Table 3 Summary of the GRADE quality of evidence assessment
Quality Assessment | Number of Patients | SMD (95% CI) | Quality | ||||||
|---|---|---|---|---|---|---|---|---|---|
# Studies | Risk of Bias | Inconsistency | Indirectness | Imprecision | Publication Bias | DM | Control | ||
DM vs. Healthy Controls | |||||||||
13 | Not serious | Serious | Not serious | Not serious | Not serious | 888 | 751 | 1.00 [0.81, 1.19] | ⊕⊕⊕Ο Moderate†|
DM without other comorbidities vs. Healthy Controls | |||||||||
9 | Not serious | Serious | Not serious | Not serious | Not serious | 705 | 458 | 1.03 [0.79, 1.28] | ⊕⊕⊕Ο Moderate†|
T2DM vs. Healthy Controls | |||||||||
10 | Not serious | Serious | Not serious | Not serious | Not serious | 641 | 394 | 1.01 [0.20, 1.67] | ⊕⊕⊕Ο Moderate†|
T2DM without other comorbidities vs. Healthy Controls | |||||||||
8 | Not serious | Serious | Not serious | Not serious | Not serious | 805 | 590 | 1.02 [0.74, 1.31] | ⊕⊕⊕Ο Moderate†|