Table 1 Baseline characteristics of hemodialysis patients according to cognitive function
Characteristics | All (n = 5492) | Normal cognition (n = 3609) | MCI (n = 1883) | P |
|---|---|---|---|---|
MMSE score | 26.9 ± 3.8 | 29.2 ± 1.1 | 22.7 ± 2.6 |  < 0.001 |
Age (year) | 54.4 ± 15.2 | 52.4 ± 15.0 | 58.2 ± 14.9 |  < 0.001 |
Female sex (n, %) | 2141(39.0%) | 1309(26.3%) | 832(44.2%) |  < 0.001 |
Smoking history (n, %) | 1533 (27.9%) | 1021 (28.3%) | 512 (27.2%) | 0.392 |
Alcohol history (n, %) | 485 (8.8%) | 291 (8.1%) | 194 (10.3%) | 0.006 |
High educational level (n, %) | 2205 (40.1%) | 1527 (42.3%) | 678 (36.0%) |  < 0.001 |
Living alone (n, %) | 4152 (75.6%) | 2876 (79.7%) | 1276 (67.8%) |  < 0.001 |
Diabetes mellitus (n, %) | 1512 (27.5%) | 906 (25.1%) | 606 (32.3%) |  < 0.001 |
Hypertension (n, %) | 4336 (79.0%) | 2777 (76.9%) | 1559 (82.8%) |  < 0.001 |
Dialysis vintage (months) | 37.0 (15.0, 70.0) | 37.0 (15.0, 72.0) | 37.0 (15.0, 67.0) | 0.356 |
Dialysis modality (n, %) | Â | Â | Â | 0.334 |
HD | 490 (8.9%) | 312 (8.6%) | 178 (9.5%) | Â |
HD + HDF | 678 (12.3%) | 462 (12.8%) | 216 (11.5%) |  |
HD + HP | 391 (7.1%) | 249 (6.9%) | 142 (7.5%) |  |
HD + HDF + HP | 3933 (71.6%) | 2586 (71.7%) | 1347 (71.5%) |  |
Dialysis access, Fistula (n, %) | 4733 (86.2%) | 3139 (87.0%) | 1594 (84.7%) | 0.108 |
SBP (mmHg) | 138.1 ± 20.6 | 138.1 ± 20.2 | 138.2 ± 21.2 | 0.844 |
DBP (mmHg) | 78.6 ± 13.6 | 97.6 ± 13.6 | 76.7 ± 13.5 |  < 0.001 |
Body height (cm) | 161.0 ± 8.2 | 161.8 ± 8.1 | 159.5 ± 8.3 |  < 0.001 |
Body weight (kg) | 47.4 ± 19.8 | 49.9 ± 19.2 | 42.8 ± 20.0 |  < 0.001 |
Waist circumference (cm) | 83.3 ± 10.8 | 82.8 ± 10.7 | 84.3 ± 10.8 |  < 0.001 |
Hip circumference (cm) | 89.5 ± 8.1 | 89.3 ± 8.1 | 89.8 ± 8.1 | 0.025 |
Fasting glucose (mmol/L) | 7.5 ± 3.8 | 7.4 ± 3.7 | 7.7 ± 4.0 | 0.012 |
Hemoglobin (g/L) | 108.4 ± 20.6 | 109.0 ± 20.4 | 107.5 ± 21.0 | 0.011 |
TG (mmol/L) | 1.51 (1.06, 2.31) | 1.49 (1.05, 2.29) | 1.55 (1.07, 2.36) | 0.060 |
Cholesterol (mmol/L) | 3.90 ± 0.96 | 3.88 ± 0.97 | 3.93 ± 0.96 | 0.059 |
HDL-c (mmol/L) | 1.11 (0.91, 1.35) | 1.11 (0.91, 1.35) | 1.09 (0.90, 1.35) | 0.556 |
LDL-c (mmol/L) | 2.08 (1.63, 2.60) | 2.07 (1.63, 2.59) | 2.10 (1.63, 2.63) | 0.236 |
MetS (2020 Edition) (%) | 3161 (57.6%) | 1996 (55.3%) | 1165 (61.9%) |  < 0.001 |
MetS component | 2.8 ± 1.1 | 2.7 ± 1.1 | 2.9 ± 1.1 |  < 0.001 |
Abdominal obesity (n, %) | 1818 (33.1%) | 1112 (30.8%) | 706 (37.5%) |  < 0.001 |
Hypertriglyceridemia (n, %) | 2384 (43.4%) | 1533 (42.5%) | 851 (45.2%) | 0.055 |
Low HDL-c (n, %) | 2346 (42.7%) | 1524 (42.2%) | 822 (43.7%) | 0.315 |
Hyperglycemia (n, %) | 3550 (64.6%) | 2259 (62.6%) | 1291 (68.6%) |  < 0.001 |
High blood pressure (n, %) | 5117 (94.3%) | 3388 (93.9%) | 1789 (95.0%) | 0.087 |
siMS score | 3.52 ± 1.28 | 3.47 ± 1.24 | 2.62 ± 1.37 |  < 0.001 |
CMI | 0.70 (0.44, 1.21) | 0.68 (0.43, 1.18) | 0.75 (0.44, 1.26) | 0.004 |
MetSSS | 0.83 (0.08, 1.70) | 0.75 (0.05, 1.62) | 0.98 (0.19, 1.88) |  < 0.001 |