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  1. The prevalence of diabetes mellitus has risen considerably and currently affects more than 422 million people worldwide. Cardiovascular diseases including myocardial infarction and heart failure represent the ...

    Authors: Melanie S. Hulshoff, Isabel N. Schellinger, Xingbo Xu, Jolien Fledderus, Sandip K. Rath, Fang Cheng Wong, Sabine Maamari, Josephina Haunschild, Guido Krenning, Uwe Raaz and Elisabeth M. Zeisberg
    Citation: Diabetology & Metabolic Syndrome 2023 15:11
    Content type: Research Published on:

  2. Hyperglycemia in pregnancy (HIP) is suggested to be a risk factor for elevated blood pressure (BP) in offspring. However, the empirical evidence was mixed. Thus, this systematic review and meta-analysis was co...

    Authors: Xinyue Zhang, Yinlin Wang, Wenhan Xiao, Denan Jiang, Jiali Zhou, Xinxin Ye, Shiqi Wu, Shuting Li and Peige Song
    Citation: Diabetology & Metabolic Syndrome 2023 15:10
    Content type: Review Published on:

  3. Metabolic syndrome (Mets) is a common metabolic disorder in which hypoadiponectinemia is one of the consequences for the body caused by inflammation, and vitamin D may help improve inflammatory symptoms. LncRN...

    Authors: Mohammad Rashidmayvan, Reza Sahebi, Amir Avan, Payam Sharifan, Habibollah Esmaily, Asma Afshari, Elyas Nattagh-Eshtivani, Fatemeh Najar Sedghdoust, Malihe Aghasizadeh, Gordon A. Ferns and Majid Ghayour-Mobarhan
    Citation: Diabetology & Metabolic Syndrome 2023 15:9
    Content type: Research Published on:

  4. The effectiveness and limb safety of sodium glucose co-transporter 2 inhibitors (SGLT2i) for patients with type-2 diabetes (T2D) who have received peripheral artery disease (PAD) revascularization are unknown.

    Authors: Hsin-Fu Lee, Chi Chuang, Pei-Ru Li, Yung-Hsin Yeh, Yi-Hsin Chan and Lai-Chu See
    Citation: Diabetology & Metabolic Syndrome 2023 15:8
    Content type: Research Published on:

  5. Declined renal function is associated with physical function impairment and frailty in a graded fashion. This study aimed to examine the relationship between renal function, frailty and physical performance wi...

    Authors: Shuo-Chun Weng, Cheng-Fu Lin, Chiann-Yi Hsu and Shih-Yi Lin
    Citation: Diabetology & Metabolic Syndrome 2023 15:7
    Content type: Research Published on:

  6. Experimental and epidemiological studies have indicated an association between diabetes exposure and an increased risk of liver cancer due to nonalcoholic steatohepatitis (NASH). However, to date, no systemati...

    Authors: Ziyi Li, Na Yang, Liyun He, Jialu Wang, Fan Ping, Wei Li, Lingling Xu, Huabing Zhang and Yuxiu Li
    Citation: Diabetology & Metabolic Syndrome 2023 15:6
    Content type: Research Published on:

  7. Gestational diabetes mellitus (GDM) is the most prevalent metabolic disorder during pregnancy, causing short- and long-term complications for both mother and baby. GDM is a multifactorial disease, and it may b...

    Authors: Masoumeh Karami, Seyyed Hossein Mousavi, Mohammad Rafiee, Reza Heidari and Seyedeh Zahra Shahrokhi
    Citation: Diabetology & Metabolic Syndrome 2023 15:5
    Content type: Review Published on:

  8. Control of glucose, blood pressure, cholesterol, and smoking improves the prognosis of individuals with diabetes mellitus. Our objective was to assess the level of control of these risk factors in Brazilian ad...

    Authors: Bruna Cristine Chwal, Rodrigo Citton Padilha dos Reis, Maria Inês Schmidt, Bruce B. Duncan, Sandhi Maria Barreto and Rosane Harter Griep
    Citation: Diabetology & Metabolic Syndrome 2023 15:4
    Content type: Research Published on:

  10. For individuals diagnosed with diabetes mellitus, the practice of properly oriented physical exercises brings significant benefits to the individual's health and is considered an indispensable tool for metabol...

    Authors: William Valadares Campos Pereira, Denise Maria Martins Vancea, Ricardo de Andrade Oliveira, Yuri Galeno Pinheiro Chaves de Freitas, Rodrigo Nunes Lamounier, Wellington S. Silva Júnior, Andrea Messias Britto Fioretti, Clayton Luiz Dornelles Macedo, Marcello Casaccia Bertoluci and Roberto Luis Zagury
    Citation: Diabetology & Metabolic Syndrome 2023 15:2
    Content type: Review Published on:

  11. Intrinsic capacity (IC) is a novel concept focusing on normal and healthy aging. The effect of IC on the risk of chronic kidney disease (CKD) according to KDIGO category in older type 2 diabetes mellitus (T2DM...

    Authors: Wei-Hua Tang, Teng-Hung Yu, Hui-Lan Lee and Yau-Jiunn Lee
    Citation: Diabetology & Metabolic Syndrome 2023 15:1
    Content type: Research Published on:

  12. The hypothesis of the effect of the insulinogenic effects of diet on the development of cardiovascular diseases has been proposed, but the findings of previous studies are very contradictory. We investigated t...

    Authors: Bayyeneh Khoshnoudi-Rad, Somayeh Hosseinpour-Niazi, Maryam Javadi, Parvin Mirmiran and Fereidoun Azizi
    Citation: Diabetology & Metabolic Syndrome 2022 14:198
    Content type: Research Published on:

  13. Diabetes is a major cause of the progression of acute kidney injury (AKI). Few prediction models have been developed to predict the renal prognosis in diabetic patients with AKI so far. The aim of this study w...

    Authors: Manqiu Mo, Zichun Huang, Tianyun Gao, Yuzhen Luo, Xiaojie Pan, Zhenhua Yang, Ning Xia, Yunhua Liao and Ling Pan
    Citation: Diabetology & Metabolic Syndrome 2022 14:197
    Content type: Research Published on:

  14. Diabetes as a metabolic illness can be characterized by increased amounts of blood glucose. This abnormal increase can lead to critical detriment to the other organs such as the kidneys, eyes, heart, nerves, a...

    Authors: Elaheh Afsaneh, Amin Sharifdini, Hadi Ghazzaghi and Mohadeseh Zarei Ghobadi
    Citation: Diabetology & Metabolic Syndrome 2022 14:196
    Content type: Review Published on:

  15. Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have been highly recommended for glycemic control and weight reduction. However, evidence has accumulated that GLP-1 RAs treatment is related to an increas...

    Authors: Sijin Wu, Wenzhao Lu, Zhongli Chen, Yan Dai, Keping Chen and Shu Zhang
    Citation: Diabetology & Metabolic Syndrome 2022 14:195
    Content type: Review Published on:

  16. The incidence of gestational diabetes mellitus (GDM) is increasing worldwide, and has been associated with some changes in the gut microbiota. Studies have shown that the maternal gut microbiota pattern with h...

    Authors: Patricia Medici Dualib, Gabriel Fernandes, Carla R. Taddei, Camila R. S. Carvalho, Luiz Gustavo Sparvoli, Célia Bittencourt, Isis T. Silva, Rosiane Mattar, Sandra R. G. Ferreira, Sergio A. Dib and Bianca de Almeida-Pititto
    Citation: Diabetology & Metabolic Syndrome 2022 14:194
    Content type: Research Published on:

  17. Glucagon (traditional kits for intramuscular administration, Glucagon and Glucagen), although recommended as a remedy for severe hypoglycemia (SH), has been reported to be under-utilized, likely because of tec...

    Authors: Antonio E. Pontiroli, Manfredi Rizzo and Elena Tagliabue
    Citation: Diabetology & Metabolic Syndrome 2022 14:193
    Content type: Brief Report Published on:

  18. Type 2 diabetes mellitus is associated with an increased risk of impaired quality of life. Improving health related quality of life (HRQoL) is therefore an important goal in the multimodal management of diabet...

    Authors: Madeleine Hummel, Stephanie Erika Bonn and Ylva Trolle Lagerros
    Citation: Diabetology & Metabolic Syndrome 2022 14:192
    Content type: Research Published on:

  19. Triglyceride and glucose (TyG) index, triglyceride glucose-body mass (TyG-BMI) index, triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio, and metabolic score for insulin resistance (METS-IR)...

    Authors: Yu Zhang, Ruiling Wang, Xuelian Fu and Haiyan Song
    Citation: Diabetology & Metabolic Syndrome 2022 14:191
    Content type: Research Published on:

  20. Gestational diabetes mellitus (GDM) is the most common complication during pregnancy, occurring under the combined action of environmental and genetic factors. Genetic variants of glucagon-like peptide-1 recep...

    Authors: Ping Luo, Ying Fan, Yusha Xiong, Hua Feng, Zhiping Yang, Chunlin Zhang and Bing Mei
    Citation: Diabetology & Metabolic Syndrome 2022 14:190
    Content type: Research Published on:

  21. Insulin therapy regimens for people with type 1 diabetes (PWT1D) should mimic the physiological insulin secretion that occurs in individuals without diabetes. Intensive insulin therapy, whether by multiple dai...

    Authors: Wellington S. Silva Júnior, Monica Andrade Lima Gabbay, Rodrigo Nunes Lamounier, Luis Eduardo Calliari and Marcello Casaccia Bertoluci
    Citation: Diabetology & Metabolic Syndrome 2022 14:189
    Content type: Review Published on:

  22. Proliferative diabetic retinopathy (PDR) is a major diabetic microvascular complication, characterized by pathological angiogenesis. This study sets out to investigate the potential molecular mechanism in the ...

    Authors: Ping Wang, Chengqian Li, Yujie Deng, Qing Yu, Xuxia Meng, Tao Jiang, Qing Wang and Yudong Fu
    Citation: Diabetology & Metabolic Syndrome 2022 14:188
    Content type: Research Published on:

  23. The purpose of this study was to assess the effectiveness and safety of a model predictive control (MPC) algorithm for an artificial pancreas system in outpatients with type 1 diabetes.

    Authors: Su Lim Kang, Yoo Na Hwang, Ji Yean Kwon and Sung Min Kim
    Citation: Diabetology & Metabolic Syndrome 2022 14:187
    Content type: Review Published on:

  24. Obesity and overweight are major risk factors for several chronic diseases. There is limited systematic evaluation of risk equations that predict the likelihood of developing an obesity or overweight associate...

    Authors: Adam Ben Taieb, Erika Roberts, Maria Luckevich, Sara Larsen, Carel W. le Roux, Paulo Gomes de Freitas and Dingeman Wolfert
    Citation: Diabetology & Metabolic Syndrome 2022 14:186
    Content type: Review Published on:

  25. Hemoglobin glycation index (HGI), which is calculated by blood glucose and hemoglobin A1c(HbA1c), reflects the individual discrepancy in HbA1c. This study aimed to investigate the association between HGI/HbA1c...

    Authors: Ying Wei, Zhenyu Wu, Ying Wang, Guang Wang and Jia Liu
    Citation: Diabetology & Metabolic Syndrome 2022 14:185
    Content type: Research Published on:

  26. Insulin resistance (IR) was reported to be associated with renal function impairment, but little is known about the gender difference. Hence, our study aimed to investigate the relationship between IR (estimat...

    Authors: Chieh-An Lin, Wen-Cheng Li, Szu-Yu Lin, Yi-Chuan Chen, Wei Yu, Hsiung-Ying Huang, Xue-Jie Xiong and Jau-Yuan Chen
    Citation: Diabetology & Metabolic Syndrome 2022 14:184
    Content type: Research Published on:

  27. Diabetic foot ulcers (DFU) are one of the leading long-term complications experienced by patients with diabetes. Dipeptidyl Peptidase 4 inhibitors (DPP4is) are a class of antihyperglycemic medications prescrib...

    Authors: Venkat N. Vangaveti, Shaurya Jhamb, Oliver Hayes, Julie Goodall, Jacqueline Bulbrook, Kelvin Robertson, Erik Biros, Kunwarjit S. Sangla and Usman H. Malabu
    Citation: Diabetology & Metabolic Syndrome 2022 14:183
    Content type: Research Published on:

  28. Research suggests that fibrinogen (Fib) concentrations are used to assess the occurrence and severity of diabetic foot (DF) and to monitor the progression of diabetic foot in patients. However, its correlation...

    Authors: Jinying Zhang, Jiayu Lin, Bo Liang, Lijun Chen, Xinna Yang and Mimi Li
    Citation: Diabetology & Metabolic Syndrome 2022 14:182
    Content type: Research Published on:

  29. As the nonalcoholic fatty liver disease (NAFLD) epidemic matures, understanding how metabolic changes in NAFLD development vary over the age distribution is important to guide precise prevention. We aimed to c...

    Authors: Yansong Lin, Xiongcai Feng, Xu Cao, Rong Miao, Yanhong Sun, Rui Li, Junzhao Ye and Bihui Zhong
    Citation: Diabetology & Metabolic Syndrome 2022 14:181
    Content type: Research Published on:

  30. Patients with diabetes are prone to asymptomatic hypoglycemia (AH) due to diminished ability to perceive the onset of hypoglycemia. However, the actual prevalence and influencing factors of AH in outpatients w...

    Authors: Bingkun Huang, Qiuhui Jiang, Ting Wu, Qingbao Shen, Wengui Wang, Shoubi Wang, Yinxiang Huang, Shunhua Wang, Peiying Huang, Mingzhu Lin, Xiulin Shi and Xuejun Li
    Citation: Diabetology & Metabolic Syndrome 2022 14:180
    Content type: Research Published on:

  32. There is a lack of nationally representative evidence from the U.S. investigating the relationships between depression and diabetes management behaviors. Our study aimed to assess the associations between diab...

    Authors: Tim C. Lai, Cassidi C. McDaniel and Chiahung Chou
    Citation: Diabetology & Metabolic Syndrome 2022 14:178
    Content type: Research Published on:

  33. Women with diabetes first diagnosed during pregnancy (overt diabetes) may be at the same risk level of adverse outcomes as those with known pregestational diabetes. We compared pregnancy outcomes between these...

    Authors: Maria Lúcia Oppermann, Maria Amélia Campos, Vânia Naomi Hirakata and Angela Jacob Reichelt
    Citation: Diabetology & Metabolic Syndrome 2022 14:177
    Content type: Research Published on:

  34. The serum creatinine-to-cystatin C ratio (Scr/Scys) has been suggested as a surrogate marker of muscle mass and a predictor of adverse outcomes in many diseases. However, the prognostic value of Scr/Scys in pa...

    Authors: Wen Wei, Shanggang Li, Jin Liu, Yong Liu, Kaihong Chen, Shiqun Chen, Mei Tu and Hong Chen
    Citation: Diabetology & Metabolic Syndrome 2022 14:176
    Content type: Research Published on:

  35. It is a growing importance to induce a new treatment approach to encourage weight loss but also to improve maintenance of lost weight. It has been shown that promotion of brown adipose tissue (BAT) function or...

    Authors: Marina Nikolic, Jovana Novakovic, Galina Ramenskaya, Vladimir Kokorekin, Nevena Jeremic and Vladimir Jakovljevic
    Citation: Diabetology & Metabolic Syndrome 2022 14:175
    Content type: Review Published on:

  37. Patients with metabolic syndrome (MS) have a higher incidence of cardiovascular disease (CVD), but the possible mechanisms are not fully understood and further exploration of the possible factors influencing t...

    Authors: Zhe Shu, Xiong Ding, Qing Yue, XiaoXu Ma, MinHong Liu, YunTao Wu, Peng Yang, Ying Wu, Yun Li and Shouling Wu
    Citation: Diabetology & Metabolic Syndrome 2022 14:173
    Content type: Research Published on:

  38. Compromised intestinal barrier integrity can be independently driven by hyperglycemia, and both hyperglycemia and intestinal barrier injury are associated with poor prognosis in critical illness. This study in...

    Authors: Yi-Feng Wang, Feng-Ming Liang, Min Liu, Li-Cheng Ding, Jiao-Jie Hui, Hong-Yang Xu and Li-Jun Liu
    Citation: Diabetology & Metabolic Syndrome 2022 14:172
    Content type: Research Published on:

  39. Nowadays, obesity is one of the largest public health problems worldwide. In the last few decades, there has been a marked increase in the obesity epidemic and its related comorbidities. Worldwide, more than 2...

    Authors: Feng-Yao Wu and Rui-Xing Yin
    Citation: Diabetology & Metabolic Syndrome 2022 14:171
    Content type: Review Published on:

  40. Systemic inflammation and oxidative burden in patients with type 2 diabetes mellitus (T2DM) causes deleterious cardiovascular outcomes. We sought to investigate the clinical antioxidative and anti-inflammatory...

    Authors: Sepehr Gohari, Tara Reshadmanesh, Hadi Khodabandehloo, Amir Karbalaee-Hasani, Hassan Ahangar, Shahram Arsang-Jang, Faramarz Ismail-Beigi, Mohsen Dadashi, Samin Ghanbari, Homa Taheri, Mojtaba Fathi, Muhammad Javad Muhammadi, Reyhaneh Mahmoodian, Atieh Asgari, Mohammadreza Tayaranian, Mehdi Moharrami…
    Citation: Diabetology & Metabolic Syndrome 2022 14:170
    Content type: Research Published on:

  41. Although physical activity is widely recommended for preventing and treating cardiovascular complications of type 2 diabetes mellitus (T2DM), the underlying mechanisms remain unknown. MicroRNA-126 (miR-126) is...

    Authors: Yixiao Ma, Hua Liu, Yong Wang, Junjie Xuan, Xing Gao, Huixian Ding, Chunlian Ma, Yanfang Chen and Yi Yang
    Citation: Diabetology & Metabolic Syndrome 2022 14:169
    Content type: Review Published on:

  42. The role of glycemic control, both prior and during hospitalization, on mortality from COVID-19 in diabetic patients is debated. Furthermore, it is not clear whether hyperglycemia has a direct effect or requir...

    Authors: Sara Madaschi, Eugenia Resmini, Silvia Bonfadini, Giulia Massari, Paola Gamba, Marco Sandri, Stefano Calza, Elena Cimino, Emanuela Zarra, Silvia Dotti, Cristina Mascadri, Barbara Agosti, Emirena Garrafa and Angela Girelli
    Citation: Diabetology & Metabolic Syndrome 2022 14:168
    Content type: Research Published on:

  43. It is still debatable whether glycated albumin/glycated hemoglobin A1C (GA/HbA1C) ratio is associated with metabolic dysfunction-associated fatty liver disease (MAFLD), and few studies have been conducted in t...

    Authors: Jun-Wei Wang, Chun-Hua Jin, Jiang-Feng Ke, Yi-Lin Ma, Yu-Jie Wang, Jun-Xi Lu, Mei-Fang Li and Lian-Xi Li
    Citation: Diabetology & Metabolic Syndrome 2022 14:167
    Content type: Research Published on:

  44. Evidence showed possible benefits of a less gestational weight gain (GWG) than the US Institute of Medicine (IOM) recommendation in gestational diabetes mellitus (GDM) pregnancy. Here, we aimed to explore an a...

    Authors: Xiaoqin Luo, Jiayi Gao, Zhangya He, Jing Ji, Wanyu Zhang, Pei Wu, Xiaoxiao Guo, Dan Cao, Zhangrui Xu, Chao Li and Yang Mi
    Citation: Diabetology & Metabolic Syndrome 2022 14:166
    Content type: Research Published on:

  45. Rheumatoid arthritis, metabolic syndrome (MS) and cardiovascular disease (CVD) are mutually connected. We aim to investigate the association between rheumatoid factor (RF) and MS in general population, explore...

    Authors: Lan Li, Donglai Feng, Jing Zeng, Peng Ye, Yao Chen and Dong Wei
    Citation: Diabetology & Metabolic Syndrome 2022 14:165
    Content type: Research Published on:

  46. During pandemic period, a single fast glycemia value (≥ 92 mg/dl) performed within the recommended time window for the risk level defined by the Italian guidelines, was considered an acceptable surrogate for G...

    Authors: Rosario D’Anna, Antonio Di Benedetto, Stefania Palella, Alessia Miceli, Paola Romeo and Francesco Corrado
    Citation: Diabetology & Metabolic Syndrome 2022 14:164
    Content type: Research Published on:

  47. Diabetic hepatopathy is a serious complication of poorly controlled diabetes mellitus. An efficient antidiabetic drug which keeps normal liver tissues is not available. The renin-angiotensin system has been re...

    Authors: Amal M. Mahfoz and Aya Y. Gawish
    Citation: Diabetology & Metabolic Syndrome 2022 14:163
    Content type: Research Published on:

  48. The hemoglobin glycation index (HGI) is the difference between measured and estimated glycation of hemoglobin. However, there is limited evidence to investigate the HGI and the clinical outcomes of acute coron...

    Authors: Jiayu Li, Yanguo Xin, Jingye Li, Li Zhou, Hui Qiu, Aidong Shen, Hui Chen and Hongwei Li
    Citation: Diabetology & Metabolic Syndrome 2022 14:162
    Content type: Research Published on:

  49. Insulin resistance (IR) is an important contributor to the development of hypertension (HTN), and the triglyceride-glucose (TyG) index has been proposed as a simple, reliable marker of IR. This study investiga...

    Authors: Dong-Hwa Lee, Jong Eun Park, So Young Kim, Hyun Jeong Jeon and Jong-Hyock Park
    Citation: Diabetology & Metabolic Syndrome 2022 14:161
    Content type: Research Published on:

  50. Asian Indians (AI) are at high risk for both atherosclerotic diseases (ATH) and diabetes mellitus (DM). We analyze the clustering of these two comorbidities as contributing causes of death in AI versus Non-AI ...

    Authors: Deepak R. Nair, Abhyuday Chauhan and Dhananjay Vaidya
    Citation: Diabetology & Metabolic Syndrome 2022 14:159
    Content type: Research Published on:

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