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Table 3 Association of serum TB quintiles with lower limb atherosclerosis

From: High-normal serum bilirubin decreased the risk of lower limb atherosclerosis in type 2 diabetes: a real-world study

 

ORs (95%CI)

p value

 

Q1

Q2

Q3

Q4

Q5

for trend

Lower limb plaque

Model 1

1(ref)

0.884(0.745–1.049)

0.700(0.588–0.834)

0.735(0.620–0.871)

0.614(0.523–0.720)

< 0.001

Model 2

1(ref)

0.890(0.723–1.095)

0.667(0.540–0.825)

0.732(0.595–0.901)

0.683(0.560–0.833)

< 0.001

Model 3

1(ref)

0.894(0.726–1.101)

0.668(0.540–0.826)

0.736(0.598–0.905)

0.686(0.563–0.837)

< 0.001

Model 4

1(ref)

0.934(0.755–1.156)

0.680(0.547–0.845)

0.762(0.616–0.942)

0.726(0.592–0.890)

0.001

Model 5

1(ref)

0.955(0.755–1.207)

0.634(0.501–0.803)

0.762(0.602–0.965)

0.797(0.633–1.003)

0.001

Model 6

1(ref)

0.964(0.746–1.246)

0.677(0.522–0.877)

0.770(0.597–0.992)

0.774(0.601–0.997)

0.015

Lower limb stenosis

Model 1

1(ref)

0.778(0.647–0.937)

0.572(0.464–0.704)

0.558(0.457–0.682)

0.511(0.422–0.620)

< 0.001

Model 2

1(ref)

0.775(0.627–0.959)

0.582(0.460–0.737)

0.582(0.463–0.730)

0.600(0.480–0.749)

< 0.001

Model 3

1(ref)

0.780(0.628–0.968)

0.600(0.472–0.762)

0.619(0.491–0.779)

0.627(0.501–0.785)

< 0.001

Model 4

1(ref)

0.790(0.635–0.982)

0.605(0.475–0.770)

0.631(0.500-0.796)

0.652(0.520–0.819)

< 0.001

Model 5

1(ref)

0.783(0.612–1.002)

0.667(0.512–0.869)

0.648(0.498–0.842)

0.718(0.554–0.931)

0.006

Model 6

1(ref)

0.697(0.529–0.918)

0.664(0.496–0.889)

0.661(0.494–0.884)

0.706(0.524–0.953)

0.016

  1. Model 1: unadjusted
  2. Model 2: age, sex, and DD
  3. Model 3: Model 2 + smoking status, alcohol intake, hypertension, and obesity
  4. Model 4: Model 3 + use of APAs, AHAs, LLDs and IIAs
  5. Model 5: Model 4 + SBP, DBP, WC, WHR and BMI
  6. Model 6: Model 5 + ALT, AST, γ-GT, TTG, TC, HDL-C, LDL-C, Lp(a), eGFR, SUA, UAE, FPG, 2 h PPG, HbA1C, FCP, 2 h PCP, Fins, 2hins, and CRP