Skip to main content

Table 2 Association of MetS (2020 Edition) and metabolic scores with MMSE score, and specific cognitive domains using linear regression analysis among hemodialysis patients

From: Associations of metabolic syndrome, its severity with cognitive impairment among hemodialysis patients

Characteristics

Model 1

Model 2

Model 3

 

β (95%CI)

P

β (95%CI)

P

β (95%CI)

P

MetS (2020 Edition)

 MMSE score

− 0.496 (− 0.700, − 0.292)

 < 0.001

− 0.317 (− 0.517, − 0.117)

0.002

− 0.324 (− 0.523, − 0.125)

 < 0.001

 Orientation

− 0.108 (− 0.172, − 0.044)

0.001

− 0.074 (− 0.138, − 0.011)

0.022

− 0.075 (− 0.139, − 0.012)

0.020

 Registration

− 0.039 (− 0.063, − 0.014)

0.002

− 0.026 (− 0.051, − 0.001)

0.040

− 0.026 (− 0.051, − 0.002)

0.036

 Attention and calculation

− 0.068 (− 0.150,0.014)

0.102

− 0.015 (− 0.096, 0.066)

0.712

− 0.025 (− 0.105, 0.056)

0.550

 Recall

0.091 (− 0.139, − 0.042)

 < 0.001

− 0.056 (− 0.104, − 0.007)

0.024

− 0.056 (− 0.104, − 0.008)

0.021

 Language

− 0.188 (− 0.257, − 0.119)

 < 0.001

− 0.143 (− 0.211, − 0.074)

 < 0.001

− 0.141 (− 0.209, − 0.072)

 < 0.001

siMS score

 MMSE score

− 0.192 (− 0.270, − 0.113)

 < 0.001

− 0.126 (− 0.203, − 0.049)

0.001

− 0.123 (− 0.199,− 0.046)

0.002

 Orientation

− 0.055 (− 0.080, − 0.030)

 < 0.001

− 0.042 (− 0.066, − 0.017)

0.001

− 0.041 (− 0.065,− 0.016)

0.001

 Registration

− 0.013 (− 0.023, − 0.004)

0.007

− 0.009 (− 0.018, 0.001)

0.073

− 0.009 (− 0.018, 0.001)

0.078

 Attention and calculation

− 0.036 (− 0.068, − 0.005)

0.025

− 0.011 (− 0.042, 0.020)

0.476

− 0.012 (− 0.043, 0.019)

0.434

 Recall

− 0.021 (− 0.040, − 0.003)

0.025

− 0.012 (− 0.031, 0.006)

0.194

− 0.011 (− 0.030, 0.007)

0.227

 Language

− 0.059 (− 0.086, − 0.033)

 < 0.001

− 0.046 (− 0.072, − 0.019)

0.001

− 0.044 (− 0.071, − 0.018)

0.001

CMI

 MMSE score

− 0.213 (− 0.312, − 0.114)

 < 0.001

− 0.166 (− 0.263, − 0.070)

0.001

− 0.160 (− 0.256, − 0.065)

0.001

 Orientation

− 0.076 (− 0.107, − 0.045)

 < 0.001

− 0.066 (− 0.097, − 0.036)

 < 0.001

− 0.066 (− 0.096, − 0.036)

 < 0.001

 Registration

− 0.012 (− 0.024, 0.000)

0.050

− 0.009 (− 0.073, − 0.023)

 < 0.001

− 0.008 (− 0.020, 0.004)

0.168

 Attention and calculation

− 0.024 (− 0.064, 0.015)

0.229

− 0.008 (− 0.047, 0.031)

0.685

− 0.006 (− 0.045, 0.032)

0.750

 Recall

− 0.016 (− 0.039, 0.008)

0.184

− 0.009 (− 0.032, 0.015)

0.469

− 0.007 (− 0.030, 0.017)

0.579

 Language

− 0.080 (− 0.114, − 0.047)

 < 0.001

− 0.070 (− 0.103, − 0.037)

 < 0.001

− 0.069 (− 0.102, − 0.036)

 < 0.001

MetSSS

 MMSE score

− 0.231 (− 0.303, − 0.159)

 < 0.001

− 0.106 (− 0.180,-0.033)

0.005

− 0.107 (− 0.180, − 0.034)

0.004

 Orientation

− 0.054 (− 0.076, − 0.031)

 < 0.001

− 0.027 (− 0.050, − 0.004)

0.022

− 0.027 (− 0.050, − 0.004)

0.023

 Registration

− 0.018 (− 0.026, − 0.009)

 < 0.001

− 0.009 (− 0.018, 0.000)

0.043

− 0.009 (− 0.019, − 0.000)

0.042

 Attention and calculation

− 0.064 (− 0.093, − 0.035)

 < 0.001

− 0.011 (− 0.040, 0.019)

0.474

− 0.014 (− 0.043, 0.016)

0.355

 Recall

− 0.028 (− 0.045, − 0.011)

0.001

− 0.016 (− 0.033, 0.001)

0.067

− 0.013 (− 0.031, 0.004)

0.132

 Language

− 0.064 (− 0.087, − 0.039)

 < 0.001

− 0.040 (− 0.065, − 0.015)

0.002

− 0.039 (− 0.064, − 0.014)

0.002

  1. Model 1, crude model; Model 2, adjusted for age, sex; Model 3, adjusted for age, sex, educational level, smoking history, alcohol history, living alone, dialysis vintage, dialysis modality, dialysis access, and hemoglobin levels. MetS Metabolic syndrome, MMSE Mini-mental state examination, β Unstandardized coefficient, CI Confidence interval, siMS Metabolic syndrome score, CMI Cardiometabolic index, MetSSS Metabolic syndrome severity score