined associations between depressive symptoms and metabolic syndrome (MetS) among older Chinese adults. Considering that the prevalence of depressive symptoms is high in older Chinese adults, w...

    Authors: Jing-Hong Liu, Yu-Xi Qian, Qing-Hua Ma, Hong-Peng Sun, Yong Xu and Chen-Wei Pan

    Citation: Diabetology & Metabolic Syndrome 2020 12:18

    Content type: Research

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  40. Existing evidence suggest that low concentrations of vitamin A and E may have a contribution to the development of diabetes complications; however, data regarding the status of vitamin A and E among individual...

    Authors: Hebah Alawi Kutbi and Sahar Ali Hammouda

    Citation: Diabetology & Metabolic Syndrome 2020 12:17

    Content type: Research

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  41. Metabolic syndrome (MS) is a complex disorder represented by a set of cardiovascular risk factors usually related to central fat deposition, insulin resistance, hypertension and dyslipidemia. It is associated ...

    Authors: Ana Denise Brandão, Jeferson Hernandes da Silva, Sarah Mariane Oliveira Lima, Leiciane Lima, Bhianca Loize, Antônio Adolfo Mattos de Castro, Claudia Kümpel and Elias Ferreira Porto

    Citation: Diabetology & Metabolic Syndrome 2020 12:16

    Content type: Research

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  42. To adapt and validate the Clarke and Gold questionnaires and the Edinburgh Hypoglycemia Symptom Scale (EHSS) to Brazilian Portuguese and to determine the prevalence and risk factors associated with impaired aw...

    Authors: Paula Stefenon, André Luís Marques da Silveira, Luana Seminotti Giaretta, Cristiane Bauermann Leitão and Andrea Carla Bauer

    Citation: Diabetology & Metabolic Syndrome 2020 12:15

    Content type: Research

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  43. Obesity is associated with increased general mortality and comorbidities, it is multifactorial and some evidence has shown that sleep duration and shift work may be implicated in its pathogenesis.

    Authors: Maria Carlota Borba Brum, Fábio Fernandes Dantas Filho, Claúdia Carolina Schnorr, Otávio Azevedo Bertoletti, Gustavo Borchardt Bottega and Ticiana da Costa Rodrigues

    Citation: Diabetology & Metabolic Syndrome 2020 12:13

    Content type: Research

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  44. Human data supporting a role for endoplasmic reticulum (ER) stress and calcium dyshomeostasis in diabetes is scarce. Darier disease (DD) is a hereditary skin disease caused by mutations in the ATP2A2 gene encodin...

    Authors: Tara Ahanian, Philip Curman, Ivone U. S. Leong, Kerstin Brismar, Etty Bachar-Wikstrom, Martin Cederlöf and Jakob D. Wikstrom

    Citation: Diabetology & Metabolic Syndrome 2020 12:12

    Content type: Research

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  45. The primary objective of our study was to determine which factors influence health literacy (HL) in patients with type 1 diabetes (T1D) and type 2 diabetes (T2D), and the secondary one was to evaluate the infl...

    Authors: Marilia B. Gomes, Luiza Harcar Muniz, Laura Gomes Nunes Melo, Marcela Haas Pizarro, Bianca Senger Vasconcelos Barros, Deborah Conte Santos and Carlos Antonio Negrato

    Citation: Diabetology & Metabolic Syndrome 2020 12:11

    Content type: Research

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