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Table 3 Association of MetS (2020 Edition), its components, number and metabolic scores with incident MCI using logistic regression analysis among hemodialysis patients

From: Associations of metabolic syndrome, its severity with cognitive impairment among hemodialysis patients

Characteristics

Model 1

Model 2

Model 3

Mutual model

OR(95%CI)

P

OR(95%CI)

P

OR(95%CI)

P

OR(95%CI)

P

MetS (2020 Edition)

1.31 (1.17, 1.47)

 < 0.001

1.21 (1.08, 1.36)

0.001

1.22 (1.08, 1.37)

0.001

–

 

MetS component

 Abdominal obesity (%)

1.35 (1.20, 1.51)

 < 0.001

1.14 (1.01, 1.29)

0.032

1.14 (1.01, 1.28)

0.039

1.15 (1.01, 1.30)

0.031

 Hypertriglyceridemia (%)

1.12 (0.99, 1.25)

0.054

1.10 (0.98, 1.23)

0.105

1.11 (0.99, 1.24)

0.089

1.09 (0.97, 1.23)

0.145

 Low HDL-c (%)

1.06 (0.95, 1.19)

0.311

1.11 (0.99, 1.24)

0.088

1.11 (0.99, 1.25)

0.079

1.04 (0.85, 1.27)

0.695

 Hyperglycemia (%)

1.30 (1.16, 1.47)

 < 0.001

1.18 (1.04, 1.33)

0.010

1.17 (1.04, 1.33)

0.011

1.28 (0.98, 1.68)

0.070

 High blood pressure (%)

1.24 (0.97, 1.59)

0.087

1.24 (0.96, 1.59)

0.099

1.24 (0.96, 1.60)

0.093

1.09 (0.97, 1.22)

0.168

Number of MetS components

      

–

 

 0

References

 

References

 

References

   

 1

1.73 (0.88, 3.40)

0.115

1.79 (0.90, 3.55)

0.098

1.86 (0.93, 3.71)

0.078

  

 2

1.99 (1.03, 3.87)

0.041

1.93 (0.99, 3.76)

0.055

2.03 (1.04, 3.98)

0.039

  

 3

2.56 (1.32, 4.95)

0.005

2.36 (1.21, 4.60)

0.012

2.51 (1.28, 4.90)

0.007

  

 4

2.60 (1.34, 5.05)

0.005

2.24 (1.15, 4.38)

0.018

2.35 (1.20, 4.62)

0.013

  

 5

3.52 (1.79, 6.91)

 < 0.001

2.78 (1.40, 5.51)

0.003

2.94 (1.48, 5.84)

0.002

  

 siMS score

1.09 (1.05, 1.14)

 < 0.001

1.06 (1.02, 1.11)

0.007

1.06 (1.02, 1.11)

0.008

  

 CMI

1.10 (1.04, 1.16)

0.001

1.08 (1.02, 1.14)

0.006

1.08 (1.02, 1.14)

0.009

  

 MetSSS

1.12 (1.08, 1.16)

 < 0.001

1.06 (1.02, 1.11)

0.007

1.06 (1.02, 1.11)

0.006

  
  1. Model 1, crude model; Model 2, adjusted for age, gender; Model 3, adjusted for age, gender, educational level, smoking history, alcohol history, living alone, dialysis vintage, dialysis modality, dialysis access, and hemoglobin levels. Mutual Model, adjusted for other MetS components as continuous variables based on Model 3, respectively. MetS Metabolic syndrome, MCI Mild cognitive impairment, OR Odds ratio, CI Confidence interval, HDL High density lipoprotein, siMS Metabolic syndrome score, CMI Cardiometabolic index, MetSSS Metabolic syndrome severity score